JWH-015 (a synthetic CB2 & GPR-55 agonist) & Cannabis studies completed
Overview
Science and Research
2012 - Study ~ Contrasting protective effects of cannabinoids against oxidative stress and amyloid-β evoked neurotoxicity in vitro.
2012 - Study ~ Cannabinoids and muscular pain. Effectiveness of the local administration in rat.
2012 - Study ~ Cannabinoid receptor 2 agonist ameliorates mesenteric angiogenesis and portosystemic collaterals in cirrhotic rats.
2011 - Study ~ Crosstalk between Chemokine Receptor CXCR4 and Cannabinoid Receptor CB(2) in Modulating Breast Cancer Growth and Invasion.
2011 - Study ~ Marijuana-based Drugs: Innovative Therapeutics or Designer Drugs of Abuse?
2011 - Study ~ Beyond THC: The New Generation of Cannabinoid Designer Drugs.
2011 - Study ~ Crosstalk between chemokine receptor CXCR4 and cannabinoid receptor CB2 in modulating breast cancer growth and invasion.
2011 - News ~ Latest blood test detects 12 popular synthetic cannabinoids in "fake pot".
2011 - News ~ Chemicals Used in "Spice" and "K2" Type Products Now Under Federal Control and Regulation
2010 - Study ~ Protective effects of the synthetic cannabinoids CP55,940 and JWH-015 on rat brain mitochondria upon paraquat exposure.
2010 - News ~ Now, There's a Test for That -- Norchem's "Fake Marijuana" Test Reveals Significantly Increased Abuse of Spice/K2
2009 - Study - Inhibition of human tumour prostate PC-3 cell growth by cannabinoids R(+)-Methanandamide and JWH-015: Involvement of CB2
2009 - Study - The activation of cannabinoid CB2 receptors stimulates in situ and in vitro beta-amyloid removal by human macrophages
2008 - Study ~ CB2 cannabinoid receptor agonist JWH-015 modulates human monocyte migration through defined intracellular signaling pathways.
2008 - Study ~ Behavioral effects of CB2 cannabinoid receptor activation and its influence on food and alcohol consumption.2007 - Study ~ Potential role for CB2 selective ligands as immunosuppressive agents
2007 - Study ~ Opposing control of cannabinoid receptor stimulation on amyloid-beta-induced reactive gliosis: in vitro and in vivo evidence.
2007 - Study ~ Spinal cannabinoid receptor type 2 activation reduces hypersensitivity and spinal cord glial activation after paw incision.
2006 - Study ~ CB2
cannabinoid receptor agonist, JWH-015 triggers apoptosis in immune
cells: Potential role for CB2 selective ligands as immunosuppressive
agents
2005 - Study ~ Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation
2005 - Study ~ CB2 cannabinoid receptors in trabecular meshwork cells mediate JWH015-induced enhancement of aqueous humor outflow facility.
2005 - Study ~ Avoidance
of Abeta[(25-35)] / (H(2)O(2)) -induced apoptosis in lymphocytes by the
cannabinoid agonists CP55,940 and JWH-015 via receptor-independent and
PI3K-dependent mechanisms: role of NF-kappaB and p53.
2002 - Study ~ Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease