Cannabis Health Science Studies Index

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THC/ TETRAHYDROCANNABINOL & Cannabis studies completed

Overview

(THC), also known as delta-9-tetrahydrocannabinol, is the principal psychoactive constituent of the cannabis plant, and first isolated in 1964 by Israeli scientists Raphael Mechoulam, Yechiel Gaoni and colleagues at the Hebrew University of Jerusalem.

Science & Research

Updated - News ~ Phytocannabinoids.

Updated - Transcript ~ Tetrahydrocannabinol- an interview with Akshat Rathi.

1946 - Study ~ Studies on the pharmacology and acute toxicity of compounds with marijuana activity.

1964 - 1st page Study ~ Isolation, Structure, and Partial Synthesis of an Active Constituent of Hashish.

1970 - Study ~ Chemical basis of hashish activity.

1971 - Study ~ Activity of Dgr8-and Dgr9-Tetrahydrocannabinol and Related Compounds in the Mouse.

1971 - Study ~ Some actions of delta-1 tetrahydrocannabinol and cannabidiol at cholinergic junctions.

1972 - Study ~ A metabolic interaction in vivo between cannabidiol and Δ1-tetrahydrocannabinol.

1972 - Study ~ Water-soluble derivatives of 1 -tetrahydrocannabinol.

1973 - Study ~ Effect of Biogenic Amines and Cannabinoids on Bacterial Chemotaxis.

1974 - Study ~ Acute effects of smoked marijuana and oral delta9-tetrahydrocannabinol on specific airway conductance in asthmatic subjects.

1974 - Study ~ A pilot study of orally administered Δ1-trans-tetrahydrocannabinol in the management of patients undergoing radiotherapy for carcinoma of the bronchus.

1974 - Study ~ Effects of marihuana in laboratory animals and in man.

1974 - Study ~ Smoked marijuana and oral delta-9-THC on specific airway conductance in asthmatic subjects.

1975 - Study ~ Absence of interaction between delta9-tetrahydrocannabinol (delta-THC) and cannabidiol (CBD) in aggression, muscle control and body temperature experiments in mice.

1975 - Study ~ Analgesic effect of delta-9-tetrahydrocannabinol.

1975 - Study ~ Antiepileptic and prophylactic effects of tetrahydrocannabinols in amygdaloid kindled cats.

1975 - Study ~ Effects of smoked marijuana in experimentally induced asthma.

1975 - Study ~ Interactions in man of delta-9-tetrahydrocannabinol. II. Cannabinol and cannabidiol.

1975 - Study ~ Intravenous delta9-Tetrahydrocannabinol: Effects of ventilatory control and cardiovascular dynamics.

1975 - Study ~ The analgesic properties of delta-9-tetrahydrocannabinol and codeine.

1975 - Study ~ The influence of delta9-tetrahydrocannabinol, cannabinol and cannabidiol on tissue oxygen consumption.

1976 - Study ~ Antibacterial activity of delta9-tetrahydrocannabinol and cannabidiol.

1976 - Study ~ Anticonvulsant activity of delta9-tetrahydrocannabinol compared with three other drugs.

1976 - Study ~ Bronchodilator effect of delta1-tetrahydrocannabinol administered by aerosol of asthmatic patients.

1977 - Study ~ Bronchial effects of aerosolized delta 9-tetrahydrocannabinol in healthy and asthmatic subjects.

1977 - Study ~ In vivo effects of cannabinoids on macromolecular biosynthesis in Lewis lung carcinomas.

1979 - Study ~ Delta-9-Tetrahydrocannibinol as an Antiemetic in Cancer Patients Receiving High-Dose Methotrexate.

1980 - Study ~ Marihuana as a therapeutic agent for muscle spasm or spasticity.

1980 - Study ~ Plasma delta-9-tetrahydrocannabinol concentrations and clinical effects after oral and intravenous administration and smoking.

1981 - Study ~ Activity of cannabis in relation to its delta'-trans-tetrahydro-cannabinol content.

1981 - Study ~ Sedative activity of cannabis in relation to its delta'-trans-tetrahydrocannabinol and cannabidiol content.

1981 - Study ~ The cardiovascular and autonomic effects of repeated administration of delta-9-tetrahydrocannabinol to rhesus monkeys.

1981 - Study ~ The seed and the soil: effect of dosage, personality and starting state on the response to delta 9 tetrahydrocannabinol in man.

1982 - Study ~ Comparison of effects of marihuana cigarettes of three different potencies.

1982 - Study ~ Ocular Effects of Topical Administration of {Delta}9-Tetrahydrocannabinol in Man.

1983 - Study ~ Allergenic properties of naturally occurring cannabinoids.

1983 - Study ~ Multiple-Drop Study of Topically Applied 1% {Delta}9-Tetrahydrocannabinol in Human Eyes.

1983 - Study ~ Neurobehavioral actions of cannabichromene and interactions with delta 9-tetrahydrocannabinol.

1983 - Study ~ Respiratory and cardiovascular depressant effects of nabilone, N-methyllevonantradol and delta 9-tetrahydrocannabinol in anesthetized cats.

1984 - Study ~ Acute Effects of Natural and Synthetic Cannabis Compounds on Prolactin Levels in Human Males.

1984- Study ~ Inhibition of neuroblastoma adenylate cyclase by cannabinoid and nantradol compounds.

1984 - Study ~ Intraocular pressure, ocular toxicity and neurotoxicity after administration of delta 9-tetrahydrocannabinol or cannabichromene.

1984 - Study ~ Ocular hypotension, ocular toxicity, and neurotoxicity in response to marihuana extract and cannabidiol.

1985- Study ~ Antiemetic efficacy of levonantradol compared to delta-9-tetrahydrocannabinol for chemotherapy-induced nausea and vomiting.

1985- Study ~ The quasi-morphine withdrawal syndrome: effect of cannabinol, cannabidiol and tetrahydrocannabinol.

1986- Study ~ The effect of delta-9-THC on human spasticity.

1987- Study ~ UV-B RADIATION EFFECTS ON PHOTOSYNTHESIS, GROWTH and CANNABINOID PRODUCTION OF TWO Cannabis sativa CHEMOTYPES.

1988- Study ~ Oral vs. Inhaled Cannabinoids for Nausea/Vomiting from Cancer Chemotherapy.

1989- Study ~ The inhibitory effects of cannabinoids, the active constituents of Cannabis sativa L. on human and rabbit platelet aggregation.

1990- Study ~ A comparison of the ocular and central effects of delta 9-tetrahydrocannabinol and cannabigerol.

1990- Study ~ Delta-9-tetrahydrocannabinol shows antispastic and analgesic effects in a single case double-blind trial.

1990- Study ~ Marijuana Smoking: Factors That Influence the Bioavailability of Tetrahydrocannabinol.

1991- Study ~ Chronic Exposure to Delta 9-tetrahydrocannabinol Fails to Irreversibly Alter Brain Cannabinoid Receptors.

1992- Study ~ Cannabinoid receptor agonists inhibit Ca current in NG108-15 neuroblastoma cells via a pertussis toxin-sensitive mechanism.

1993- Study ~ Cross-tolerance between delta-9-tetrahydrocannabinol and the cannabimimetic agents, CP 55,940, WIN 55,212-2 and anandamide.

1994- Study ~ Effects of delta 9-THC on marijuana smoking, dose choice, and verbal report of drug liking.

1994- Study ~ Interactions between delta 9-tetrahydrocannabinol and kappa opioids in mice.

1995- Study ~ Anandamide and delta 9-THC dilation of cerebral arterioles is blocked by indomethacin.

1995- Study ~ Cannabinoid precipitated withdrawal by the selective cannabinoid receptor antagonist, SR 141716A.

1996 - Study ~ Genetic differences in delta 9-tetrahydrocannabinol-induced facilitation of brain stimulation reward as measured by a rate-frequency curve-shift electrical brain stimulation paradigm in three different rat strains.

1996- Study ~ NTP Technical Report on the Toxicology and Carcinogenesis Studies of 1-Trans-Delta9-Tetrahyrdocannabinol (CAS No. 1972-08-3) in F344/N Rats and B6C3F1 Mice (Gavage Studies).

1996 - Study ~ The effect of orally and rectally administered delta-9-tetrahydrocannabinol on spasticity : a pilot study with 2 patients.

1996 - Study ~ Toxicity and Carcinogenicity of {Delta}9-Tetrahydrocannabinol in Fischer Rats and B6C3F1 Mice.

1997 - Study ~ Immunochemical localization of tetrahydrocannabinol (THC) in cryofixed glandular trichomes of Cannabis (Cannabaceae).

1997 - Study ~ The perceived effects of smoked cannabis on patients with multiple sclerosis.

1997 - News ~ Study: THC Not Cancer-Causing.

1998 - Study ~ Cannabidiol and (−)Δ9-tetrahydrocannabinol are neuroprotective antioxidants.

1998 - Study ~ Cerebellar activity and disturbed time sense after THC.

1999 - Study ~ Cannabis and cannabinoids: pharmacology and rationale for clinical use.

1999 - Study ~ Cannabis: Discrimination of "Internal Bliss"?

1999 - Letter ~ Treatment of Tourette's Syndrome With Delta-9-Tetrahydrocannabinol.

2000 - Study ~ Advantages of polypharmaceutical herbal cannabis compared to single ingredient, synthetic tetrahydrocannabinol.

2000 - Study ~ Anti-tumoral action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation.

2000 - Study ~ Cannabinoids in clinical practice.

2000 - Study ~ Cannabinoids might reduce spasticity in multiple sclerosis.

2000 - Study ~ Endogenous cannabinoids and appetite.

2000 - Study ~ GC-MS analysis of the total delta9-THC content of both drug- and fiber-type cannabis seeds.

2000 - Study ~ Variations of D9-THC content in single plants of hemp varieties.

2001 - Study ~ Clinical investigation of delta-9-tetrahydrocannabinol (THC) as an alternative therapy for overactive bladders in spinal cord injury (SCI) patients.

2001 - Study ~ Delta(9)-tetrahydrocannabinol and synthetic cannabinoids prevent emesis produced by the cannabinoid CB(1) receptor antagonist/inverse agonist SR 141716A.

2001 - Study ~ Neuroprotection by Delta 9-Tetrahydrocannabinol, the Main Active Compound in Marijuana, against Ouabain-Induced In Vivo Excitotoxicity.

2001 - Study ~ Tetrahydrocannabinol for treatment of chronic pain.

2002 - Study ~ Cannabinoids and multiple sclerosis.

2002 - Study ~ Cannabinoids in the treatment of pain and spasticity in multiple sclerosis.

2002 - Study ~ Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease.

2002 - Study ~ The potent emetogenic effects of the endocannabinoid, 2-AG (2-arachidonoylglycerol) are blocked by delta(9)-tetrahydrocannabinol and other cannnabinoids.

2003 - Study ~ Cannabinoid CB2 receptor activation reduces mouse myocardial ischemia-reperfusion injury: involvement of cytokine/chemokines and PMN.

2003 - Study ~ Cannabinoid influences on palatability: microstructural analysis of sucrose drinking after delta(9)-tetrahydrocannabinol, anandamide, 2-arachidonoyl glycerol and SR141716.

2003 - Study ~ Cannabinoids: Potential Anticancer Agents.

2003 - Study ~ Cannabis and the brain.

2003 - News ~ Cannabis can help MS sufferers.

2003 - Study ~ Cannabis use for chronic non-cancer pain: results of a prospective survey.

2003 - Study ~ Delta 9-tetrahydrocannabinol (THC) is effective in the treatment of tics in Tourette syndrome: a 6-week randomized trial.

2003 - Study ~ Effects of THC on Behavioral Measures of Impulsivity in Humans.

2003 - Study ~ Inhibition of tumor angiogenesis by cannabinoids.

2003 - Study ~ The Endogenous Cannabinoid System Regulates Seizure Frequency and Duration in a Model of Temporal Lobe Epilepsy.

2003 - Study ~ The treatment of spasticity with D9-THC) in patients with spinal cord injury.

2003 - Study ~ Treatment of Tourette Syndrome with Delta-9-Tetrahydrocannabinol (Delta9-THC): No Influence on Neuropsychological Performance.

2004 - Study ~ [123I] AM281 single-photon emission computed tomography imaging of central cannabinoid CB1 receptors before and after Delta9-tetrahydrocannabinol therapy and whole-body scanning for assessment of radiation dose in tourette patients.

2004 - Study ~ Cannabinoids: Defending the Epileptic Brain.

2004 - Study ~ Differential Effects of THC or CBD-rich Cannabis Extracts on Working Memory in Rats.

2004 - Study ~ Effect of Delta-9-tetrahydrocannabinol and cannabidiol on nocturnal sleep and early-morning behavior in young adults.

2004 - Study ~ Initial experiences with medicinal extracts of cannabis for chronic pain: Results from 34 ‘N of 1’ studies.

2004 - Study ~ The good and the bad effects of (−) trans-delta-9-tetrahydrocannabinol (Δ9-THC) on humans.

2004 - Study ~ Very low doses of delta 8-THC increase food consumption and alter neurotransmitter levels following weight loss.

2004 - News ~ THC in marijuana may block the spread of forms of cancer causing herpes viruses.

2004 - News ~ Cannabis truly helps multiple sclerosis sufferers. (may need registration)

2004 - News ~ Marijuana-like compounds may aid array of debiliating conditions ranging from Parkinson's to pain.

2005 - Study ~ Low dose oral cannabinoid therapy reduces progression of atherosclerosis in mice.

2005 - Study ~ Protective effects of Δ9-tetrahydrocannabinol against N-methyl-D-aspartate-induced AF5 cell death.

2005 - Study ~ Synergistic Interactions between Cannabinoids and Environmental Stress in the Activation of the Central Amygdala.

2005 - Study ~ The effects of Δ9-tetrahydrocannabinol in rat mesenteric vasculature, and its interactions with the endocannabinoid anandamide.

2005 - News ~ Cannabis may help keep arteries clear.

2005 - News ~ Cannabis Spray for Bipolar.

2005 - News ~ Chemicals in Cannabis may help mentally ill.

2005 - News ~ Medical marijuana: study shows that THC slows atherosclerosis.

2005 - News ~ New Synthetic Delta-9-THC Inhaler Offers Safe, Rapid Delivery , Phase I Study.

2005 - News ~ Science: THC slows development of atherosclerosis in animal study.

2005 - News ~ THC effective in appetite and weight loss in severe lung disease (COPD).

2006 - Study ~ Δ9-Tetrahydrocannabinol-Induced Apoptosis in Jurkat Leukemia T Cells Is Regulated by Translocation of Bad to Mitochondria.

2006 - Study ~ An Experimental Study of Catechol-O-Methyltransferase Val(158)Met Moderation of Delta-9-Tetrahydrocannabinol-Induced Effects on Psychosis and Cognition.

2006 - Study ~ A pilot clinical study of Delta(9)-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme.

2006 - Study ~ A tale of two cannabinoids:The therapeutic rationale for combining tetrahydrocannabinol and cannabidiol.

2006 - Study ~ Cannabinoids and the Endocannabinoid System.

2006 - Study ~ Comparison of orally administered cannabis extract and delta-9-tetrahydrocannabinol in treating patients with cancer-related anorexia-cachexia syndrome: a multicenter, phase III, randomized, double-blind, placebo-controlled clinical trial from the Cannabis-In-Cachexia-Study-Group.

2006 - Study ~ Delta-9-THC based monotherapy in fibromyalgia patients on experimentally induced pain, axon reflex flare, and pain relief.

2006 - Study ~ Delta}9-Tetrahydrocannabinol Inhibits Cell Cycle Progression in Human Breast Cancer Cells through Cdc2 Regulation.

2006 - Study ~ Delta(9)-Tetrahydrocannabinol protects hippocampal neurons from excitotoxicity.

2006 - Study ~ Differential effects of cannabis extracts and pure plant cannabinoids on hippocampal neurones and glia.

2006 - Study ~ Further Characterization of the Time-Dependent Vascular Effects of Δ9-Tetrahydrocannabinol.

2006 - Study ~ The Cannabinoid Cb1 Receptor Antagonist Rimonabant Attenuates the Hypotensive Effect of Smoked Marijuana in Male Smokers.

2006 - Study ~ Marijuana's Active Ingredient Shown to Inhibit Primary Marker of Alzheimer's Disease.

2006 - Study ~ Methods evaluating cannabinoid and endocannabinoid effects on gastrointestinal functions.

2006 - Study ~ The effects of cannabinoids on P-glycoprotein transport and expression in multidrug resistant cells.

2006 - Study ~ The treatment of spasticity with Delta(9)-tetrahydrocannabinol in persons with spinal cord injury.

2006 - News ~ Cannabis destroys cancer cells.

2006 - News ~ THC and prochlorperazine effective in reducing vomiting in women following breast surgery.

2006 - News ~ THC inhibits primary marker of Alzheimer's disease.

2007 - Study ~ Δ9-Tetrahydrocannabinol (THC) and AM 404 protect against cerebral ischaemia in gerbils through a mechanism involving cannabinoid and opioid receptors.

2007 - Study ~ Anandamide and Delta9-tetrahydrocannabinol directly inhibit cells of the immune system via CB2 receptors.

2007 - Study ~ CB2 receptors in the brain: role in central immune function.

2007 - Study ~ Cross-sensitization and cross-tolerance between exogenous cannabinoid antinociception and endocannabinoid-mediated stress-induced analgesia.

2007 - Study ~ Delta(9)-tetrahydrocannabinol (Delta(9)-THC) prevents cerebral infarction via hypothalamic-independent hypothermia.

2007 - Study ~ Effects of a Selective Cannabinoid Agonist and Antagonist on Body Temperature in Rats.

2007 - Study ~ Low dose combination of morphine and Δ9-tetrahydrocannabinol circumvents antinociceptive tolerance and apparent desensitization of receptors.

2007 - Study ~ Medicinal chemistry endeavors around the phytocannabinoids.
2007 - Study ~ On the pharmacological properties of Delta9-tetrahydrocannabinol.

2007 - Study ~ Opioid Antagonism of Cannabinoid Effects: Differences between Marijuana Smokers and Nonmarijuana Smokers.

2007 - Study ~ Repeated Treatment with Cannabidiol but Not Delta9-tetrahydrocannabinol Has a Neuroprotective Effect Without the Development of Tolerance.

2007 - Study ~ Symptomatic treatment of multiple sclerosis using cannabinoids: recent advances.

2007 - Study ~ Synergy between Delta(9)-tetrahydrocannabinol and morphine in the arthritic rat.

2007 - Study ~ THC improves appetite and reverses weight loss in AIDS patients.

2007 - Study ~ The antinociceptive effect of Delta9-tetrahydrocannabinol in the arthritic rat involves the CB(2) cannabinoid receptor.
2007 - Study ~ The cannabinoid delta(9)-tetrahydrocannabinol inhibits RAS-MAPK and PI3K-AKT survival signalling and induces BAD-mediated apoptosis in colorectal cancer cells.

 2007 - Study ~ The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin.

 2007 - Study ~ The psychoactive plant cannabinoid, Delta9-tetrahydrocannabinol, is antagonized by Delta8- and Delta9-tetrahydrocannabivarin in mice in vivo.

2007 - News ~ Cannabis can reduce Allergic Skin Reactions, latest research shows.

2007 - News ~ Pot's Active Ingredient Halts Lung Cancer Growth, Study Says.

2008 - Study ~ Δ9-Tetrahydrocannabinol Content of Commercially Available Hemp Products.

2008 - Study ~ Antibacterial cannabinoids from Cannabis sativa: a structure-activity study.

2008 - Study ~ Attenuation of Experimental Autoimmune Hepatitis by Exogenous and Endogenous Cannabinoids: Involvement of Regulatory T Cells.

2008 - Study ~ Cannabinoids in the management of difficult to treat pain.

2008 - Study ~ Cannabinoid receptors in acute and chronic complications of atherosclerosis.

2008 - Study ~ Delta-9-tetrahydrocannabinol pharmacokinetics.

2008 - Study ~ Divergent effects of cannabidiol on the discriminative stimulus and place conditioning effects of Δ9-tetrahydrocannabinol.

2008 - Study ~ Effect of intrapulmonary tetrahydrocannabinol administration in humans.

2008 - Study ~ High concentrations of cannabinoids activate apoptosis in human U373MG glioma cells.

2008 - Study ~ The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin.

2008 - News ~ CSI: fingerprinting and drug detection in one.

2008 - News ~ Science: THC reduces reflux of acid from the stomach.

2009 - Study ~ Actions of delta-9-tetrahydrocannabinol in cannabis.

2009 - Study ~ Cannabidiol reverses the reduction in social interaction produced by low dose Delta(9)-tetrahydrocannabinol in rats.

2009 - Study ~ Cannabinoids Δ9-Tetrahydrocannabinol and Cannabidiol Differentially Inhibit the Lipopolysaccharide-activated NF-κB and Interferon-β/STAT Proinflammatory Pathways in BV-2 Microglial Cells.

2009 - Study ~ Cannabinoids, Endocannabinoids, and Related Analogs in Inflammation.

2009 - Study ~ Cannabinoid action induces autophagymediated cell death through stimulation of ER stress in human glioma cells.

2009 - Study ~ Cannabinoid Receptor 1 Binding Activity and Quantitative Analysis of Cannabis sativa L. Smoke and Vapor.

2009 - Study ~ Cannabinoid receptor 1 is a potential drug target for treatment of translocation-positive rhabdomyosarcoma.

2009 - Study ~ Delta 9-tetrahydrocannabinol induces dopamine release in the human striatum.

2009 - Study ~ Evaluation of Prevalent Phytocannabinoids in the Acetic Acid Model of Visceral Nociception.

2009 - Study ~ Hydroxylation and Further Oxidation of Δ9-Tetrahydrocannabinol by Alkane-Degrading Bacteria.

2009 - Study ~ Modulation of effective connectivity during emotional processing by Delta9-tetrahydrocannabinol and cannabidiol.

2009 - Study ~ Neurocognitive performance during acute THC intoxication in heavy and occasional cannabis users.

2009 - Study ~ Opposite Effects of Delta-9-Tetrahydrocannabinol and Cannabidiol on Human Brain Function and Psychopathology.

2009 - Study ~ Tetrahydrocannabinol (Delta 9-THC) Treatment in Chronic Central Neuropathic Pain and Fibromyalgia Patients: Results of a Multicenter Survey.

2009 - Study ~ Synthetic and plant-derived cannabinoid receptor antagonists show hypophagic properties in fasted and non-fasted mice.

2009 - Study ~ TRB3 links ER stress to autophagy in cannabinoid anti-tumoral action.

2009 - News ~ Active cannabis chemicals halt prostate cancer cell growth.

2009 - News ~ Active Component Of Marijuana Has Anti-Cancer Effects, Study Suggests.

2009 - News ~ Marijuana Chemicals Ease MS Symptoms, Review Confirms.

2009 - News ~ THC initiates brain cancer cells to destroy themselves.

2010 - Study ~ A behavioural comparison of acute and chronic Delta9-tetrahydrocannabinol and cannabidiol in C57BL/6JArc mice.

2010 - Study ~ Antidepressant-like effect of Delta(9)-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L.

2010 - Study ~ Antitumorigenic Effects of Cannabinoids beyond Apoptosis.

2010 - Study ~ Cannabinoid receptor CB1 mediates baseline and activity-induced survival of new neurons in adult hippocampal neurogenesis.

2010 - Study ~ Cannabinoids Inhibit Cellular Respiration of Human Oral Cancer Cells.

2010 - Study ~ Chronic cannabinoid administration lowers viral replication in lymph nodes of SIV infected Rhesus macaques.

2010 - Study ~ Delta9-tetrahydrocannabinol is a full agonist at CB1 receptors on GABA neuron axon terminals in the hippocampus.

2010 - Study ~ Disposition of Cannabichromene, Cannabidiol, and Δ9-Tetrahydrocannabinol and its Metabolites in Mouse Brain following Marijuana Inhalation Determined by High-Performance Liquid Chromatography-Tandem Mass Spectrometry.

2010 - Study ~ Effect of (-)-Delta(9)-tetrahydrocannabinoid on the hepatic redox state of mice.

2010 - Study ~ Exposure to a high-fat diet decreases sensitivity to Δ9-tetrahydrocannabinol-induced motor effects in female rats.

2010 - Study ~ Impact of cannabidiol on the acute memory and psychotomimetic effects of smoked cannabis: naturalistic study.

2010 - Study ~ The effects of Delta-tetrahydrocannabinol and cannabidiol alone and in combination on damage, inflammation and in vitro motility disturbances in rat colitis.

2010 - Study ~ Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain.

2010 - Study ~ Opposite Effects of Δ-9-Tetrahydrocannabinol and Cannabidiol on Human Brain Function and Psychopathology.

2010 - Study ~ Oral Delta 9-tetrahydrocannabinol improved refractory Gilles de la Tourette syndrome in an adolescent by increasing intracortical inhibition: a case report.

2010 - Study ~ Pharmacological evaluation of the natural constituent of Cannabis sativa, cannabichromene and its modulation by Δ9-tetrahydrocannabinol.

2010 - Study ~ Regulation of nausea and vomiting by cannabinoids.

2010 - Study ~ Smoked cannabis for chronic neuropathic pain: a randomized controlled trial.

2010 - Study ~ THC Prevents MDMA Neurotoxicity in Mice.

2010 - Study ~ The dual effects of delta(9)-tetrahydrocannabinol on cholangiocarcinoma cells: anti-invasion activity at low concentration and apoptosis induction at high concentration.

2010 - Study ~ Therapeutical use of the cannabinoids in psychiatry.

2010 - Study ~ Tocolytic Effect of Δ9-Tetrahydrocannabinol in Mice Model of Lipopolysaccharide—Induced Preterm Delivery: Role of Nitric Oxide.

2010 - Patent ~ Anti-tumoural effects of cannabinoid combinations - Patent TW201002315 (A) ― 2010-01-16.

2010 - News ~ Key ingredient staves off marijuana memory loss.

2010 - News ~ Marijuana May Extend Life Expectancy Of Lou Gehrig's Disease Patients, Study Says.

2010 - News ~ Science: Cannabidiol enhances the anti-cancer effects of THC on human brain cancer cells.

2010 - News ~ Science: Cannabis effective in the treatment of TOURETTE Syndrome and attention deficit hyperactivity disorder (ADHD).

2010 - News ~ THC Keeps Monkeys Alive in AIDS Research Model.

2011 - Study ~ Δ(9)-THC and WIN55,212-2 affect brain tissue levels of excitatory amino acids in a phenotype-, compound-, dose-, and region-specific manner.

2011 - Study ~ Cannabidiol potentiates Δ(9)-tetrahydrocannabinol (THC) behavioural effects and alters THC pharmacokinetics during acute and chronic treatment in adolescent rats.

2011 - Study ~ Cannabinoid Neuroimmune Modulation of SIV Disease.

2011 - Study ~ Combined effects of THC and caffeine on working memory in rats.

2011 - Study ~ Delta-9-tetrahydrocannabinol may palliate altered chemosensory perception in cancer patients: results of a randomized, double-blind, placebo-controlled pilot trial.

2011 - Study ~ Differential transcriptional profiles mediated by exposure to the cannabinoids cannabidiol and Δ(9) -tetrahydrocannabinol in BV-2 microglial cells.

2011 - Study ~ Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes.

2011 - Study ~ Effects of synthetic cannabinoids on electroencephalogram power spectra in rats.

2011 - Study ~ Evaluation of the Cyclooxygenase Inhibiting Effects of Six Major Cannabinoids Isolated from Cannabis sativa.

2011 - Study ~ Heterogeneity in the composition of marijuana seized in California.

2011 - Study Influence of agroclimatic conditions on content of main cannabinoids in industrial hemp (Cannabis sativa L.).

2011 - Study ~ Modulation of Auditory and Visual Processing by Delta-9-Tetrahydrocannabinol and Cannabidiol: an fMRI Study.

2011 - Study ~ Plasma cannabinoid pharmacokinetics following controlled oral delta9-tetrahydrocannabinol and oromucosal cannabis extract administration.

2011 - Study ~ Pharmacokinetics of a combination of Δ9-tetrahydro-cannabinol and celecoxib in a porcine model of hemorrhagic shock.

2011 - Study Pre- and post-conditioning treatment with an ultra-low dose of Δ9-tetrahydrocannabinol (THC) protects against pentylenetetrazole (PTZ)-induced cognitive damage.

2011 - Study ~ Prospects for cannabinoid therapies in basal ganglia disorders.

2011 - Study ~ Sex Differences in Cannabinoid 1 vs. Cannabinoid 2 Receptor-Selective Antagonism of Antinociception Produced by Δ9-Tetrahydrocannabinol and CP55,940 in the Rat.

2011 - Study ~ Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects.

2011 - Study Targeting cannabinoid receptors as a novel approach in the treatment of graft-versus-host disease: Evidence from an experimental murine model.

2011 - Study ~ THC and CBD oromucosal spray (Sativex®) in the management of spasticity associated with multiple sclerosis.

2011 - Study ~ The fatty acid amide hydrolase inhibitor URB 597: interactions with anandamide in rhesus monkeys.

2011 - Study ~ Tolerance to chronic delta-9-tetrahydrocannabinol (Δ⁹-THC) in rhesus macaques infected with simian immunodeficiency virus.

2011 - Patent ~ US Patent Application 20110257256 - CANNABINOIDS FOR USE IN TREATING OR PREVENTING COGNITIVE IMPAIRMENT AND DEMENTIA.

2011 - News ~ Another Study Confirms Anti-Cancer Effects of THC and CBD.

2011 - News ~ Ingredient in cannabis restores taste for cancer patients.

2011 - News Marijuana Compound Treats Multiple Health Issues.

2012 - Study ~ Δ(9) -THC exerts a direct neuroprotective effect in a human cell culture model of Parkinson's disease.

2012 - Study ~ A critical review of the antipsychotic effects of Cannabidiol: 30 years of a translational investigation.

2012 - Study ~ Acute effects of a single, oral dose of d9-tetrahydrocannabinol (THC) and cannabidiol (CBD) administration in healthy volunteers.

2012 - Study ~ Bimodal Control of Fear-Coping Strategies by CB1 Cannabinoid Receptors.

2012 - Study ~ Cannabidiol and clozapine reverse MK-801-induced deficits in social interaction and hyperactivity in Sprague-Dawley rats.

2012 - Study ~ Cannabinoid facilitation of fear extinction memory recall in humans.

2012 -Study ~ Cannabidiol for the treatment of cannabis withdrawal syndrome: a case report

2012 - Study ~ Cannabinoid Receptor Activity In The Tumour Necrosis Factor (tnf)−α-Induced Increased Contractility Of The Guinea-Pig Isolated Trachea.

2012 - Study ~ Cannabis derivatives therapy for a seronegative stiff-person syndrome: a case report.

2012 - Study ~ Effects of cannabinoids Δ(9)-tetrahydrocannabinol, Δ(9)-tetrahydrocannabinolic acid and cannabidiol in MPP(+) affected murine mesencephalic cultures.

2012 - Study ~ Effect of delta-9-tetrahydrocannabinol on behavioral despair and on presynaptic and postsynaptic serotonergic transmission.

2012 - Study ~ Effect of ion pairing on in vitro transcorneal permeability of a Δ(9) -tetrahydrocannabinol prodrug: potential in glaucoma therapy.

2012 - Study ~ Heat Exposure of Cannabis sativa Extracts Affects the Pharmacokinetic and Metabolic Profile in Healthy Male Subjects.

2012 - Study ~ Multiple Sclerosis and Extract of Cannabis: results of the MUSEC trial.

2012 - Study ~ Rimonabant eliminates responsiveness to workload changes in a time-constrained food-reinforced progressive ratio procedure in rats.

2012 - Study ~ Sex Differences in Cannabinoid 1 vs. Cannabinoid 2 Receptor-Selective Antagonism of Antinociception Produced by Δ9-Tetrahydrocannabinol and CP55,940 in the Rat.

2012 - Study ~ Single-dose Pharmacokinetics and Tolerability of Oral Delta-9-Tetrahydrocannabinol in Patients with Amyotrophic Lateral Sclerosis.

2012 - Study The cannabinoid receptor agonist THC attenuates weight loss in a rodent model of activity-based anorexia.

2012 - Patent ~ NANOENCAPSULATED DELTA-9-TETRAHYDROCANNABINOL - Patent US2012052119 (A1) ― 2012-03-01

2012 - News ~ Researchers study neuroprotective properties in cannabis.

2012 - News ~ Simple Method: Isolating & Extracting INDIVIDUAL Cannabinoids... from BadKittySmiles.

 2013 - Study ~ A new multiple sclerosis spasticity treatment option: effect in everyday clinical practice and cost-effectiveness in Germany.

2013 - Study ~ Cannabidiol as potential anticancer drug

2013 - Study ~ Cannabidiol enhances consolidation of explicit fear extinction in humans.

2013 - Study ~ COX-2 and PPAR-γ Confer Cannabidiol-Induced Apoptosis of Human Lung Cancer Cells.

2013 - Study ~ Effects of acute systemic administration of cannabidiol on sleep-wake cycle in rats.

2013 - Study ~ Endocannabinoid system modulator use in everyday clinical practice in the UK and Spain.

2013 - Study ~ Is the cardiovascular system a therapeutic target for cannabidiol?

2013 - Study ~ Local delivery of cannabinoid-loaded microparticles inhibits tumor growth in a murine xenograft model of glioblastoma multiforme.

2013 - Study ~ Non-THC cannabinoids inhibit prostate carcinoma growth in vitro and in vivo: pro-apoptotic effects and underlying mechanisms.

2013 - Study ~ The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system.
2013 - Study ~ Towards the use of non-psychoactive cannabinoids for prostate cancer