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Listen RedEye-O Audio: Cannabis Maintenance as Addiction Treatment
ADDICTION RISK & Cannabis Studies
Overview
In 2010, 16,652
overdose
deaths were directly related to prescribed medications. namely opioid based. While doctors prescribed these lethal narcotics, some estimates suggest that up to 70% of these medications get re-sold on the streets.
A study of 4000 indicates that cannabis discourages use of alcohol and hard drugs.
A study of 4000 indicates that cannabis discourages use of alcohol and hard drugs.
Science & Research
2014 - Study ~ Pregnenolone can protect the brain from cannabis intoxication. PubMed
2014 - Study ~ Evaluation of WIN 55,212-2 self-administration in rats as a potential cannabinoid abuse liability model. Pharmacology, Biochemistry and Behavior.
2014 - Study ~ Nabiximols as an agonist replacement therapy during cannabis withdrawal: a randomized clinical trial. Jama Psychiatry.
2014 - Study ~ Potential role of N-acetylcysteine in the management of substance use disorders. CNS Drugs.
2014 - Study ~ Prevalence and correlates of alcohol and cannabis use disorders in
the United States: results from the national longitudinal study of
adolescent health. PubMed
2014 - Study ~ Cannabis withdrawal in chronic, frequent cannabis smokers during sustained abstinence within a closed residential environment. American Journal of Addictions.
2014 - Study ~ Relationship between working-memory
network function and substance use: a 3-year longitudinal fMRI study in
heavy cannabis users and controls. Addiction Biology.2014 - News ~ Hormone shows promise at negating marijuana's high effect. CBS News.
2014 - News ~ Muting Marijuana's High: Pot Without the Impairment. Time Health.2013 - Study ~ Implicit associations and explicit expectancies toward cannabis in heavy cannabis users and controls. Frontiers in Psychiatry.
2013 - Study ~ The Global Epidemiology and Contribution of Cannabis Use and Dependence to the Global Burden of Disease. PLOS
2013 - Study ~ The Interplay between Parental Monitoring and the Dopamine D4 Receptor Gene in Adolescent Cannabis Use. PLOS.
2013 - Study ~ Inhibition of FAAH and activation of PPAR: new approaches to the treatment of cognitive dysfunction and
drug addiction. Pharmacology Therapeutics.
2013 - Study ~ Endocannabinoids underlie reconsolidation of hedonic memories in Wistar rats. Psychopharmacology (Berl).
2013 - Study ~ Lipids and addiction: how sex steroids, prostaglandins, and cannabinoids interact with drugs of abuse. New York Academy of Science.
2013 - Study ~ Role of intra-accumbal cannabinoid CB1 receptors in the
potentiation, acquisition and expression of morphine-induced conditioned
place preference. Behavioral Brain Research.
2013 - Study ~ Probability and predictors of transition from abuse to dependence on alcohol, cannabis, and cocaine: results from the National Epidemiologic Survey on Alcohol and Related Conditions. American Journal of Drug and Alcohol Abuse.
2013 - Study ~ Probability and predictors of transition from abuse to dependence on alcohol, cannabis, and cocaine: results from the National Epidemiologic Survey on Alcohol and Related Conditions. American Journal of Drug and Alcohol Abuse.
2013 - Study ~ Dysregulation of cannabinoid CB1 receptor and associated signaling
networks in brains of cocaine addicts
and cocaine-treated rodents. Neuroscience.
2013 - Study ~ Male and female rats differ in brain cannabinoid CB1 receptor density and function and in behavioural traits predisposing to drug addiction: effect of ovarian hormones. Current Pharmaceutical Design.
2013 - Study ~ Male and female rats differ in brain cannabinoid CB1 receptor density and function and in behavioural traits predisposing to drug addiction: effect of ovarian hormones. Current Pharmaceutical Design.
2013 - Study ~ Palmitoylethanolamide: from endogenous cannabimimetic substance to innovative medicine for the treatment of
cannabis dependence. Medical Hypotheses.
2013 - Study ~ Reducing cannabinoid abuse and preventing relapse by enhancing endogenous brain levels of kynurenic acid. Nature Neuroscience.
2013 - Study ~ Impulsivity, variation in the cannabinoid receptor (CNR1) and fatty
acid amide hydrolase (FAAH) genes, and
marijuana-related problems. Journal of Studies on Alcohol and Drugs.
2013 - Study ~ Neural responses to subliminally presented cannabis and other emotionally evocative cues in cannabis-dependent individuals. Psychopharmacology (Berl).
2013 - Study ~ Endocannabinoids underlie reconsolidation of hedonic memories in Wistar rats. Psychopharmacology (Berl).
2013 - Study ~ Cannabis cue reactivity and craving among never, infrequent and heavy cannabis users. Neuropsychopharmacology.
2013 - Study ~ Cannabis withdrawal syndrome: An important diagnostic consideration in adolescents presenting with
disordered eating. International Journal of Eating Disorders.
2013 - Study ~ Low-frequency stimulation evokes serotonin release in the nucleus
accumbens and induces long-term depression via production of
endocannabinoid. Journal of Neurophysiology.
2013 - Study ~ Further evidence for association of polymorphisms in the CNR1 gene with cocaine addiction: confirmation in an independent sample and meta-analysis. Addiction Biology.
2013 - Study ~ The effects of cannabis use expectancies on self-initiated cannabis cessation. Center for Innovation to Implementation.
2013 - Study ~ Cannabis as a substitute
for alcohol and other drugs: A dispensary-based survey of substitution
effect in Canadian medical
cannabis patients. Journal
of Addiction Research & Theory.
2012 - Study ~ Medical marijuana laws in 50 states: investigating the relationship
between state legalization of medical marijuana and marijuana use, abuse
and dependence.
2012 - Study ~ A double-blind randomized controlled trial of N-acetylcysteine in cannabis-dependent adolescents.
2012 - Study ~ The genetic basis of the endocannabinoid system and drug addiction in humans. Journal of Pharmacology.
2012 - Study ~ Involvement of the endocannabinoid system in reward processing in the human brain. US National Library of Medicine, National Institutes of Health.
2012 - Study ~ A genetic perspective on the proposed inclusion of cannabis withdrawal in DSM-5. Psychological Medicine.2012 - Study ~ Reduction of dependence to cannabinoids by GLT-1 activating property of the beta-lactam antibiotic. Medical Hypotheses.
2012 - Study ~ Human abuse potential and cognitive effects of taranabant, a
cannabinoid 1 receptor inverse agonist: a randomized, double-blind,
placebo- and active-controlled, crossover study in recreational polydrug
users. Journal of Clinical Psychopharmacology.
2012 - Study ~ Anandamide and 2-arachidonoylglycerol: pharmacological properties,
functional features, and emerging specificities of the two major
endocannabinoids. Molecular Neurobiology.
2011 - Study ~ Aerobic Exercise Training Reduces Cannabis Craving and Use in
Non-Treatment Seeking Cannabis-Dependent Adults. Vanderbilt University, Nashville, Tennessee, United States of
America, University of Granada, Spain.
2011 - Study ~ Abuse potential and psychoactive effects of δ-9-tetrahydrocannabinol
and cannabidiol oromucosal spray (Sativex), a new cannabinoid medicine. Expert Opinion on Drug Safety.
2011 - Study ~ Dronabinol for the Treatment of Cannabis Dependence: A Randomized, Double-Blind, Placebo-Controlled Trial. National Institutes of Health.
2011 - Study ~ The genetic basis of the endocannabinoid system and drug addiction in humans. Journal of Psychopharmacology.
2011 - News ~ Exercise can reduce cannabis use in persons who don't want to stop. Medical Life Sciences.
2010 - Study ~ Medical marijuana users in substance abuse treatment. Harm Reduction Journal.2005 - Study ~ Alcohol Consumption Moderates the Link Between Cannabis Use and Cannabis Dependence
2010 - News ~ Teen Pot Smoking Won't Lead to Other Drugs as Adults. WebMD.
in maternally deprived rats. Neuropsychopharmacology.
2009 - News ~ Active Ingredient In Cannabis Eliminates Morphine Dependence In Rats. Science Daily.
2009 - News ~ Four percent of adults worldwide using cannabis. Medical Press.
2009 - News ~ For pot users, visual and audible cues set off cravings. Technica.
2009 - News ~ The use and misuse of alcohol and marijuana can be traced to a common set of genes. Eurek Alert.
2009 - News ~ The Surprising Effect Of Marijuana On Morphine Dependence. Red Orbit.2008 - Excerpt ~ Psychologic dependence can develop with chronic use, but very little physical dependence is clinically apparent. Merck Manual
2008 - News ~ Calling B.S. on the Idea of 'Marijuana Addiction'. Alternet
2008 - News ~ Study of 4000 indicates
marijuana discourages use
of hard drugs. Common Sense for Drug Policy.
2007 - Study ~ The fatty acid amide hydrolase C385A (P129T) missense variant in
cannabis users: studies of drug use and dependence in Caucasians. American Journal of Medical Genetics.
2007 - Study ~ Long
term marijuana users seeking medical cannabis in California
(2001–2007): demographics, social characteristics, patterns of cannabis
and other drug use of 4117 applicants. Harm Reduction Journal.
2007 - Study ~ Lack of behavioral sensitization after repeated exposure to THC in mice and comparison to methamphetamine. Psychopharmacology.
2006 - Study ~ Confirming alcohol-moderated links between cannabis use and dependence in a national sample. Science Direct.in an Internet Survey. American Psychological Association.
2004 - Study ~ Human
cannabinoid receptor 1: 5′ exons, candidate regulatory regions,
polymorphisms, haplotypes and association
with polysubstance abuse. Molecular Psychiatry.
2004 - Study ~ Review of the validity and significance of cannabis withdrawal syndrome. American Journal of Psychiatry.
2004 - Study ~ Cannabis abuse is not a risk factor for treatment outcome in
methadone maintenance treatment:
a 1-year prospective study in an
Israeli clinic. Australian and New Zealand Journal of Psychiatry.
2003 - Study ~ Chronic Morphine Modulates the Contents of the Endocannabinoid, 2-Arachidonoyl Glycerol, in Rat Brain. Neuropsychopharmacology. 2003 - Study ~ Does Cannabis Use Predict Poor Outcome for
Heroin-Dependent Patients on Maintenance Treatment? A Review of Past
Findings, and More Evidence Against. Addiction, D.H. Epstein and K.L. Preston
2001 - Study ~ Delta9-tetrahydrocannabinol releases and facilitates the effects of
endogenous enkephalins: reduction in morphine withdrawal syndrome
without change in rewarding effect. European Journal of Neuroscience.
1998 - Study ~ Anandamide, an Endogenous Cannabinoid, Has a Very Low Physical Dependence Potential. Journal of Pharmacology and Experimental Therapeutics.1998 - Study ~ Abuse potential of Dronabinol (Marinol). Journal of Psychoactive Drugs.
1997 - Study ~ Cannabis dependence, withdrawal, and reinforcing effects among adolescents with conduct symptoms and
substance use disorders. Science Direct.
1996 - Study ~ Genetic differences in delta 9-tetrahydrocannabinol-induced
facilitation of brain stimulation reward as measured by a rate-frequency
curve-shift electrical brain stimulation paradigm in three different
rat strains. Life Sciences.1980 - Study ~ An abstinence syndrome following chronic administration of delta-9-terahydrocannabinol in rhesus monkeys. Psychopharmacology (Berl).