CANCER - MELANOMA & Cannabis studies
Overview
Melanoma is a type of skin cancer which forms from melanocytes (pigment containingcells in the skin). In women, the most common site is the legs, and in men, it's the back.
Whereas surgery and chemotherapy work only by killing the cancer cells, hemp oil treatment for melanoma works on three fronts. The CBD in the hemp oil: Allegedly Kills the melanoma cancerous cells. Manages pain and inflammations that accompany the cancer. Hemp Oil boosts the bodies endocannabinoid system, which enables the body to fight the cancer on its own.
Antioxidants, such as retinol, are important for a healthy immune system. Studies have found that higher intake of retinol-rich foods, such as fish, milk, eggs, dark green leafy vegetables, and orange/yellow fruits and vegetables led to a 20 percent reduced risk of developing melanoma.
Science & Research
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How to treat skin cancer with cannabis oil
How to treat skin cancer with cannabis oil
2013 - Study ~ Cannabinoid receptor 2 is upregulated in melanoma.
2013 - Study ~ Anticancer activity of anandamide in human cutaneous melanoma cells.
2013 - Study ~ Calcium regulation by temperature-sensitive transient receptor potential channels in human uveal melanoma cells.
2012 - Study ~ Revisiting CB1 Receptor as Drug Target in Human Melanoma.
2012 - Study ~ The Expression and Significance of Cannabinoid Receptor 2 in Non-infectious Granuloma and Malignant Melanoma
2011 - Study ~ Inhibition of basal and ultraviolet B-induced melanogenesis by cannabinoid CB(1) receptors: a keratinocyte-dependent effect.
2011 - Study ~ The
antimitogenic effect of the cannabinoid receptor agonist WIN55212-2 on
human melanoma cells is mediated by the membrane lipid raft.
2011 - Study ~ Inhibition of basal and ultraviolet B-induced melanogenesis by cannabinoid CB(1) receptors: a keratinocyte-dependent effect.
2009 - Study ~ Cannabinoid receptor-1 modulation induces apoptosis of human melanoma cells
2006 - Study - Dronabinol for supportive therapy in patients with malignant melanoma and liver metastases
1997 - Study - Intractable nausea and vomiting due to gastrointestinal mucosal metastases relieved by tetrahydrocannabinol
Intractable nausea and vomiting due to gastrointestinal mucosal metastases
Dronabinol for supportive therapy in patients with malignant melanoma and liver metastases
| Title | [Dronabinol for supportive therapy in patients with malignant melanoma and liver metastases.] [Article in German] | |
|---|---|---|
| Author(s) | Zutt M, Hanssle H, Emmert S, Neumann C, Kretschmer L. | |
| Journal, Volume, Issue | Hautarzt 2006;57(5):423-7. | |
| Major outcome(s) | A significant increase in appetite and decrease in nausea in most patients. | |
| Indication | Nausea/vomiting;Appetite loss/weight loss;Cancer;Cancer chemotherapy | Abstract |
| Medication | Delta-9-THC | BACKGROUND: Loss of appetite and nausea can reduce the quality of life of patients with malignant melanoma and liver metastases. Often established antiemetic drugs fail to bring relief. Tetrahydrocannabinol (THC, Marinol (TM)), which is the active agent of Indian hemp, has been used successfully in this situation for other malignant tumors.PATIENTS AND METHODS: We treated 7 patients with hematogenous metastatic melanoma and liver metastases suffering from extensive loss of appetite and nausea supportively with dronabinol (Marinol((R))). All of these patients had previously received standard antiemetic therapy without adequate relief. Dronabinol is a synthetic Delta-tetrahydrocannabinol. The drug was administered in capsule form. We evaluated the palliative effects of dronabinol with a special patient evaluation form, which was filled out at the beginning of the therapy and again after 4 weeks.RESULTS: The majority of patients described a significant increase in appetite and decrease in nausea. These effects remained for some weeks, but then decreased as metastases progressed and the general condition worsened. All of the patients experienced slight to moderate dizziness, but it was not sufficiently troubling to cause interruption or termination of therapy.CONCLUSION: Loss of appetite and nausea due to liver metastases of malignant melanoma can be treated in individual cases supportively with Dronabinol. All Conditions Benefited by Cannabis
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| Route(s) | Oral | |
| Dose(s) | variable | |
| Duration (days) | ||
| Participants | 7 patients with hematogenous metastatic melanoma | |
| Design | Open study | |
| Type of publication | Medical journal | |
| Address of author(s) | Hautklinik und Poliklinik der Georg-August-Universitat Gottingen, Germany | |
| Full text |  | |
