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HEPATITIS & Cannabis studies completed  from 2001 to 2013


Hepatitis is swelling and inflammation of the liver. It is not a condition, but is often used to refer to a viral infection of the liver.

Some people have no symptoms whereas others develop yellow discoloration of the skin and whites of the eyes, poor appetite, vomiting, tiredness, abdominal pain, or diarrhea. Hepatitis may be temporary (acute) or long term (chronic) depending on whether it lasts for less than or more than six months.

Acute hepatitis can sometimes resolve on its own, progress to chronic hepatitis, or rarely result in acute liver failure. Over time the chronic form may progress to scarring of the liver, liver failure, or liver cancer.

The most common cause worldwide is viruses. Other causes include heavy alcohol use, certain medications, toxins, other infections, autoimmune diseases, and non-alcoholic steatohepatitis (NASH)

Science & Medical Journals

2013 - Study ~ Marijuana Smoking Does Not Accelerate Progression of Liver Disease in HIV-Hepatitis C Coinfection: A Longitudinal Cohort Analysis.

2013 - Study ~ Cannabinoid receptor 2 counteracts interleukin-17-induced immune and fibrogenic responses in mouse liver

2013 - Study ~ US Patent Application 20130171145 - METHODS OF TREATING LIVER DISEASE

2012 - Study - Spain - Prevention of Fibrosis Progression in CCl4-Treated Rats: Role of the Hepatic Endocannabinoid and Apelin Systems. source: Dr. Wladimiro Jiménez, Servicio de Bioquímica y Genética Molecular, Hospital Clinic University, Villarroel 170, Barcelona 08036, Spain. E-mail:

2012 - Study ~ The endocannabinoid N-arachidonoyl dopamine (NADA) selectively induces oxidative stress-mediated cell death in hepatic stellate cells but not in hepatocytes

2012 - Study ~ Serum Metabolic Profiling Study of Hepatocellular Carcinoma Infected with Hepatitis B or Hepatitis C Virus by Using Liquid Chromatography-Mass Spectrometry.

2011 - Study - USA?  Cannabidiol causes activated hepatic stellate cell death through a mechanism of endoplasmic reticulum stress-induced apoptosis. source: Cell Death and Disease

2011 - Study ~  Endocannabinoids in liver disease.

2011 - Study - USA - Role of Myeloid-Derived Suppressor Cells in Amelioration of Experimental Autoimmune Hepatitis Following Activation of TRPV1 Receptors by Cannabidiol. source: US National Library of Medicine

2011 - News -  USA - Cannabis Compound Induces Death Of Cells Associated With Liver Fibrosis. source: NORML, New York. Email Paul Armentano, NORML Deputy Director, at:

2009 - Study ~ The role of CB2 cannabinoid receptor and Leptin in hepatic fibrosis via lymphocyte alterations and HSC phagocytosis.

2009 - Study ~  Use of Cannabinoids as a Novel Therapeutic Modality Against Autoimmune Hepatitis.

2009 - News ~ Medical Marijuana and Viral Hepatitis.

2009 - News ~ Medical Marijuana and Hepatitis C.

2009 - Study ~ Cannabinoids as novel anti-inflammatory drugs

2009 - Patent - USA ~ Patent Application 20090005461 - Use of Cannabidiol in the Treatment of Hepatitis

2008 - Study - USA - Attenuation of Experimental Autoimmune Hepatitis by Exogenous and Endogenous Cannabinoids source: Department of Pathology, Microbiology, and Immunology, School of Medicine, University of South Carolina, Columbia, South Carolina (V.L.H., S.H., M.N., P.S.N.); The Skaggs Institute for Chemical Biology and Departments of Cell Biology and Chemistry, The Scripps Research Institute, La Jolla, California (B.F.C.); and Department of Pharmaceutical and Biomedical Sciences, College of Pharmacy, University of South Carolina, Columbia, South Carolina (L.J.H.)

  1. Address correspondence to:
    Dr. Prakash S. Nagarkatti, Department of Pathology, Microbiology, and Immunology, University of South Carolina School of Medicine, 6439 Garners Ferry Rd., Columbia, SC 29209. E-mail:

2008 - Study ~ Endocannabinoids and Liver Disease. III. Endocannabinoid effects on immune cells: implications for inflammatory liver diseases.

2008 - Study - Canada - Evaluation of oral cannabinoid-containing medications for the management of interferon and ribavirin-induced anorexia, nausea and weight loss in patients treated for chronic hepatitis C virus source: Canadian Journal of Gastrology

2008 - Study ~ Regression of Fibrosis after Chronic Stimulation of Cannabinoid CB2 Receptor in Cirrhotic Rats.

2008 - Study ~ Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects.

2008 - Study ~  Endocannabinoids in liver disease and hepatic encephalopathy.

2006 - Study - USA - Cannabis use improves retention and virological outcomes in patients treated for hepatitis C source: Department of Medicine, University of California, San Francisco, California.

2006 - News - USA - Pot Helps Hepatitis Treatment
source: Josh Richman, The Oakland Tribune.

2005 - Study - Mexico ~ The endocannabinoid system in chronic liver disease. source: Annals of Hepatology.

2003 - Study - USA - Moderate Cannabis Use Associated with Improved Treatment Response in Hepatitis C Patients on Methadone source: Wiley Online Library

2003 - Study - Israel - A Novel Synthetic Cannabinoid Derivative Inhibits Inflammatory Liver Damage via Negative Cytokine Regulation. source: Molecular Pharmacology Dr. Iris Lavon, Pharmos LTD, Kiryat Weizmann, Bld #13b, Rehovot 76326, Israel. E-mail:

2001 - Personal - USA - Hepatitis C - The Silent Killer Can Medical Cannabis Help? source: Jay R. Cavanaugh, PhD

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