Open Access

CANNABICHROMENE/ CBC & Cannabis studies completed


Cannabichromene (CBC) is a cannabinoid found in the Cannabis plant. It bears structural similarity to the other natural cannabinoids, including tetrahydrocannabinol, tetrahydrocannabivarin, cannabidiol, and cannabinol, among others.

Evidence has suggested that it may play a role in the
anti-inflammatory and anti-viral effects of cannabis, and may contribute to the overall analgesic effects of medical cannabis. A study done in March 2010 showed that CBC along with cannabidiol and tetrahydrocannabinol have antidepressant effects. Another study showed that CBC helps promote neurogenesis.
molecular structure of CBC

Science and Research

Undated - News ~ Phytocannabinoids

2012 - Study ~ Inhibitory effect of cannabichromene, a major non-psychotropic cannabinoid extracted from Cannabis sativa, on inflammation-induced hypermotility in mice.

2011 - Study ~ The endocannabinoid system and cancer: therapeutic implication

2011 - Patent ~ Phytocannabinoids for use in the treatment of cancer - Patent GB2478595 (A) ― 2011-09-14

2011 - Study ~ Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP

channels and endocannabinoid metabolic enzymes.

2011 - Study ~ The intersection between cannabis and cancer in the United States.

2011 - Study ~ Non-psychoactive cannabinoids modulate the descending pathway of antinociception in anaesthetized rats through several mechanisms of action

2011 - Study ~ Cannabinoids in children

2011 - News ~ Cannabis Science Reports: National Cancer Institute Updates Confirm Successful Cancer Treatments with Medical Cannabis.

2010 - Study ~ Antidepressant-like effect of Delta(9)-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L.

2010 - Study ~ Disposition of Cannabichromene, Cannabidiol, and Δ9-Tetrahydrocannabinol and its Metabolites in Mouse Brain following Marijuana Inhalation Determined by High-Performance Liquid Chromatography-Tandem Mass Spectrometry

2010 - Study ~ Pharmacological evaluation of the natural constituent of Cannabis sativa, cannabichromene and its modulation by Δ9-tetrahydrocannabinol

2009 - Study ~ Evaluation of Prevalent Phytocannabinoids in the Acetic Acid Model of Visceral Nociception

2009 - Study ~ TRB3 links ER stress to autophagy in cannabinoid anti-tumoral action.

2008 - Study ~ Antibacterial cannabinoids from Cannabis sativa: a structure-activity study.

1990 - Study ~ In vitro metabolism of cannabichromene in seven common laboratory animals.

1989 - Patent ~ Antiinflammatory and antimicrobial compounds and compositions
United States Patent 4837228

1984 - Study ~ Intraocular pressure, ocular toxicity and neurotoxicity after administration of delta 9-tetrahydrocannabinol or cannabichromene.

1983 - Study ~ Neurobehavioral actions of cannabichromene and interactions with delta 9-tetrahydrocannabinol.

1983 - Study ~ Allergenic properties of naturally occurring cannabinoids.

1982 - Study ~ Process for preparing cannabichromene

1981 - Study ~ Biological activity of cannabichromene, its homologs and isomers.

1975 - Study ~ Constituents of Cannabis sativa L. VIII: Possible biological application of a new method to separate cannabidiol and cannabichromene.

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