Can Cannabis be Beneficial in Preventing Heart Disease?
Overview
- Heart disease describes a range
of conditions that affect your heart.
- Diseases under the heart disease umbrella include blood vessel diseases, such as coronary artery disease; heart rhythm problems (arrhythmias); and heart defects you're born with (congenital heart defects), among others.
- The term "heart disease" is often used interchangeably with the term "cardiovascular disease."
- Cardiovascular
disease generally refers to conditions that involve narrowed or
blocked blood vessels that can lead to a heart attack, chest pain
(angina) or stroke.
- Other heart conditions, such as those that affect
your heart's muscle, valves or rhythm, also are considered forms of
heart disease.
- Many forms of heart disease can be prevented or treated with healthy lifestyle choices.
2020 - Abstract Study ~ USA: Marijuana in pediatric and adult congenital
heart disease heart transplant listing: A survey of provider practices
and attitudes.
Pediatric Transplantation.
2020 - Full Study ~ USA: Marijuana use and coronary artery disease in young adults.
Medical University of South Carolina.
2020 - Full Study ~ UK: Rates, Predictors and the Impact Cannabis
Misuse on In-hospital Outcomes Among Patients Undergoing Percutaneous
Coronary Intervention.
Clinical Practice.
2019 - Full Study ~ USA: Review of the many faces of synthetic cannabinoid toxicities.
Mental Health Clinician.
2019 - Full Study ~ Canada: International Perspectives on the Implications of Cannabis Legalization:
A Systematic Review & Thematic Analysis.
Enviromental Research & Public Health.
2019 - Full Study ~ Poland: Sex differences in distribution of cannabinoid receptors (CB1 and CB2),
S100A6 and CacyBP/SIP in human ageing hearts.
Biology of Sex Differences.
2019 - Full Study ~ Saudi Arabia: Cannabinoids for Treating Cardiovascular Disorders: Putting Together a Complex Puzzle.
King Abdulaziz University.
2019 - Full Study ~ USA: Will Mary Jane Leave You Heartbroken? Marijuana Use and Risk of Takotsubo Cardiomyopathy.
Cureus.
2019 - Full Study ~ Canada: Activation of Cannabinoid Receptors
Attenuates Endothelin-1-induced Mitochondrial Dysfunction in Rat
Ventricular Myocytes.
Journal of Cardiovascular Pharmacology.
2019 - Full Study ~ USA: Occurrence of Takotsubo Cardiomyopathy after Synthetic Cannabinoid Consumption.
2019 - Full Study ~ Germany: Endocannabinoid 2-arachidonoylglycerol is elevated in the coronary circulation during acute coronary syndrome.
Pneumology.
2019 - Full Study ~ UK: Omega-3 polyunsaturated fatty acids impinge on CD4+ T cell motility and adipose tissue distribution via direct and lipid mediator-dependent effects.
Cardiovascular Research.
2019 - Full Study ~ Canada: An overview of the adverse effects of cannabis use for Canadian physicians.
Clinical and Investigative Medicine.
2019 - Full Study ~ Sweeden: ADHD Symptoms as a Potential Driver to Cannabis Use in Young Persons
With Complex Congenital Heart Defects.
Canadian Journal of Cardiology.
2019 - Full Study ~ Peru / USA: Vertebral Artery Dissection and Takotsubo Syndrome Associated with Marijuana Use.
Cureus.
2019 - Abstract Study ~ Ukraine: Cannabinoids and Cardiovascular System.
2019 - Abstract Study ~ Canada: The Risk of Cardiovascular
Events on Cannabis’ Highest Day.
Canadian Journal of Cardiology.
2019 - Abstract Study ~ Turkey: Osborn wave and new-onset atrial
fibrillation related to hypothermia after synthetic cannabis (bonsai)
abuse.
Archives of the Turkish Society of Cardiology.
2019 - Abstract Study ~ USA: Recurrent Cardiogenic Shock Associated with Cannabis Use: Report of a Case and Review of the Literature.
Journal of Emergency Medicine.
2019 - Abstract Study ~ Germany: Cannabinoid-sensitive receptors in cardiac physiology and ischaemia.
2019 - Abstract Study ~ USA: Performance and Health-Related Characteristics of Physically Active Males Using Marijuana.
Journal of Strength and Conditioning Research.
2019 - Abstract Study ~ USA: Cannabis and Cardiovascular Disease.
Current Atherosclerosis Reports.
2019 - Abstract Study ~ Iran: The protective mechanism of cannabidiol in cardiac injury: A systematic review of non- clinical studies.
Current Pharmaceutical Design.
2019 - Abstract Study ~ Germany / Spain: Salivary endocannabinoids as mediators in
the relationship between omega-6 and omega- 3 fatty acid ratio intake
from highly-processed foods and anthropometric markers of health in
women.
2019 - Abstract Study ~ Brazil: Role of the endocannabinoid system in the
dorsal hippocampus in the cardiovascular changes and delayed
anxiety-like effect induced by acute restraint stress in rats.
Journal of Psychopharmacology.
2019 - Abstract Study ~ Canada / Italy: Role of the endocannabinoidome in human and mouse atherosclerosis.
Current Pharmaceutical Design.
2019 - Abstract Study ~ Poland: Fatty acid amide hydrolase inhibitor
(URB597) as a regulator of myocardial lipid metabolism in spontaneously
hypertensive rats.
2019 - Abstract Study ~ China: Monoacylglycerol Lipase Inactivation by
Using URB602 Mitigates Myocardial Damage in a Rat Model of Cardiac
Arrest.
Critical Care Journal.
2019 - Abstract Study ~ Germany: CB2-deficiency is associated with a
stronger hypertrophy and remodeling of the right ventricle in a murine
model of left pulmonary artery occlusion.
2019 - Abstract Study ~ Canada / USA: Acute and residual effects of smoked
cannabis: Impact on driving speed and lateral control, heart rate, and
self-reported drug effects.
2019 - Abstract Study ~ Italy: A case report positive for synthetic
cannabinoids: are cardiovascular effects related to their protracted
use?
2019 - Abstract Study ~ India: Ameliorative effects of hempseed (Cannabis
sativa) against hypercholesterolemia associated cardiovascular changes.
2019 - Abstract Study ~ Canada: Marijuana Lollipop-Induced Myocardial Infarction.
2019 - Abstract Study ~ Turkey: The ameliorating effect of cannabinoid type
2 receptor activation on brain, lung, liver and heart damage in cecal
ligation and puncture-induced sepsis model in rats.
2019 - Abstract Study ~ Netherlands / USA / Hungary /
Poland: Activity-based protein profiling of the
human failing ischemic heart reveals alterations in hydrolase activities
involving the endocannabinoid system.
2019 - Abstract Study ~ Australia: The effect of high maternal linoleic acid on endocannabinoid signalling in rodent hearts.
Journal of Developmental Origins of Health and Disease.
2018 - Full Study ~ Netherlands: Caloric restriction lowers endocannabinoid tonus and improves cardiac function in type 2 diabetes.
Nutrition & Diabetes.
2018 - Full Study ~ USA: Retrospective Chart Review of Synthetic Cannabinoid Intoxication with Toxicologic
Analysis.
Western Journal of Emergency Medicine.
2018 - Full Study ~ Poland / Germany: Cannabinoids in arterial, pulmonary and portal hypertension – mechanisms of action and potential therapeutic significance.
British Journal of Pharmacology.
2018 - Full Study ~ France: A Systematic Review of the Complex Effects of Cannabinoids on Cerebral and Peripheral Circulation in Animal Models.
Frontiers in Physiology.
2018 - Full Study ~ USA: Pediatric Death Due to Myocarditis After Exposure to Cannabis.
Clinical Practice and Cases in Emergency Medicine.
2018 - Full Study ~ USA: Cannabinoids, the Heart of the Matter.
Journal of the American Heart Association.
2018 - Full Study ~ Denmark: Interaction between warfarin and cannabis.
Basic & Clinical Pharmacology & Toxicology.
2018 - Full Study ~ Belgium: Coronary vasospasm complicating cannabinoid hyperemesis syndrome.
Journal of Cardiology Cases.
2018 - Full Study ~ USA / Curacau / Russia: Primary Causes of Hospitalizations and Procedures, Predictors of
In-hospital Mortality, and Trends in Cardiovascular and Cerebrovascular
Events Among Recreational Marijuana Users: A Five-year Nationwide
Inpatient Assessment in the United States.
Cureus.
2018 - Full Study ~ USA: Cannabis Use Disorder in Young Adults with Acute Myocardial Infarction:
Trend Inpatient Study from 2010 to 2014 in the United States.
Cureus.
2018 - Full Study ~ USA: Plasma fatty acid ethanolamides are associated with postprandial triglycerides, ApoCIII and ApoE in humans consuming high fructose corn syrup-sweetened beverage.
American Journal of Physiology Endocrinology & Metabolism.
2018 - Full Study ~ USA: The Spice of Life…and Death: A Case Presentation and Review of Synthetic Marijuana Use in Mississippi.
Journal of the Mississiippi State Medical Association.
2018 - Full Study ~ USA: Marijuana Induced Type I Brugada Pattern: A Case Report.
American Journal of Medical Case Reports.
2018 - Full Study ~ USA: Clinical Characteristics and Angiographic Findings of Acute Myocardial
Infarction Associated With Marijuana Use: Consecutive Case Series.
SciFed Journal of Cardiology.
2018 - Full Study ~ Nepal / USA: A Systematic Review of Marijuana Use and Outcomes in Patients with Myocardial Infarction.
Cureus.
2018 - Full Study ~ USA: Hypothesis: Clues From Mammalian Hibernation for Treating Patients With Anorexia Nervosa.
Frontiers in Psychology.
2018 - Full Study ~ USA: The Endocannabinoid System and Heart Disease: The Role of Cannabinoid Receptor Type 2.
Cardiovascular & Hematological Disorders - Drug Targets.
2018 - Full Study ~ Brazil: Medial prefrontal cortex TRPV1 and CB1 receptors modulate cardiac
baroreflex activity by regulating the NMDA receptor/nitric oxide
pathway.
American Journal of Physiology.
2018 - Full Study ~ Argentina: Anandamide and endocannabinoid system: an attractive therapeutic approach for cardiovascular disease.
Therapeutic Advances in Cardiovascular Disease.
2018 - Full Study ~ USA: Feasibility Evaluation of Myocardial Cannabinoid Type 1 Receptor Imaging
in Obesity: A Translational Approach.
2018 - Full Study ~ USA: Endocannabinoid Virodhamine is an Endogenous Inhibitor of Human Cardiovascular CYP2J2 Epoxygenase.
Biochemistry.
2018 - Full Study ~ USA: Coma, Seizures, Atrioventricular Block, and Hypoglycemia in an ADB-FUBINACA Body-Packer.
Journal if Emergency Medicine.
2018 - Full Study ~ USA: Burden of arrhythmia in recreational marijuana users.
International Journal of Cardiology .
2018 - Full Study ~ USA: Relation of Cannabis Use and Atrial Fibrillation Among Patients Hospitalized for Heart Failure.
The American Journal of Cardiology.
2018 - Full Study ~ USA: Associations between cannabis use and cardiometabolic risk factors: A longitudinal study of men.
Psychosomatic Medicine.
2018 - Full Study ~ USA: Marijuana use and short-term outcomes in patients hospitalized for acute myocardial infarction.
Departmentof Medicine, Division of Cardiology, Universityof Colorado.
2018 - Full Study ~ Turkey: Speckle-tracking strain assessment of left ventricular dysfunction in
synthetic cannabinoid and heroin users.
The Anatolian Journal of Cardiology.
2018 - Abstract Study ~ USA / Pakistan: Pseudo-Wellens’ syndrome secondary to concurrent cannabis and phencyclidine intoxication.
BMJ Journals.
2018 - Abstract Study ~ Turkey: How much can synthetic cannabinoid damage the heart? A case of
cardiogenic shock following resistant ventricular fibrillation after
synthetic cannabinoid use.
Journal of Clinical Ultrasound.
2018 - Abstract Study ~ USA: Ischaemic cardiomyopathy and embolic stroke in a young adult with suspected synthetic cannabinoid use.
BMJ Case Reports.
2018 - Abstract Study ~ USA: Marijuana-associated ST-elevation myocardial infarction: is this a benign drug.
BMJ Case Reports.
2017 - Full Study ~ Sweden / Italy / UK / Finland / Netherlands / France: Increased Levels of Circulating Fatty Acids Are Associated with
Protective Effects against Future Cardiovascular Events
Journal of Proteome Research.
2017 - Abstract Study ~ UK / Canada: The Placebo Effect in Cardiology: Understanding and Using It.
Canadian Journal of Cardiology.
2017 - Full Study ~ USA / Barbados: Did Cannabis Precipitate an STEMI in a Young Woman?
Cardiology Research.
2017 - Full Study ~ Giant J (Osborn) Wave due to Bonsai Abuse: Comments on Clinical Practice.
Balkan Medical Journal.
2017 - Full Study ~ UK: In Vivo Cannabidiol Treatment Improves Endothelium-Dependent Vasorelaxation in Mesenteric Arteries of Zucker Diabetic Fatty Rats.
Frontiers in Pharmacology.
2017 - Full Study ~ Italy / USA: Anti-Inflammatory and Neuroprotective Effects of Co-UltraPEALut in a Mouse Model of Vascular Dementia.
Frontiers in Neurology.
2017 - Full Study ~ China: Activation of Endocannabinoid Receptor 2 as a Mechanism of Propofol Pretreatment- Induced Cardioprotection against Ischemia-Reperfusion Injury in Rats.
Oxidative Medicine & Cellular Longevity.
2017 - Full Study ~ China: Activation of cannabinoid receptor type II by AM1241 protects adipose-derived mesenchymal stem cells from oxidative damage and enhances their therapeutic efficacy in myocardial infarction mice via Stat3 activation.
Oncotarget Open Access Journal.
2017 - Full Study ~ Germany: N-Arachidonoyl Dopamine: A Novel Endocannabinoid and Endovanilloid with Widespread Physiological and Pharmacological Activities.
Cannabis & Cannabidiol Research.
2017 - Full Study ~ USA: Precision Nutrition and Omega-3 Polyunsaturated Fatty Acids: A Case for Personalized Supplementation Approaches for the Prevention and Management of Human Diseases.
Nutrients.
2017 - Full Study ~ Korea: Pain medication and long QT syndrome.
Korean Journal of Pain.
2017 - Full Study ~ USA: To Dab or Not to Dab: Rising Concerns Regarding the Toxicity of Cannabis Concentrates.
Cureus.
2017 - Full Study ~ USA: Recreational Marijuana Use and Acute Myocardial Infarction: Insights from Nationwide Inpatient Sample in the United States.
Cureus.
2017 - Full Study ~ China: Extract of Fructus Cannabis Ameliorates Learning and Memory Impairment
Induced by D-Galactose in an Aging Rats Model.
Evidence-Based Complementary and Alternative Medicine.
2017 - Full Study ~ USA: Myocardial Ischemia with Cannabinoid Use in an Adolescent.
2017 - Full Study ~ Poland: Chronic inhibition of fatty acid amide hydrolase by URB597 produces differential effects on cardiac performance in normotensive and hypertensive rats.
British Journal of Pharmacology.
2017 - Full Study ~ USA: Synthetic cannabinoids found in “spice” products alter body temperature and cardiovascular parameters in conscious male rats.
Journal of Drug & Alcohol Abuse.
2017 - Full Study ~ Hungary: Control of myogenic tone and agonist induced contraction of intramural coronary resistance arterioles by cannabinoid type 1 receptors and endocannabinoids.
Prostaglandins & Other Lipid Mediators.2017 - Full Study ~ USA: Pharmacological challenge studies with acute psychosocial stress.
Psychoneuroendocrinology.
2017 - Full Study ~ Netherlands: 2-Arachidonoylglycerol ameliorates inflammatory stress-induced insulin resistance in cardiomyocytes.
Journal of Biological Chemistry.
2017 - Full Study ~ Italy / Belgium / Germany / Netherlands / UK: Pericardial Adipose Tissue Regulates Granulopoiesis, Fibrosis and Cardiac Function After Myocardial Infarction.
Circulation.
2017 - Full Study ~ Greece: Exercise versus targeting of endocannabinoid system for atheromatic plaque stabilization. Opposing or complementary roles?
Hellenic Journal of Cardiology.
2017 - Full Study ~ Germany / USA: Cardiovascular effects of marijuana and synthetic cannabinoids: the good, the bad, and the ugly.
2017 - Full Study ~ Canada: Cannabinoid signaling in health and disease.
Canadian Journal of Physiology and Pharmacology.
2017 - Full Study ~ UK: Human Toxicity Caused by Indole and Indazole Carboxylate Synthetic Cannabinoid Receptor Agonists: From Horizon Scanning to Notification.
Clinical Chemistry.
2017 - Full Study ~ China: Endocannabinoid 2-arachidonoylglycerol protects inflammatory insults from sulfur dioxide inhalation via cannabinoid receptors in the brain.
Journal of Environmental Sciences.
2017 - Abstract Study ~ UK / Canada: Cannabinoids in the Cardiovascular System.
Recent Advances in Cannabinoid Physiology and Pathology.
2017 - Abstract Study ~ China: Supraventricular tachycardia and acute confusion following ingestion of e-cigarette fluid containing AB-FUBINACA and ADB-FUBINACA: a case report with quantitative analysis of serum drug concentrations.
Chinease Journal of Contemporary Pediatrics.
2017 - Abstract Study ~ USA: Cannabis Smoking and Cardiovascular Health: It’s Complicated.
Clinical Pharmacology & Therapeutics.
2017 - Abstract Study ~ Poland: The effects of chronic FAAH inhibition on myocardial lipid metabolism in normotensive and DOCA-salt hypertensive rats.
Life Sciences.2017 - Abstract Study ~ Turkey: Electrocardiographic alterations in patients consuming synthetic cannabinoids.
Journal of Psychopharmacology.
2017 - Abstract Study ~ Taiwan: Indoxyl sulfate upregulates the cannabinoid type 1 receptor gene via an ATF3/c-Jun complex-mediated signaling pathway in the model of uremic cardiomyopathy.
International Journal of Cardiology.
2017 - Abstract Study ~ USA / Australia / Spain: The endocannabinoid system in cardiovascular function: novel insights
and clinical implications.
Clinical Autonomic Research.
2017 - Abstract Study ~ Taiwan: Indoxyl sulfate upregulates the cannabinoid type 1 receptor gene via an ATF3/c-Jun complex-mediated signaling pathway in the model of uremic cardiomyopathy.
International Journal of Cardiology.
2016 - Full Study ~ UK: Acute myocardial infarction, associated with the use of a synthetic adamantyl- cannabinoid: a case report. (UK) (full – 2016) http://bmcpharmacoltoxicol.biomedcentral.com/articles/10.1186/s40360-016-0045-1
2016 - Full Study ~ New Zealand: Chest pain, troponin rise, and ST-elevation in an adolescent boy
following the use of the synthetic cannabis product K2. (New Zealand)
(full – 2016) http://www.annalspc.com/article.asp?issn=0974-2069;year=2016;volume=9;issue=1;spage=79;epage=81;aulast=Zaleta
2016 - Full Study ~ USA: Metabolic Syndrome Among Marijuana Users in the United States: An
Analysis of National Health and Nutrition Examination Survey Data .
(USA) (full – 2016) http://www.amjmed.com/article/S0002-9343(15)01024-4/fulltext
2016 - Full Study ~ USA: A Curious Case of Inhalation Fever Caused by Synthetic Cannabinoid. (USA) (full – 2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917070/
2016 - Full Study ~ Germany: Inhibition of interleukin-1β-induced endothelial tissue factor
expression by the synthetic cannabinoid WIN 55,212-2. (Germany) (full –
2016) http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path%5B%5D=11367&path%5B%5D=35984
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2016 - Full Study ~ Activation of Cannabinoid Receptor Type II
by AM1241 Ameliorates Myocardial Fibrosis via Nrf2-Mediated Inhibition
of TGF-β1/Smad3 Pathway in Myocardial Infarction Mice (China) (full –
2016) http://www.karger.com/Article/FullText/447855
2016 - Full Study ~ The endocannabinoid anandamide causes endothelium-dependent vasorelaxation in human mesenteric arteries. (UK) (full – 2016) http://www.sciencedirect.com/science/article/pii/S104366181630113X
2016 - Full Study ~ Components of the cannabinoid system in the dorsal periaqueductal gray are related to resting heart rate. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982395/
2016 - Full Study ~ CB1 receptor activation in the rat paraventricular nucleus induces
bi-directional cardiovascular effects via modification of glutamatergic
and GABAergic neurotransmission. (Poland/ Germany) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5203819/
2016 - Full Study ~ Cannabinoid CB1 Receptors Are Localized in Striated Muscle Mitochondria
and Regulate Mitochondrial Respiration. (Spain/ France/ Canada) (full –
2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078489/
2016 - Full Study ~ Cannabidiol limits Tcell-mediated chronic autoimmune myocarditis:
implications to autoimmune disorders and organ transplantation. (USA/
Taiwan/ Hungary/ Switzerland/ Israel) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004721/
2016 - Full Study ~ Monoglyceride lipase deficiency modulates endocannabinoid signaling and
improves plaque stability in ApoE-knockout mice. (Austria) (full – 2016)
http://www.sciencedirect.com/science/article/pii/S0021915015301933
2016 - Full Study ~ Involvement of endocannabinoid neurotransmission in the bed nucleus of
stria terminalis in cardiovascular responses to acute restraint stress
in rats. (Brazil) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055136/
2016 - Full Study ~ The role of perivascular adipose tissue in obesity-induced vascular dysfunction. (Germany) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610151/
2016 - Full Study ~ The Effect of Chronic Activation of the Novel Endocannabinoid Receptor
GPR18 on Myocardial Function and Blood Pressure in Conscious Rats. (USA/
Egypt) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209303/
2016 - Full Study ~ Acute Toxicity Associated with Use of 5F-Derivations of Synthetic
Cannabinoid Receptor Agonists with Analytical Confirmation. (UK) (full –
2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135680/
2016 - Full Study ~ Clinical Effects of Synthetic Cannabinoid Receptor Agonists Compared
with Marijuana in Emergency Department Patients with Acute Drug
Overdose. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135672/
2016 - Full Study ~ Association Between Lifetime Marijuana Use and Cognitive Function in
Middle Age: The Coronary Artery Risk Development in Young Adults
(CARDIA) Study. (USA/ Switzerland) (full – 2016) http://archinte.jamanetwork.com/article.aspx?articleid=2484906
2016 - Full Study ~ Synthetic cannabinoid drug use as a cause or contributory cause of death (USA) (full–2016) https://www.academia.edu/25518565/Synthetic_cannabinoid_drug_use_as_a_cause_or_contributory_cause_of_death
2016 - Full Study ~ Synthetic Cannabinoid Abuse Resulting in ST-Segment Elevation Myocardial
Infarction Requiring Percutaneous Coronary Intervention. (USA) (click
“PDF Reader” for full – 2016) https://kundoc.com/pdf-synthetic-cannabinoid-abuse-resulting-in-st-segment-elevation-myocardial-infarct.html
2016 - Full Study ~ Effects of activation of endocannabinoid system on myocardial
metabolism. (Poland) (abst in English, link to PDF in Polish– 2016) https://phmd.pl/resources/html/article/details?id=142391
2016 - Full Study ~ The endogenous lipid N-arachidonoyl glycine is hypotensive and nitric
oxide-cGMP- dependent vasorelaxant. (Oman) (link to PDF – 2016) https://www.researchgate.net/publication/310816046_The_endogenous_lipid_N-
2016 - Full Study ~ arachidonoyl_glycine_is_hypotensive_and_nitric_oxide-cGMP-dependent_vasorelaxant
Circulating levels of endocannabinoids and oxylipins altered by dietary
lipids in older women are likely associated with previously identified
gene targets. (USA) (link to PDF – 2016) https://www.researchgate.net/publication/305630631_Circulating_levels_of_endocannabinoids_and_oxylipins_altered_by_dietary_lip
2016 - Full Study ~ ids_in_older_women_are_likely_associated_with_previously_identified_gene_targets
Signs and symptoms associated with synthetic cannabinoid toxicity:
systematic review. (New Zealand) (link to PDF – 2016) https://www.researchgate.net/publication/306526731_Signs_and_symptoms_associated_with_synthetic_cannabinoid_toxicity_System
2016 - Full Study ~ Pharmacological inhibition of FAAH activity in rodents: a
promising pharmacological approach for psychological – cardiac
comorbidity? (Italy/ Australia/ USA) (link to PDF – 2016) https://www.researchgate.net/publication/301734639_Pharmacological_inhibition_of_FAAH_activity_in_rodents_A_promising_pharmacological_approach_for_psychological-cardiac_comorbidity
2016 - Full Study ~ Overactivation of cannabinoid receptor type 1 in rostral ventrolateral
medulla promotes cardiovascular responses in spontaneously hypertensive
rats. (China) (link to PDF – 2016) https://www.researchgate.net/publication/310470715_Overactivation_of_cannabinoid_receptor_type_1_in_rostral_ventrolateral_medu
2016 - Full Study ~ lla_promotes_cardiovascular_responses_in_spontaneously_hypertensive_rats
Synthetic Cannabinoids and Their Effects on the Cardiovascular System.
(USA) (link to PDF – 2016) https://www.researchgate.net/publication/283422020_Synthetic_Cannabinoids_and_Their_Effects_on_the_Cardiovascular_System
2016 - Full Study ~ Potential Biomarkers for Depression Associated with Coronary Artery
Disease: A Critical Review. (Canada) (link to download – 2016) http://www.eurekaselect
.com/138787/article
2016 - Full Study ~ Can your heart handle the spice: A case of acute myocardial infarction and left ventricular apical thrombus. (USA) (click “researchgate” for download – 2016) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Can+your+heart+handle+the+spice%3A+A+case+of+acute+myocardial+infarction+and+left+ventricular+apical+thrombus.+++++++++++++++&btnG
2016 - Full Study ~ Marijuana Use and Short-Term Outcomes in Patients Hospitalized for Acute Myocardial. (USA) (interview–2016) https://medicalresearch.com/heart-disease/marijuana-use-short-term-outcomes-patients-hospitalized-acute-myocardial/22914/
2016 - Full Study ~ Cannabinoids and haemostasis. (Poland) (abst in English, link to full PDF in Polish–2016) https://www.researchgate.net/publication/305040888_Cannabinoids_and_haemostasis
2016 - Abstract Study ~ Abrupt Quitting of Long-term Heavy Recreational Cannabis Use is Not
Followed by Significant Changes in Blood Pressure and Heart Rate.
(Germany) (link to 1st page–2016) https://www.thieme-connect.com/DOI/DOI?10.1055/s-0035-1565242
2016 - Abstract Study ~ Age-specific influences of chronic administration of the fatty acid
amide hydrolase inhibitor URB597 on cardiovascular parameters and organ
hypertrophy in DOCA-salt hypertensive rats. (Poland) (abst – 2016) https://www.semanticscholar.org/paper/Age-specific-influences-of-chronic-administration-Toczek-Baranowska-
Kuczko/d3e2b54c36a417b6cec6463c7e32b9ece130e817
2016 - Abstract Study ~ Adverse effects after the use of JWH-210 – a case series from the EU Spice II plus project. (Germany) (abst – 2016) https://www.semanticscholar.org/paper/Adverse-effects-after-the-use-of-JWH-210-a-case-the-Hermanns-Clausen-Kithinji/7f72a2b975a3b9ff5c94c83c951d24cd69574361
2016 - Abstract Study ~ Protective role of cannabinoid CB1 receptors and vascular effects of
chronic administration of FAAH inhibitor URB597 in DOCA-salt
hypertensive rats. (Poland) (abst – 2016) http://www.sciencedirect.com/science/article/pii/S0024320516301643
2016 - Abstract Study ~ Repeated Thrombosis After Synthetic Cannabinoid Use. (USA) (abst – 2016) http://www.ncbi.nlm.nih.gov/pubmed/27595371
2016 - Abstract Study ~ Selective modulator of cannabinoid receptor type 2 reduces memory
impairment and infarct size during cerebral hypoperfusion and vascular
dementia. (India) (abst – 2016) http://www.ncbi.nlm.nih.gov/pubmed/27586843
2016 - Abstract Study ~ Acute Effects of Synthetic Cannabinoids: Update 2015. (France) (abst – 2016) https://www.semanticscholar.org/paper/Acute-effects-of-synthetic-cannabinoids%3A-Update-Tournebize-Gibaja/a2a9b8b350237715f8b58475580b4ffa05ea1adc
2016 - Abstract Study ~ Targeting brain and peripheral plasticity of the lipidome in acute
kainic acid-induced epileptic seizures in mice via quantitative mass
spectrometry. (Germany) (abst – 2016) http://www.sciencedirect.com/science/article/pii/S1388198116303092
2016 - Abstract Study ~ Plasma palmitoylethanolamide (PEA) as a potential biomarker for impaired
coronary function. (Italy/ Switzerland/ USA) (abst – 2016) https://www.ncbi.nlm.nih.gov/pubmed/27989579
2016 - Abstract Study ~ Δ9-Tetrahydrocannabinol concentrations in exhaled breath and
physiological effects following cannabis intake – a pilot study using
illicit cannabis. (Belgium/ Italy/ Sweden) (abst – 2016) http://www.sciencedirect.com/science/article/pii/S0009912016300996
2016 - Abstract Study ~ Synthetic Cannabinoids-Further Evidence Supporting the Relationship Between Cannabinoids and Psychosis. (Italy) (abst – 2016) http://www.ncbi.nlm.nih.gov/pubmed/26970364
2012 - Study ~ Cannabinoids and atherosclerotic coronary heart disease.
2012 - Study ~ Cannabinoid 1 (CB1) receptor mediates WIN55, 212-2 induced hypothermia and improved survival in a rat post-cardiac arrest model.
2012 - Study ~ Angiotensin
II induces vascular endocannabinoid release, which attenuates its
vasoconstrictor effect via CB1 cannabinoid receptors.
2012 - Study ~ Vascular
metabolism of anandamide to arachidonic acid affects myogenic
constriction in response to intraluminal pressure elevation.
2012 - Study ~ Subjective, cognitive and cardiovascular dose-effect profile of nabilone and dronabinol in marijuana smokers.
2012 - Study ~ Cannabinoid receptor CB2 protects against balloon-induced neointima formation.
2012 - Study ~ Targeting cannabinoid receptor CB(2 ) in cardiovascular disorders: promises and controversies.
2012 - Study ~ Vascular
metabolism of anandamide to arachidonic acid affects myogenic
constriction in response to intraluminal pressure elevation.
2011 - Study ~ The potential for clinical use of cannabinoids in treatment of cardiovascular diseases.
2011 - Study ~ Endocannabinoid system in cardiovascular disorders - new pharmacotherapeutic opportunities.
2011 - Study ~ Acute
administration of cannabidiol in vivo suppresses ischaemia-induced
cardiac arrhythmias and reduces infarct size when given at reperfusion.
2011 - Study ~ Cannabidiol as an anti-arrhythmic, the role of the CB1 receptors.
2011 - Study ~ Distinctive
effects of plant protein sources on renal disease progression and
associated cardiac hypertrophy in experimental kidney disease.
2011 - Study ~ Deficiency of type 1 cannabinoid receptors worsens acute heart failure induced by pressure overload in mice.
2011 - Study ~ G1359A polymorphism in the cannabinoid receptor-1 gene is associated with coronary artery disease in the Chinese Han population.
2011 - Study ~ The
effects of hempseed meal intake and linoleic acid on Drosophila models
of neurodegenerative diseases and hypercholesterolemia.
2011 - Study ~ Win
55,212-2 reduces cardiac ischaemia-reperfusion injury in zucker
diabetic fatty rats: role of cb2 receptors and cardiac inos/enos
expression.
2011 - Study ~ Cannabinoid-2 Receptor Activation Protects against Infarct and Ischemia/Reperfusion Heart Injury.
2011 - Study ~ Endocannabinoids and the cardiovascular response to stress.
2011 - Study ~ Cardiotoxicity associated with the synthetic cannabinoid, K9, with laboratory confirmation.
2011 - Study ~ Effects of intracisternal administration of cannabidiol on the cardiovascular and behavioral responses to acute restraint stress.
2011 - Study ~ The effect of dietary hempseed on atherogenesis and contractile function in aortae from hypercholesterolemic rabbits.
2011 - Study ~ Targeting the Endocannabinod System to Limit Myocardial and Cerebral Ischemic and Reperfusion Injury.
2011 - Study ~ Cannabidiol (CBD) as an Anti-Arrhythmic.
2010 - Study ~ Acute
administration of cannabidiol in vivo suppresses ischaemia-induced
cardiac arrhythmias and reduces infarct size when given at reperfusion.
2010 - Study ~ The cardiac and haemostatic effects of dietary hempseed.
2010 - Study ~ Endogenous cannabinoid signaling is essential for stress adaptation.
2010 - Study ~ Pharmacologically induced hypothermia with cannabinoid receptor agonist WIN55, 212-2 after cardiopulmonary resuscitation.
2010 - Study ~ Acute
administration of cannabidiol in vivo suppresses ischaemia-induced
cardiac arrhythmias and reduces infarct size when given at reperfusion.
2010 - Study ~ Substantially
altered expression pattern of cannabinoid receptor 2 and activated
endocannabinoid system in patients with severe heart failure.
2010 - Study ~ Interaction between anandamide and sphingosine-1-phosphate in mediating vasorelaxation in rat coronary artery.
2010 - Patent ~ US Patent Application 20100158973 - THERAPEUTIC USES OF CANNABIDIOL COMPOUNDS.
2009 - Study - Cannabinoids and atherosclerosis.
2009 - Study ~ Endocannabinoids and cardiac contractile function: pathophysiological implications.
2009 - Study ~ Endocannabinoids and cannabinoid analogues block cardiac hKv1.5 channels in a cannabinoid receptor-independent manner.
2009 - Study ~ Endocannabinoids and the Heart.
2009 - Study ~ The emerging role of the endocannabinoid system in cardiovascular disease.
2009 - Study ~ Endocannabinoid signalling as an anti-inflammatory therapeutic target in atherosclerosis: does it work?
2009 - Study ~ CB1 and CB2 cannabinoid receptors differentially regulate the production of reactive oxygen species by macrophages.
2009 - Study ~ Time-dependent vascular actions of cannabidiol in the rat aorta.
2009 - Study ~ Endocannabinoids and cardiovascular prevention: real progress?
2008 - Study - Function of cannabinoids in heart failure.
2008 - Study ~ The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin.
2008 - Study ~ Cannabinoid receptors in acute and chronic complications of atherosclerosis.
2008 - Study ~ Endocannabinoids and Liver Disease. V. Endocannabinoids as mediators of vascular and cardiac abnormalities in cirrhosis.
2008 - Study ~ CB1 Cannabinoid Receptor Inhibition: Promising Approach for Heart Failure?
2008 - Study ~ 'Entourage'
effects of N-palmitoylethanolamide and N-oleoylethanolamide on
vasorelaxation to anandamide occur through TRPV1 receptors.
2008 - Study ~ Modulation of the Endocannabinoid System in Cardiovascular Disease.
2008 - Study ~ Acute hypertension reveals depressor and vasodilator effects of cannabinoids in conscious rats.
2008 - Study ~ Endocannabinoids and cannabinoid receptors in ischaemia–reperfusion injury and preconditioning.
2008 - Study ~ Virodhamine relaxes the human pulmonary artery through the endothelial cannabinoid receptor and indirectly through a COX product.
2008 - Study ~ Endocannabinoids, blood pressure and the human heart.
2008 - Study ~ Function of cannabinoids in heart failure.
2008 - Study ~ The endocannabinoid system: an osteopathic perspective.
2008 - Study ~ Dexanabinol prevents development of vasospasm in the rat femoral artery model.
2007 - Study - Cannabinoids and cardiovascular disease.
2007 - Study - Cannabinoids as therapeutic agents in cardiovascular disease.
2007 - Study - The in vitro and in vivo cardiovascular effects of {Delta}9-tetrahydrocannabinol.
2007 - Study - Cannabidiol protects against myocardial ischemic reperfusion injury.
2007 - Study - Cannabinoids as therapeutic agents in cardiovascular disease: a tale of passions and illusions.
2007 - Study ~ Characterization of the vasorelaxant mechanisms of the endocannabinoid anandamide in rat aorta.
2007 - Study ~ The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects.
2007 - Study ~ Endocannabinoids acting at CB1 receptors mediate the cardiac contractile dysfunction in vivo in cirrhotic rats.
2007 - Study ~ Endocannabinoids and the haematological system.
2007 - Study ~ Cannabinoids and cardiovascular disease: a tale of passions and illusions.
2007 - Study ~ GPR55 and the vascular receptors for cannabinoids.
2007 - Study ~ Cannabidiol , a nonpsychoactive Cannabis constituent, protects against myocardial ischemic reperfusion injury.
2007 - Study ~ Cardiovascular effects of cannabinoids in conscious spontaneously hypertensive rats.
2007 - Study ~ Effect of dietary hempseed intake on cardiac ischemia-reperfusion injury.
2007 - Study ~ Cannabinoids and cardiovascular disease: the outlook for clinical treatments.2006 - Study ~ Illicit Drug Use in Young Adults and Subsequent Decline in General Health: The Coronary Artery Risk Development in Young Adults (CARDIA) Study.
2006 - Study ~ Signaling pathways involved in the cardioprotective effects of cannabinoids.
2006 - Study - The endogenous cardiac cannabinoid system: a new protective mechanism.
2006 - Study - Delta-9-tetrahydrocannabinol protects cardiac cells from hypoxia via CB2 receptor activation and nitric oxide production.
2006 - Study - Does Cannabis Hold the Key to Treating Cardiometabolic Disease?
2006 - Study - Marijuana use, diet, body mass index, and cardiovascular risk factors.
2005 - Study - Cardiovascular pharmacology of cannabinoids.
2005 - Study ~ Anandamide reduces infarct size in rat isolated hearts subjected to ischaemia–reperfusion by a novel cannabinoid mechanism.
2005 - Study ~ Effects
of AM281, a cannabinoid antagonist, on systemic haemodynamics, internal
carotid artery blood flow and mortality in septic shock in rats.
2005 - Study ~ The cardiovascular actions of anandamide: more targets?
2005 - Study ~ Increased anandamide induced relaxation in mesenteric arteries of cirrhotic rats: role of cannabinoid and vanilloid receptors.
2005 - Study ~ Cardiac and vascular effects of cannabinoids: toward a therapeutic use?
2005 - Study ~ Influence of Anandamide, the Endogenous Agonist of Cannabinoid Receptors on the Circulatory System.
2004 - Study ~ Endocannabinoids Acting at Cannabinoid-1 Receptors Regulate Cardiovascular Function in Hypertension.
2004 - Study ~ Vasorelaxant activities of the putative endocannabinoid virodhamine in rat isolated small mesenteric artery.
2003 - Study ~ Endocannabinoids protect the rat isolated heart against ischaemia.
2003 - Study ~ Vasodilator actions of abnormal-cannabidiol in rat isolated small mesenteric artery.
2003 - Study ~ Cannabinoid
CB2 receptor activation reduces mouse myocardial ischemia-reperfusion
injury: involvement of cytokine/chemokines and PMN.
2003 - Study ~ A new endothelial target for cannabinoids.
2003 - Study ~ Endocannabinoids as mediators in the heart: a potential target for therapy of remodelling after myocardial infarction?
2002 - Study ~ Influence
of the CB1 receptor antagonist, AM 251, on the regional haemodynamic
effects of WIN-55212-2 or HU 210 in conscious rats.
2002 - Study ~ Endocannabinoids are implicated in the infarct size-reducing effect conferred by heat stress preconditioning in isolated rat hearts.
2002 - Study ~ Estrogen stimulates arachidonoylethanolamide release from human endothelial cells and platelet activation.
2002 - Study ~ Activation of cannabinoid receptors decreases the area of ischemic myocardial necrosis.
2002 - Study ~ Anandamide
and R-(+)-methanandamide prevent development of ischemic and
reperfusion arrhythmia in rats by stimulation of CB2-receptors.
2002 - Study ~ Increase
of the heart arrhythmogenic resistance and decrease of the myocardial
necrosis zone during activation of cannabinoid receptors.
2002 - Study ~ Endogenous cannabinoids improve myocardial resistance to arrhythmogenic effects of coronary occlusion and reperfusion: a possible mechanism.
2001 - Study ~ Endogenous cannabinoids mediate hypotension after experimental myocardial infarction.
2001 - Study ~ Mechanisms of anandamide-induced vasorelaxation in rat isolated coronary arteries.
2001 - Study ~ Endocannabinoids are implicated in the infarct size-reducing effect conferred by heat stress preconditioning in isolated rat hearts.
2001 - Study ~ Endogenous cannabinoid anandamide increases heart resistance to arrhythmogenic effects of epinephrine: role of CB(1) and CB(2) receptors.2000 - Study ~ Cardiovascular effects of endocannabinoids--the plot thickens.
2000 - Study ~ Involvement of central and peripheral cannabinoid receptors in the regulation of heart resistance to arrhythmogenic effects of epinephrine.
2000 - Study ~ Cardiovascular effects of endocannabinoids--the plot thickens.
2000 - Study ~ Involvement
of central and peripheral cannabinoid receptors in the regulation of
heart resistance to arrhythmogenic effects of epinephrine.
1997 - Study ~ Cannabinoid-Induced Hypotension and Bradycardia in Rats Is Mediated by CB1-Like Cannabinoid Receptors.
1995 - Study ~ Development of HU-211 as a neuroprotectant for ischemic brain damage.
1995 - Study ~ Novel antagonist implicates the CB1 cannabinoid receptor in the hypotensive action of anandamide.
1992 - Study - Changes in middle cerebral artery velocity after marijuana.
1989 - Study ~ The inhibitory effects of cannabinoids, the active constituents of Cannabis sativa L. on human and rabbit platelet aggregation.
1986 - Study ~ Effects of acute marijuana smoking in post-menopausal women.
1981 - Study ~ The cardiovascular and autonomic effects of repeated administration of delta-9-tetrahydrocannabinol to rhesus monkeys.
1980 - Study ~ Cannabinoids. II. Cardiovascular Effects.
1977 - Study ~ Propranolol Effects on Acute Marihuana Intoxication in Man.
1977 - Study ~ Short-term effects of smoked marihuana on left ventricular function in man.
1976 - Study ~ The Effects of Delta-9-Tetrahydrocannabinol (Cannabis) on Cardiac Performance with and without Beta Blockade.
1975 - Study ~ Intravenous delta9-Tetrahydrocannabinol: Effects of ventilatory control and cardiovascular dynamics.
1973 - Letter ~ Effects of cannabis roots on the heart
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