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CANCER: COLO-RECTAL & Cannabis studies completed

Overview

Most colorectal cancers start in cells that line the inside of the colon or the rectum. Cannabis has a unique ability to fight many forms of cancer, including colon cancer.


Eating a diet high in fiber may help prevent colorectal cancer and other common digestive system cancers, including stomach, mouth, and pharynx. Fiber is found in fruits, vegetables, and whole grains. In general, the more natural and unprocessed the food, the higher it is in fiber.


Also see - Juicing cannabis as a method of use.

Medical Marijuana:
This is a useful agent for treating nausea, appetite loss, pain and insomnia that can occur as side effects of chemotherapy or cancer itself. Beyond that, some components of cannabis may have significant anti-cancer effects.

Science and Research

2014 - Study ~ Synthesis of Tetrahydrohonokiol Derivates and Their Evaluation for Cytotoxic Activity against CCRF-CEM Leukemia, U251 Glioblastoma and HCT-116 Colon Cancer Cells.

2014 - Study ~ Physiological intestinal oxygen modulates the Caco-2 cell model and increases sensitivity to the phytocannabinoid cannabidiol.

2013 - Patent ~ US Patent Application 20130059018 - PHYTOCANNABINOIDS IN THE
TREATMENT OF CANCER

2013 - Study ~ The Cannabinoid WIN 55,212-2 Decreases Specificity Protein (Sp) Transcription Factors and the Oncogenic Cap Protein eIF4E in Colon Cancer Cells.

2013 - Study ~ Inhibition of colon carcinogenesis by a standardized Cannabis sativa extract with high content of cannabidiol

2013 - Study ~ Honokiol as a Radiosensitizing Agent for Colorectal cancers.

2013 - Study ~ The Cannabinoid WIN 55,212-2 Decreases Specificity Protein Transcription Factors and the Oncogenic Cap Protein eIF4E in Colon Cancer Cells

2013 - News ~ Marijuana Verses Leading Pharmaceuticals In The Treatment of Colon Cancer

2012 - Study ~ Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer.

2012 - Study ~ Anti-tumor Activity of the Novel Hexahydrocannabinol Analog LYR-8 in Human Colorectal Tumor Xenograft Is Mediated through the Inhibition of Akt and Hypoxia-Inducible Factor-1α Activation.

2012 - Exerpt ~ How Weed Can Protect Us From Cancer and Alzheimer's

2012 - News ~   Study: Marijuana Could Stop Growth of Colon Cancer Cells

2011 - Study ~ Evaluation of the Cyclooxygenase Inhibiting Effects of Six Major Cannabinoids Isolated from Cannabis sativa

2011 - Study ~ Phytocannabinoids for use in the treatment of cancer - Patent GB2478595 (A) ― 2011-09-14

2011 - Study ~ Interaction of endocannabinoid system and steroid hormones in the control of colon cancer cell growth.

2011 - Study ~ Anandamide inhibits the growth of colorectal cancer cells through CB1 and lipid rafts

2011 - Study ~ Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent.

2010 - Study ~ The endogenous cannabinoid, anandamide, induces COX-2-dependent cell death in apoptosis-resistant colon cancer cells.

2010 - Study ~ Pharmacological effects of cannabinoids on the Caco-2 cell culture model of intestinal permeability.

2010 - Study ~ Effects of anandamide on polyamine levels and cell growth in human colon cancer cells

2010 - Study ~ Induction of p53-independent apoptosis by a novel synthetic hexahydrocannabinol analog is mediated via Sp1-dependent NSAID-activated gene-1 in colon cancer cells

2010 - Study ~ Involvement of NSAID-activated gene-1 in a novel synthetic hexahydrocannabinol analogue-induced growth inhibition and apoptosis of colon cancer cells

2009 - Study - Cannabinoids in intestinal inflammation and cancer

2009 - Study ~ Induction of the antitumorigenic NSAID-activated gene (NAG-1) in synthetic hexahydrocannabinol-induced apoptosis of human colorectal cancer cells

2009 - Study ~ Cannabinoid receptor-independent cytotoxic effects of cannabinoids in human colorectal carcinoma cells: synergism with 5-fluorouracil.

2009 - Study ~ Cannabinoids in intestinal inflammation and cancer

2008 - Study - Cannabis compound clue to colon cancer

2008 - Study ~ Increased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon.

2008 - Study ~ Cannabinoid receptor activation induces apoptosis through tumor necrosis factor alpha-mediated ceramide de novo synthesis in colon cancer cells.

2008 - Study ~ Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects

2008 - News - Marijuana takes on colon cancer

2008 - News - Cannabis-Linked Cell Receptor Might Help Prevent Colon Cancer

2008 - News ~ Turned-Off Cannabinoid Receptor Turns On Colorectal Tumor Growth

2008 - News ~ Cannabis-Linked Cell Receptor Might Help Prevent Colon Cancer

2008 - News ~ CANNABINOID RECEPTOR MAY PLAY ROLE IN SUPPRESSING TUMORS

2008 - News ~ Cannabinoid cell surface receptor plays a tumor-suppressing role in human colorectal cancer

2007 - Study ~ Opposing Actions of Endocannabinoids on Cholangiocarcinoma Growth :
RECRUITMENT OF Fas AND Fas LIGAND TO LIPID RAFTS

2007 - Study ~ The cannabinoid CB(2) receptor: a good friend in the gut.

2007 - Study ~ The cannabinoid delta(9)-tetrahydrocannabinol inhibits RAS-MAPK and PI3K-AKT survival signalling and induces BAD-mediated apoptosis in colorectal cancer cells.

2006 - Study ~ A cannabinoid quinone inhibits angiogenesis by targeting vascular endothelial cells.

2005 - Study - The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: a possible role for cyclooxygenase 2

2005 - Study - Cannabinoids and cancer: potential for colorectal cancer therapy.

2005 - Study ~ The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: a possible role for cyclooxygenase 2

2005 - Study ~ A new class of inhibitors of 2-arachidonoylglycerol hydrolysis and invasion of prostate cancer cells

2004 - Study ~ Inflammation and cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation.

2004 - Study ~ Anandamide is an endogenous inhibitor for the migration of tumor cells and T lymphocytes.

2003 - Study ~ Possible endocannabinoid control of colorectal cancer growth.


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