Cannabis Research A-Z

Many studies have been released which found that cannabis can be an effective treatment for depression.

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2018 - Full ~ The selective reversible FAAH inhibitor, SSR411298, restores the development of maladaptive behaviors to acute and chronic stress in rodents.

Scientific Reports Journal.

2018 - Full ~ Cannabis Essential Oil: A Preliminary Study for the Evaluation of the Brain Effects.

Hindawi: Evidence-Based Complementary and Alternative Medicine.

2018 - Full ~ Detection of Significant Association Between Variants in Cannabinoid Receptor 1 Gene (CNR1) and Personality in African-American Population.

Frontiers In Genetics.

2018 - Full ~ Negative urgency partially accounts for the relationship between major depressive disorder and marijuana problems.

Borderline Personality Disorder and Emotional Dysregulation.

2018 - Full ~ Prolonged Cannabidiol Treatment Effects on Hippocampal Subfield Volumes in Current Cannabis Users.

Cannabis and Cannabinoid Research.

2018 - Abstract ~ CB1 cannabinoid receptor ligands augment the antidepressant-like activity of biometals (magnesium and zinc) in the behavioural tests.

Journal of Pharmacy and Pharmacology.

2018 - Abstract ~ Prospects of Cannabidiol for Easing Status Epilepticus-Induced Epileptogenesis and Related Comorbidities.

Molecular Neurobiology.

2018 - Abstract ~ Evaluation of different drug classes on transient sciatic nerve injury-depressed marble burying in mice.

Pain Journal.

2018 - Abstract ~ Impacts of cannabinoid receptor ligands on nicotine- and chronic mild stress-induced cognitive and depression-like effects in mice.

2018 - Abstract ~ The association between lifetime cannabis use and dysthymia (persistent mild depression) across six birth decades.

2018 - Abstract ~ Circulating endocannabinoids and affect regulation in human subjects.

Journal of Psychoneuroendocrinology.

2018 - Abstract ~ Substance Use and Suicide in Pacific Islander, American Indian, and Multiracial Youth. 

American Journal of Preventative Medicine.

2018 - Abstract ~ The role of depressive symptoms in treatment of adolescent cannabis use disorder with N-Acetylcysteine.

2018 - Abstract ~ Cannabidiol Induces Rapid and Sustained Antidepressant-Like Effects Through Increased BDNF Signaling and Synaptogenesis in the Prefrontal Cortex.

Molecular Neurobiology.

2018 - Abstract ~ Association of Cannabis With Long-Term Clinical Symptoms in Anxiety and Mood Disorders: A Systematic Review of Prospective Studies.

Journal of Clinical Psychiatry.

2018 - Abstract ~ Sub-chronic treatment with cannabidiol but not with URB597 induced a mild antidepressant-like effect in diabetic rats.

2018 - Abstract ~ Antidepressant-like effect induced by Cannabidiol is dependent on brain serotonin levels.

2018 - Abstract ~ Inhibition of Fatty Acid Amide Hydrolase Improves Depressive-Like Behaviors Independent of Its Peripheral Antinociceptive Effects in a Rat Model of NeuropathicPain.

OVID: Anesthesia & Analgesia.

2018 - Abstract ~ Itch and psyche: psychiatric aspects of pruritus.

International Journal of Dermatology.

2018 - Abstract ~ Relationships between substance abuse/dependence and psychiatric disorders based on polygenic scores.

International Behavioural and Neural Genetics Society: Genes, Brains, and Behavior.

2018 - Abstract ~ Effects of rTMS on Hippocampal Endocannabinoids and Depressive-like Behaviors in Adolescent Rats.

Neurochemical Research.

2018 - Abstract ~ Integrating endocannabinoid signaling in the regulation of anxiety and depression.

APS: Acta Pharmacologica Sinica.

2018 - Abstract ~ Orbitofrontal connectivity is associated with depression and anxiety in marijuana-using adolescents.

2018 - Abstract ~ Risks and Benefits of Marijuana Use: A National Survey of U.S. Adults.

Annals of Internal Medicine.

2018 - Abstract ~ The endocannabinoid system in mental disorders: Evidence from human brain studies.

JAMA Otolaryngology: Head and Neck Surgery.

2014 - Study ~ Monoacylglycerol Lipase Inhibition Blocks Chronic Stress-Induced Depressive-Like Behaviors via Activation of mTOR Signaling

2014 - Study ~ Anti-depressive mechanism of repetitive transcranial magnetic stimulation in rat: The role of the endocannabinoid system.

2013 - Study ~ Effect of dietary fat type on anxiety-like and depression-like behavior in mice

2013 - Study ~ Translational evidence for the involvement of the endocannabinoid system in stress-related psychiatric illnesses

2013 - Study ~ Screening genetic variability at the CNR1 gene in both major depression etiology and clinical response to citalopram treatment.

2013 - Study ~ Additive effect of rimonabant and citalopram on extracellular serotonin levels monitored with in vivo microdialysis in rat brain.

2013 - Study ~ Entopeduncular nucleus endocannabinoid system modulates sleep-waking cycle and mood in rats.

2013 - Study ~ Can Marijuana Reduce Social Pain?

2013 - Study ~ Sleep Quality Moderates the Relation between Depression Symptoms and Problematic Cannabis Use among Medical Cannabis Users

2013 - Study ~ The effects of anandamide signaling enhanced by the FAAH inhibitor URB597 on coping styles in rats.

2013 - Study ~ Cannabinoids, Neurogenesis and Antidepressant Drugs: Is there a Link?

2013 - Study ~ The endocannabinoid system and emotional processing: A pharmacological fMRI study with ∆9-tetrahydrocannabino

2013 - Study ~ Cannabinoid Receptor Activation Prevents the Effects of Chronic Mild Stress on
Emotional Learning and LTP in a Rat Model of Depression.

2013 - Study ~ Endocannabinoid Signaling in the Etiology and Treatment of Major Depressive Illness.

2013 - Study ~ The endocannabinoid system and its possible role in neurobiology of psychiatric
disorders

2013 - Study ~ Low frequency stimulation evokes serotonin release in the nucleus accumbens and induces long-term depression via production of endocannabinoid.

2013 - Study ~ Testing bidirectional effects between cannabis use and depressive symptoms: moderation by the serotonin transporter gene

2012 - Study ~ High on Life? Medical Marijuana Laws and Suicide.

2012 - Study ~ Serum contents of endocannabinoids are correlated with blood pressure in depressed women.

2012 - Study ~ Cannabinoid Receptor Genotype Moderation of the Effects of Childhood Physical Abuse on Anhedonia and Depression.

2012 - Study ~ Effect of delta-9-tetrahydrocannabinol on behavioral despair and on presynaptic and postsynaptic serotonergic transmission.

2012 - Study ~ Nature Against Depression.

2012 - Study ~ Lower levels of cannabinoid 1 receptor mRNA in female eating disorder patients: Association with wrist cutting as impulsive self-injurious behavior.

2012 - Study ~ Expression pattern of the cannabinoid receptor genes in the frontal cortex of mood disorder patients and mice selectively bred for high and low fear.

2012 - Study ~ The combined effects of parental divorce and parental history of depression on cannabis use in young adults in France.

2012 - Study ~ Genetic variability in the endocannabinoid system and 12-week clinical response to citalopram treatment: the role of the CNR1, CNR2 and FAAH genes

2012 - Study ~ Opposing local effects of endocannabinoids on the activity of noradrenergic neurons and release of noradrenaline: relevance for their role in depression and in the actions of CB(1) receptor antagonists.

2012 - Study ~ Essential fatty acids and lipid mediators. Endocannabinoids

2012 - Study ~ Endocannabinoid system and mood disorders: Priming a target for new therapies.

2011 - Study ~ Gadolinium-HU-308-incorporated micelles.

2011 - Study ~ Nutritional omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions.

2011 - Study ~ Endocannabinoid system dysfunction in mood and related disorders.

2011 - Study ~ Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress.

2011 - Study ~ Cannabinoids and emotionality: a neuroanatomical perspective.

2011 - Study ~ Testing bidirectional effects between cannabis use and depressive symptoms: moderation by the serotonin transporter gene.

2010 - Study ~ Antidepressant-like effect of delta9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L.

2010 - Study ~ Brain CB2 Receptors: Implications for Neuropsychiatric Disorders.

2010 - Study ~ Uni-Morbid and Co-Occurring Marijuana and Tobacco Use: Examination of Concurrent Associations with Negative Mood States.

2010 - Study ~ Genes differentially expressed in CB1 knockout mice: involvement in the depressive-like phenotype.

2010 - Study ~ Deficiency in Endocannabinoid Signaling in the Nucleus Accumbens Induced by Chronic Unpredictable Stress.

2009 - Study ~ Circulating endocannabinoids and N-acyl ethanolamines are differentially regulated in major depression and following exposure to social stress.

2009 - Study ~ Impairments in Endocannabinoid Signaling and Depressive Illness.

2009 - Study ~ Protracted cannabinoid administration elicits antidepressant behavioral responses in rats: role of gender and noradrenergic transmission.

2009 - Study ~ Cannabis and suicide: longitudinal study.

2008 - Study ~ Treating depression with cannabinoids.

2008 - Study ~ Nicotine (NC)-induced "depressive" behavioral symptoms and effects of antidepressants including cannabinoids (CBs).

2008 - Study ~ Animal research highlights a therapeutic potential of cannabinoids for the treatment of depression.

2007 - Study ~ Chronologically overlapping occurrences of nicotine-induced anxiety- and depression-related behavioral symptoms: effects of anxiolytic and cannabinoid drugs.

2007 - Study ~ Cannabinoids elicit antidepressant-like behavior and activate serotonergic neurons through the medial prefrontal cortex.

2007 - Study ~ Antidepressant-like activity of the fatty acid amide hydrolase inhibitor URB597 in a rat model of chronic mild stress.

2007 - Study ~ Dronabinol and marijuana in HIV-positive marijuana smokers: caloric intake, mood, and sleep.

2006 - Study ~ Decreased depression in marijuana users.

2006 - Study ~ The synthetic cannabinoid nabilone improves pain and symptom management in cancer patients.

2006 - Study ~ Marijuana use and depression among adults: Testing for causal associations.

2006 - Study ~ Do patients use marijuana as an antidepressant?

2006 - Study ~ A possible role for the endocannabinoid system in the neurobiology of depression.

2005 - Study ~ Cannabinoids promote hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects.

2005 - Study ~ Antidepressant-like activity by blockade of anandamide hydrolysis.

2005 - Study ~ Depression in Parkinson's disease is related to a genetic polymorphism of the cannabinoid receptor gene (CNR1).

2005 - Study ~ Antidepressant-like Activity and Modulation of Brain Monoaminergic Transmission by Blockade of Anandamide Hydrolysis.

2005 - Study ~ Decreased Depression in Marijuana Users.

2004 - Study ~ Association between cannabis use and depression may not be causal, study says.

2001 - Study ~ Therapeutic Aspects of Cannabis and Cannabinoids.

2000 - Study ~ Anxiety with Depression Research Review.