Obesity: Cannabis Research
Overview
Obesity is a medical condition in which excess body fat has accumulated to the extent that it may have a negative effect on health, leading to reduced life expectancy and/or increased health problems.

Science & Research
Undated - News ~ Hemp & GLA: Good Fat Burns Bad Fat
2014 - Study ~ CB1 blockade-induced weight loss over 48 weeks decreases liver fat in proportion to weight loss in humans
2014 - Study ~ Effect of intermittent cold exposure on brown fat activation, obesity, and energy
homeostasis in mice.
2013 - Study ~ Reduced endothelium-dependent relaxation to anandamide in mesenteric arteries from young obese zucker rats.
2013 - Study ~ Alterations to Melanocortinergic, GABAergic and Cannabinoid Neurotransmission Associated with Olanzapine-Induced Weight Gain
2013 - Study ~ Obesity-driven synaptic remodeling affects endocannabinoid control of orexinergic neurons
2013 - Study ~ Moderation of antipsychotic-induced weight gain by energy balance gene variants in the RUPP autism network risperidone studies
2013 - Study ~ Orexin neurons use endocannabinoids to break obesity-induced inhibition
2013 - Study ~ Insulin induces long-term depression of ventral tegmental area dopamine neurons via endocannabinoids
2013 - Study ~ Endocannabinoids and obesity.
2013 - Study ~ Fat to treat fat: Emerging relationship between dietary PUFA, endocannabinoids, and obesity.
2013 - Study ~ The endocannabinoid system in obesity
2013 - Study ~ Effects of CB1 receptor blockade on monosodium glutamate induced hypometabolic and hypothalamic obesity in rats.
2013 - Study ~ Activation of type 2 cannabinoid receptors (CB2R) promotes fatty acid oxidation through the SIRT1/PGC-1α pathway.
2013 - Study ~ Analysis of the "endocannabinoidome" in peripheral tissues of obese Zucker rats
2013 - Study ~ Novel effects of the cannabinoid inverse agonist AM 251 on parameters related to metabolic syndrome in obese Zucker rats.
2013 - Study ~ Endocannabinoid crosstalk between placenta and maternal fat in a baboon model (Papiospp.) of obesity.
2013 - Study ~ Monounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase.
2013 - Study ~ Vascular targets for cannabinoids: animal and human studies
2013 - Study ~ Cannabinoids, eating behaviour, and energy homeostasis.
2013 - Study ~ A potential role for GPR55 in the regulation of energy homeostasis.
2013 - Study ~ Effect of high fat-diet and obesity on gastrointestinal motility.
2012 - Study ~ To Be or Not To Be—Obese
2012 - Study ~ Resistance to diet-induced adiposity in cannabinoid receptor-1 deficient mice is not due to impaired adipocyte function.
2012 - Study ~ Cannabinoid Receptor 1 (CNR1) 4895 C/T Genetic Polymorphism was Associated with Obesity in Japanese Men.
2012 - Study ~ Excess
of the endocannabinoid anandamide during lactation induces overweight,
fat accumulation and insulin resistance in adult mice
2012 - Study ~ Dietary linoleic acid elevates endogenous 2-AG and anandamide and induces obesity.
2012 - Study ~ Type 2 Diabetes Associated Changes in the Plasma Non-Esterified Fatty Acids, Oxylipins and Endocannabinoids
2012 - Study ~ Endocannabinoids measurement in human saliva as potential biomarker of obesity.
2012 - Study ~ Gut microbiota and the development of obesity.
2012 - Study ~ CNR1 genotype influences HDL-cholesterol response to change in dietary fat intake.
2012 - Study ~ Hypothalamic CB1 Cannabinoid Receptors Regulate Energy Balance in Mice
2012 - Study ~ Cannabinoid signalling regulates inflammation and energy balance: The importance of the brain-gut axis
2012 - Study ~ Cannabis exposure associated with weight reduction and β-cell protection in an obese rat model.
2012 - Study ~ Cannabinol and cannabidiol exert opposing effects on rat feeding patterns.
2012 - Study ~ The thrifty lipids: endocannabinoids and the neural control of energy conservation.
2012 - Study ~ Photoperiodic
Changes in Endocannabinoid Levels and Energetic Responses to Altered
Signalling at CB1 Receptors in Siberian Hamsters
2012 - Study ~ The potential use of cannabidiol in the therapy of metabolic syndrome
2012 - Study ~ GPR119 as a fat sensor.
2012 - Study ~ Cannabinoid Type 1 Receptor Gene Polymorphism and Macronutrient Intake.
2012 - Study ~ New vistas for treatment of obesity and diabetes? Endocannabinoid signalling and metabolism in the modulation of energy balance.
2012 - Study ~ Fatty acid flux and oxidation are increased by rimonabant in obese women
2011 - Study ~ Resistance to diet-induced adiposity in cannabinoid receptor-1 deficient mice is not due to impaired adipocyte function
2011 - Study ~ Krill oil significantly decreases 2-arachidonoylglycerol plasma levels in obese subjects.
2011 - Study ~ Effect of dietary krill oil supplementation on the endocannabinoidome of metabolically relevant tissues from high-fat-fed mice
2011 - Study ~ Lipid transport function is the main target of oral oleoylethanolamide to reduce adiposity in high-fat-fed mice
2011 - Study ~ Sympathetic activity controls fat-induced oleoylethanolamide signaling in small intestine.
2011 - Study ~ The association of the rs1049353 polymorphism of the CNR1 gene with hypoadiponectinemia.
2011 - Study ~ Gadolinium-HU-308-incorporated micelles.
2011 - Study ~ Adipose tissue endocannabinoid system gene expression: depot differences and effects of diet and exercise
2011 - Study ~ 385 C/A polymorphism of the fatty acid amide hydrolase gene is associated with metabolic syndrome in the Chinese Han population.
2011 - Study ~ Greasing the wheels of managing overweight and obesity with omega-3 fatty acids
2011 - Study ~ Obesity and Cannabis Use: Results From 2 Representative National Surveys
2011 - Study ~ Psychiatric adverse effects of rimonobant in adults with Prader Willi syndrome.
2011 - Study ~ The neutral cannabinoid CB1 receptor antagonist AM4113 regulates body weight through changes in energy intake in the rat.
2011 - Study ~ Effects of Chronic Oral Rimonabant Administration on Energy Budgets of Diet-Induced Obese C57BL/6 Mice.
2011 - Study ~ The role of central CB2 cannabinoid receptors on food intake in neonatal chicks.
2011 - Study ~ The central cannabinoid CB1 receptor is required for diet-induced obesity and rimonabant's antiobesity effects in mice
2010 - Study ~ Alterations in the hippocampal endocannabinoid system in diet-induced obese mice.
2010 - Study ~ Expression of cannabinoid CB1 receptors by vagal afferent neurons: kinetics and role in influencing neurochemical phenotype
2010 - Study ~ Polymorphisms in the endocannabinoid receptor 1 in relation to fat mass distribution
2010 - Study ~ The endocannabinoid system links gut microbiota to adipogenesis
2010 - Study ~ CD36 gene deletion decreases oleoylethanolamide levels in small intestine of free-feeding mice.
2010 - Study ~ A
common CNR1 (cannabinoid receptor 1) haplotype attenuates the decrease
in HDL cholesterol that typically accompanies weight gain.
2010 - Study ~ The Effects of Rimonabant on Brown Adipose Tissue in Rat: Implications for Energy Expenditure
2010 - Study ~ The novel cannabinoid CB1 antagonist AM6545 suppresses food intake and food-reinforced behavior.
2010 - Study ~ Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk in mouse models of obesity.
2010 - Study ~ A
common polymorphism in the cannabinoid receptor 1 (CNR1) gene is
associated with antipsychotic-induced weight gain in Schizophrenia.
2010 - Study ~ Rehashing endocannabinoid antagonists: can we selectively target the periphery to safely treat obesity and type 2 diabetes?
2010 - Study ~ Modulation of Adipocyte Biology by Δ9-Tetrahydrocannabinol
2010 - Study ~ Cannabidiol Attenuates the Appetitive Effects of Δ9-Tetrahydrocannabinol in Humans Smoking Their Chosen Cannabis
2010 - Study ~ Perspectives of CB1 Antagonist in Treatment of Obesity: Experience of RIO-Asia
2010 - Study ~ Deficiency of CB2 cannabinoid receptor in mice improves insulin sensitivity but increases food intake and obesity with age.
2010 - Study ~ Analysis of gene expression pattern reveals potential targets of dietary oleoylethanolamide in reducing body fat gain in C3H mice.
2010 - Study ~ G1359A polymorphism in the cannabinoid receptor-1 gene is associated with metabolic syndrome in the Chinese Han population
2010 - Study ~ Effect of dietary fat on endocannabinoids and related mediators: consequences on energy homeostasis, inflammation and mood.
2010 - Study ~ Cannabis Use and Obesity and Young Adults
2010 - Study ~ The endocannabinoid system modulates the valence of the emotion associated to food ingestion
2009 - Study ~ Synthetic and plant-derived cannabinoid receptor antagonists show hypophagic properties in fasted and non-fasted mice
2009 - Study ~ Cannabinoid CB2 Receptor Potentiates Obesity-Associated Inflammation, Insulin Resistance and Hepatic Steatosis
2009 - Study ~ Biomarkers of Endocannabinoid System Activation in Severe Obesity
2009 - Study ~ The endocanabinnoid system and diabetes - critical analyses of studies conducted with rimonabant
2009 - Study ~ Cannabinoids for clinicians: the rise and fall of the cannabinoid antagonists
2009 - Study ~ Endocannabinoids and Their Receptors as Targets for Obesity Therapy
2009 - Study ~ The endocannabinoid system as a link between homoeostatic and hedonic pathways involved in energy balance regulation
2009 - Study ~ Endocannabinoids and cardiovascular prevention: real progress?
2009 - Study ~ N-acylethanolamines, anandamide and food intake
2009 - Study ~ Effects of cannabinoid drugs on the reinforcing properties of food in gestationally undernourished rats
2009 - Study ~ Anti-inflammatory effect of palmitoylethanolamide on human adipocytes.
2008 - Study ~ Endocannabinoid receptor 1 gene variations increase risk for obesity and modulate body mass index in European populations
2008 - Study ~ GPR119, a novel G protein-coupled receptor target for the treatment of type 2 diabetes and obesity
2008 - Study ~ Activating Parabrachial Cannabinoid CB1 Receptors Selectively Stimulates Feeding of Palatable Foods in Rats
2008 - Study ~ Targeted enhancement of oleoylethanolamide production in proximal small intestine induces across-meal satiety in rats.
2008 - Study ~ Endocannabinoids and the Control of Energy Homeostasis
2008 - Study ~ The lipid messenger OEA links dietary fat intake to satiety.
2008 - Study ~ The Role of Adipocyte Insulin Resistance in the Pathogenesis of Obesity-Related Elevations in Endocannabinoids
2008 - Study ~ The discovery of taranabant, a selective cannabinoid-1 receptor inverse agonist for the treatment of obesity.
2008 - Study ~ Dysregulation of peripheral endocannabinoid levels in hyperglycemia and obesity: Effect of high fat diets.
2008 - Study ~ Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects
2008 - Study ~ Endocannabinoids and the neurochemistry of gluttony
2008 - Study ~ Dysregulation of peripheral endocannabinoid levels in hyperglycemia and obesity: Effect of high fat diets.
2008 - Study ~ Dysregulation of the endocannabinoid system in obesity.
2008 - Study ~ Cholesterol-induced stimulation of platelet aggregation is prevented by a hempseed- enriched diet
2008 - Study ~ Inhibitory effect of the anorexic compound oleoylethanolamide on gastric emptying in control and overweight mice.
2007 - Study ~ Identification of Endocannabinoids and Related Compounds in Human Fat Cells
2007 - Study ~ Genetic variations at the endocannabinoid type 1 receptor gene (CNR1) are associated with obesity phenotypes in men
2007 - Study ~ The endogenous cannabinoid system: a new player in the brain-gut-adipose axis
2007 - Study ~ No
evidence for an involvement of variants in the cannabinoid receptor
gene (CNR1) in obesity in German children and adolescents.
2007 - Study ~ Immune-mediated Activation of the Endocannabinoid System in Visceral Adipose Tissue in Obesity
2006 - Study ~ Dysregulation of the Peripheral and Adipose Tissue Endocannabinoid System in Human Abdominal Obesity
2006 - Study ~ AM
251 produces sustained reductions in food intake and body weight that
are resistant to tolerance and conditioned taste aversion
2006 - Study ~ Weight Control in Individuals With Diabetes
2006 - Study ~ The emerging role of the endocannabinoid system in endocrine regulation and energy balance.
2006 - Study ~ Does Cannabis Hold the Key to Treating Cardiometabolic Disease
2006 - Study ~ The impact of obesity on reproduction in women with polycystic ovary syndrome.
2006 - Study ~ Human adipose tissue binds and metabolizes the endocannabinoids anandamide and 2-arachidonoylglycerol.
2005 - Study ~ Activation of the Peripheral Endocannabinoid System in Human Obesity
2005 - Study ~ Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity
2005 - Study ~ Food for thought: endocannabinoid modulation of lipogenesis
2005 - Study ~ Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity
2005 - Study ~ Endocannabinoids and food intake: newborn suckling and appetite regulation in adulthood.
2005 - Study ~ Endocannabinoids in the Regulation of Appetite and Body Weight.
2004 - Study ~ CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity
2003 - Study ~ The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis
2003 - Study ~ Short-term fasting and prolonged semistarvation have opposite effects on 2-AG levels in mouse brain.
2000 - Study ~ Low dose anandamide affects food intake, cognitive function, neurotransmitter and corticosterone levels in diet-restricted mice.