Cancer / Leukemia & Cannabis

Overview

Leukemia is a cancer that starts in blood stem cells (immature blood cells) in the bone marrow. Bone marrow is the soft, spongy material that fills the center of most bones. Blood cells are made in the bone marrow. Blood stem cells develop into either myeloid stem cells or lymphoid stem cells.

In the year 2000, approximately 256,000 children and adults around the world developed some form of leukemia, and 209,000 died from it. About 90% of all leukemia new cases are diagnosed in adults.

Science & Research Studies

Journal: Cancers.
Journal: Children.

Journal: Expert Opinion on Investigational Drugs.

Department of Biological Sciences, University of Toronto.

Biomed Research International.

International Journal of Oncology.

Nature Journal.
Frontiers in Pharmacology.
Current Pharmaceutical Design.

Current Medicinal Chemistry: National Library of Medicine. (National Center of Biotechnology Information)

Plos One Journal.

BMC Cancer Journal.

Cellular and Molecular Life Sciences.


Biology of Blood and Marrow Transplantation.

Mulecules Journal.
Toxicology and Applied Pharmacology.
American Journal of Drug and Alcohol Abuse.

2008 - Abstract ~ Enhancing the in vitro cytotoxic activity of Delta9-tetrahydrocannabinol in leukemic cells through a combinatorial approach.

Journal of Leukemia and Lymphoma.


2008 - Full Study ~ Medical Marijuana Cannabis Use and Research.

Leukemia & Lymphoma Society.


2007 - Full Study ~ HU-331, a novel cannabinoid-based anticancer topoisomerase II inhibitor.

Molecular Cancer Theropeutics.


2006 - Abstract ~ Cannabidiol-Induced Apoptosis in Human Leukemia Cells: A Novel Role of Cannabidiol in the Regulation of p22phox and Nox4 Expression.

Molecular Pharmacology.


2006 - Abstract ~ Delta9-tetrahydrocannabinol-induced apoptosis in Jurkat leukemia T cells is regulated by translocation of Bad to mitochondria.

National Library of Medicine.


2006 - Full Study ~ Is there a temperature-dependent uptake of anandamide into cells?

British Journal Of Pharmacology.


2006 - Abstract ~ Parental marijuana use and risk of childhood acute myeloid leukaemia: a report from the Children's Cancer Group (United States and Canada)

Nationa;l Library of Medicine.


2006 - Abstract ~ The effects of cannabinoids on P-glycoprotein transport and expression in multidrug resistant cells.

Biochemical Pharmacology.


2005 - Abstract ~ Cannabis-induced cytotoxicity in leukemic cell lines: the role of the cannabinoid receptors and the MAPK pathway.

National Center of Biotechnology Information.


2003 - Abstract ~ Gamma-irradiation enhances apoptosis induced by cannabidiol, a non-psychotropic cannabinoid, in cultured HL-60 myeloblastic leukemia cells.
National Center of Biotechnology Information.
Research Communications of Chemical Pathology and Pharmacology.


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