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CANCER - PROSTATE & Cannabis studies completed 

Overview

Prostate cancer is a global public health problem, and it is the most common cancer in American men and the second cause for cancer-related death. Experimental evidence shows that prostate tissue possesses cannabinoid receptors and their stimulation results in anti-androgenic effects.


Prostate cancer starts in the cells of the prostate. The prostate is part of a man's reproductive system. Its main function is to make part of the liquid (seminal fluid) that mixes with sperm from the testicles to make semen. Semen is ejaculated during sex. The prostate is a walnut-sized gland just below the bladder and in front of the rectum. It surrounds part of the urethra, the tube that carries urine and semen through the penis.


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Science & Research

2014 - Study ~ Ketoconazole Inhibits the Cellular Uptake of Anandamide via Inhibition of FAAH at Pharmacologically Relevant Concentrations

2014 - Study ~ Honokiol inhibits androgen receptor activity in prostate cancer cells

2013 - Study ~ Non-THC cannabinoids inhibit prostate carcinoma growth in vitro and in vivo: pro-
apoptotic effects and underlying mechanisms.

2013 - Study ~ The Endocannabinoid System and Sex Steroid Hormone-Dependent Cancers

2013 - Study ~ Synthetic cannabinoid quinones: Preparation, in vitro antiproliferative effects and in vivo prostate antitumor activity.

2013 - Patent ~ US Patent Application 20130059018 - PHYTOCANNABINOIDS IN THE
TREATMENT OF CANCER

2013 - News ~ Tommy Chong Is "Cancer Free;" Claims Marijuana Cures Cancer

2012 - Study ~ The role of cannabinoids in prostate cancer: Basic science perspective and potential clinical applications.

2012 - Study ~ Non-THC cannabinoids counteract prostate carcinoma growth in vitro and in vivo: pro-apoptotic effects and underlying mechanisms.

2012 - News ~ Tommy Chong Fighting Prostate Cancer With Cannabis Oil.

2011 - Study ~ The endocannabinoid system and cancer: therapeutic implication.

2011 - Study ~ Phytocannabinoids for use in the treatment of cancer - Patent GB2478595 (A) ― 2011-09-14.

2011 - Study ~ The endocannabinoid system in prostate cancer.

2011 - Study ~ Omega-3 N-acylethanolamines are endogenously synthesised from omega-3 fatty acids in different human prostate and breast cancer cell lines.

2011 - Study ~ Cannabinoid Receptor Type 1 (CB1) Activation Inhibits Small GTPase RhoA Activity and Regulates Motility of Prostate Carcinoma Cells.

2011 - Study ~ Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent.

2011 - Study ~ The putative cannabinoid receptor GPR55 defines a novel autocrine loop in cancer cell proliferation.

2010 - Study ~ Cannabinoid receptor-dependent and -independent anti-proliferative effects of omega-3 ethanolamides in androgen receptor-positive and -negative prostate cancer cell lines.

2009 - Study - Inhibition of human tumour prostate PC-3 cell growth by cannabinoids R(+)-Methanandamide and JWH-015: Involvement of CB2 - Abstract.

2009 - Study - Chemicals found in cannabis may help fight prostate cancer.

2009 - Study ~ The cannabinoid R+ methanandamide induces IL-6 secretion by prostate cancer PC3 cells.

2009 - News ~ Active Chemicals in Cannabis Inhibits Prostate Cancer Cell Growth.

2009 - News ~ Cannabis is linked to a 'cancer cure'.

2009 - News ~ Cannabis chemicals may help fight prostate cancer.

2009 - News ~ Chemicals in cannabis found to stop prostate cancer.

2009 - News ~ Active cannabis chemicals halt prostate cancer cell growth.

2009 - News ~ Cannabis may apparently stop prostate cancer growth.

2009 - News ~ Medical Marijuana and Cancer, Prostate.

2008 - Study ~ Endocannabinoids in endocrine and related tumours.

2007 - Study ~ Diverse roles of 2-arachidonoylglycerol in invasion of prostate carcinoma cells: Location, hydrolysis and 12-lipoxygenase metabolism.

2007 - Study ~ US Patent Application 20070041994 - Compositions and methods for treating prostate disorders.

2007 - Study ~ Cannabinoid receptors agonist WIN-55,212-2 inhibits angiogenesis, metastasis and tumor growth of androgen-sensitive prostate cancer cell CWR22R{nu}1 xenograft in athymic nude mice.

2006 - Study ~ Cannabinoid Receptor Agonist-induced Apoptosis of Human Prostate Cancer Cells LNCaP Proceeds through Sustained Activation of ERK1/2 Leading to G1 Cell Cycle Arrest.

2005 - Study - Cannabinoid Receptor as a Novel Target for the Treatment of Prostate Cancer.

2005 - Study ~ A new class of inhibitors of 2-arachidonoylglycerol hydrolysis and invasion of prostate cancer cells.

2005 - Study ~ A new class of inhibitors of 2-arachidonoylglycerol hydrolysis and invasion of prostate cancer cells.

2004 - Study ~ 2-Arachidonoylglycerol A Novel Inhibitor of Androgen-Independent Prostate Cancer Cell Invasion.

2003 - Study - Anti-proliferative and apoptotic effects of anandamide in human prostatic cancer cell lines: implication of epidermal growth factor receptor down-regulation and ceramide production.

2003 - Study ~ Expression of functionally active cannabinoid receptor CB1 in the human prostate gland.

2000 - Study - Suppression of Nerve Growth Factor Trk Receptors and Prolactin Receptors by Endocannabinoids Leads to Inhibition of Human Breast and Prostate Cancer Cell Proliferation.

1999 - Study - Δ9-Tetrahydrocannabinol induces apoptosis in human prostate PC-3 cells via a receptor-independent mechanism.


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