BETA-CARYOPHYLENE- (E)-BCP (phytocannabinoid, CB2 agonist) &
Cannabis Studies Completed
Cannabis Studies Completed
BCP is found in the essential oils of a variety of plants, including rosemary, hops, cloves and, of course, cannabis. It’s also highly present in black pepper.While BCP was first synthesized in 1964, it wasn’t until 2008 that a group of German and Swiss scientists, led by Andreas Zimmer, PhD and Ildiko Racz, PhD of the University of Bonn, discovered that BCP is a cannabinoid.
Caryophyllene, or-β-caryophyllene, is a natural bicyclic sesquiterpene that is a constituent of many essential oils, especially clove oil, the oil from the stems and flowers of Syzygium aromaticum, and cannabis plants.
Boiling point: 268 °C
Density: 905.20 kg/m³
Science and Research
2010 - News ~ Terpenes, Terpenoids and Cannabis.
2008 - Study - Beta-caryophyllene is a dietary cannabinoid.
2008 - Study ~ Anti-inflammatory cannabinoids in diet.
2008 - News ~ Salutary pizza spice.
seeds can be eaten raw, ground into a meal, sprouted, made into hemp
milk (akin to soy milk), prepared as tea, and used in baking.
Hemp-seed is usually very safe for those unable to tolerate nuts, gluten, lactose, and sugar.
In fact, there are no known allergies to hemp foods.
Hemp-seed contains no gluten and therefore would not trigger symptoms of celiac disease
The fresh leaves can also be eaten in salads. Products include cereals, frozen waffles, hemp tofu, and nut butters.
A few companies produce value added hemp seed items that include the seed oils, whole hemp grain (which is sterilized by law in the United States, where they import it from China and Canada), dehulled hemp seed (outer shell), hemp flour, hemp cake (a by-product of pressing the seed for oil) and hemp protein powder.
Hemp is also used in some organic cereals, for non-dairy milk somewhat similar to soy and nut milks, and for non-dairy hemp "ice cream."
44% of the weight of hemp-seed is healthy oils.
Beta-caryophyllene is a dietary cannabinoid
Proc Natl Acad Sci U S A. 2008 July 1; 105(26): 9099–9104.
Published online 2008 June 23. doi: 10.1073/pnas.0803601105.
(Fig. 1) is a major plant volatile found in large amounts in the essential oils of many different spice and food plants, such as oregano (Origanum vulgare L.), cinnamon (Cinnamomum spp.) and black pepper (Piper nigrum L.). In nature, (E)-BCP is usually found together with small quantities of its isomers (Z)-β-caryophyllene [(Z)-BCP or isocaryophyllene] and α-humulene (formerly α-caryophyllene) or in a mixture with its oxidation product, BCP oxide (Fig. 1). Because of its weak aromatic taste, (E)-BCP is commercially used as a food additive and in cosmetics. (E)-BCP is also a major component (up to 35%) in the essential oil of Cannabis sativa L). Although Cannabis contains >400 different secondary metabolites, including >65 cannabinoid-like natural products, only Δ9-tetrahydrocannabinol (THC), Δ8-tetrahydrocannabinol, and cannabinol have been reported to activate cannabinoid receptor types 1 (CB1) and 2 (CB2). Here, we show that the essential oil component (E)-BCP selectively binds to the CP55,940 binding site (i.e., THC binding site) in the CB2 receptor, leading to cellular activation and antiinflammatory effects.