HU-210- a synthetic cannabinoid & Cannabis studies completed
Overview
HU-210 is 100 to 800 times more potent than natural THC from cannabis and has an extended duration of action. HU-210 is the (-)-1,1-dimethylheptyl analog of 11-hydroxy- delta 8- tetrahydrocannabinol; in some references it is called 1,1-dimethylheptyl- 11-hydroxytetrahydrocannabinol.
The abbreviation "HU" stands for Hebrew University.
Science and Research
2012 - Study ~ Contrasting effects of different cannabinoid receptor ligands on mouse ingestive behavior.
2012 - Study ~ Long-term use of HU210 adversely affects spermatogenesis in rats by modulating the endocannabinoid system.
2012 - Study ~ The spice in France: mixed herbs containing synthetic cannabinoids.
2011 - Study ~ The potential for clinical use of cannabinoids in treatment of cardiovascular diseases.
2011 - Study ~ Beyond THC: The New Generation of Cannabinoid Designer Drugs.
2011 - Study ~ Investigating a not-so-natural high.
2011 - Study ~ Regulation of nausea and vomiting by cannabinoids.
2011 - Study ~ Cannabinoid
Receptor Type 1 Protects Nigrostriatal Dopaminergic Neurons against
MPTP Neurotoxicity by Inhibiting Microglial Activation
2011 - Study ~ The
effects of cannabinoid drugs on abnormal involuntary movements in
dyskinetic and non-dyskinetic 6-hydroxydopamine lesioned rats.
2010 - Study ~ Involvement of cannabinoid-1 and cannabinoid-2 receptors in septic ileus.
2010 - Study ~ Antitumorigenic Effects of Cannabinoids beyond Apoptosis
2010 - Study ~ Regulation of nausea and vomiting by cannabinoids
2009 - Study - Spice drugs: cannabinoids as a new designer drugs
2009 - Study ~ Cannabinoid receptor 1 is a potential drug target for treatment of translocation-positive rhabdomyosarcoma2008 - Study ~ Repeated Cannabinoid Injections into the Rat Periaqueductal Gray Enhances Subsequent Morphine Antinociception
2007 - Study ~ Cannabinoids Induce Glioma Stem-like Cell Differentiation and Inhibit Gliomagenesis
2007 - Study ~ The synthetic cannabinoid HU210 induces spatial memory deficits and suppresses hippocampal firing rate in rats
2007 - Study ~ The synthetic cannabinoids attenuate allodynia and hyperalgesia in a rat model of trigeminal neuropathic pain.
2007 - Study - The synthetic cannabinoid HU-210 attenuates neural damage in diabetic mice and hyperglycemic pheochromocytoma PC12 cells
2007 - Study - Cannabinoids Ameliorate Pain and Reduce Disease Pathology in Cerulein-Induced Acute Pancreatitis
2007 - Study ~ Arthritis and cannabinoids: HU-210 and Win-55,212-2 prevent IL-1alpha-induced matrix degradation in bovine articular chondrocytes in-vitro.2006 - Study ~ Actions of the FAAH inhibitor URB597 in neuropathic and inflammatory chronic pain models
2005 - Study - Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects
2005 - Study ~ Direct cerebrovascular effects of CB1 receptor activation by the synthetic endocannabinoid HU-210 in vivo
2005 - Study ~ Cannabinoids provide neuroprotection against 6-hydroxydopamine toxicity in vivo and in vitro: relevance to Parkinson's disease.
2005 - News - Marijuana May Spur New Brain Cells
2005 - News - Study Shows Marijuana Promotes Neuron Growth
2005 - News ~ Is cannabis good for your brain?
2005 - News ~ Surprising Brain Effects From Pot-Like Drug
2005 - News ~ Marijuana might cause new cell growth in the brain2004 - Study ~ The endogenous cannabinoid system protects against colonic inflammation
2004 - News ~ Cannabinoids spell relief in colon inflammation
2003 - Study ~ Inhibition of tumor angiogenesis by cannabinoids
2002 - Study ~ Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease
2002 - Study ~ Influence
of the CB1 receptor antagonist, AM 251, on the regional haemodynamic
effects of WIN-55212-2 or HU 210 in conscious rats
2002 - Study ~ Activation of cannabinoid receptors decreases the area of ischemic myocardial necrosis.
2002 - Study ~ Increase
of the heart arrhythmogenic resistance and decrease of the myocardial
necrosis zone during activation of cannabinoid receptors
2000 - Study ~ Suppression
of Nerve Growth Factor Trk Receptors and Prolactin Receptors by
Endocannabinoids Leads to Inhibition of Human Breast and Prostate Cancer
Cell Proliferation
2000 - Study ~ Effects
of cannabinoid receptor agonists on neuronally-evoked contractions of
urinary bladder tissues isolated from rat, mouse, pig, dog, monkey and
human.
2000 - Study ~ Involvement
of central and peripheral cannabinoid receptors in the regulation of
heart resistance to arrhythmogenic effects of epinephrine.
2000 - Study ~ Histamine induced responses are attenuated by a cannabinoid receptor agonist in human skin.
2000 - Study ~ Increased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon
2000 - Study ~ Inhibitory effects of the cannabinoid agonist HU 210 on rat sexual behaviour.1999 - Study ~ Learning impairment produced in rats by the cannabinoid agonist HU 210 in a water-maze task.