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Angiogenesis (the formation of new blood vessels)
Angiogenesis (the formation of new blood vessels)
Overview
Angiogenesis is the formation of new blood vessels. This process involves the migration, growth, and differentiation of endothelial cells, which line the inside wall of blood vessels.
The process of angiogenesis is controlled by chemical signals in the body. These signals can stimulate both the repair of damaged blood vessels and the formation of new blood vessels.
Other chemical signals, called angiogenesis inhibitors, interfere with blood vessel formation.
Normally, the stimulating and inhibiting effects of these chemical signals are balanced so that blood vessels form only when and where they are needed.

Cannabis Science and Medical Research Articles
2003 - Study ~ Inhibition of tumor angiogenesis by cannabinoids
2006 - Study ~ A cannabinoid quinone inhibits angiogenesis by targeting vascular endothelial cells.
2007 - Review - Endocannabinoids as emerging suppressors of angiogenesis and tumor invasion
2007 - Study ~ Antiangiogenic activity of the endocannabinoid anandamide: correlation to its tumor- suppressor efficacy.
2008 - Study ~ Local administration of WIN 55,212-2 reduces chronic granuloma-associated angiogenesis in rat by inhibiting NF-kappaB activation.
2008 - Study ~ Cannabinoids reduce granuloma-associated angiogenesis in rats by controlling transcription and expression of mast cell protease-5.
2010 - Study ~ Diabetic retinopathy: Role of inflammation and potential therapies for anti-inflammation.
2010 - Study ~ Endocannabinoid-like N-arachidonoyl serine is a novel pro-angiogenic mediator.
2010 - Study ~ Angiogenesis: a new physiological role for N-arachidonoyl serine and GPR55?
2011 - Study ~ Genetic and pharmacological inactivation of cannabinoid CB1 receptor inhibits angiogenesis.
2011 - Study ~ Novel hexahydrocannabinol analogs as potential anti-cancer agents inhibit cell proliferation and tumor angiogenesis.
2012 - Study ~ Cannabidiol inhibits angiogenesis by multiple mechanisms.
2012 - Study ~ Cannabinoid receptor 2 agonist ameliorates mesenteric angiogenesis and portosystemic collaterals in cirrhotic rats.
2013 - Study - Suppression of vascular endothelial growth factor expression by cannabinoids in a canine osteosarcoma cell line
2013 - Study ~ A new strategy to block tumor angiogenesis by inhibiting endocannabinoid inactivation
2013 - Study ~ Autophagy triggered by magnolol derivative negatively regulates angiogenesis.
2013 - Study ~ Magnolol suppresses hypoxia-induced angiogenesis via inhibition of HIF-1α/VEGF signaling pathway in human bladder cancer cells