The discovery of many cannabis compounds has led to the further discovery of an important neurotransmitter system called the endocannabinoid system or ECS
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(THC), also known as delta-9-tetrahydrocannabinol, is the principal psychoactive constituent of the cannabis plant, and first isolated in 1964 by Israeli scientists Raphael Mechoulam, Yechiel Gaoni and colleagues at the Hebrew University of Jerusalem.

Difference between

Cannabis indica and Cannabis sativa

THC/ TETRAHYDROCANNABINOL HARDCOVER BOOKS

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THC/ TETRAHYDROCANNABINOL & Cannabis studies completed

Updated - News ~ Phytocannabinoids.

Updated - Transcript ~ Tetrahydrocannabinol- an interview with Akshat Rathi.

1946 - Study ~ Studies on the pharmacology and acute toxicity of compounds with marijuana activity.

1964 - 1st page Study ~ Isolation, Structure, and Partial Synthesis of an Active Constituent of Hashish.

1970 - Study ~ Chemical basis of hashish activity.

1971 - Study ~ Activity of Dgr8-and Dgr9-Tetrahydrocannabinol and Related Compounds in the Mouse.

1971 - Study ~ Some actions of delta-1 tetrahydrocannabinol and cannabidiol at cholinergic junctions.

1972 - Study ~ A metabolic interaction in vivo between cannabidiol and Δ1-tetrahydrocannabinol.

1972 - Study ~ Water-soluble derivatives of 1 -tetrahydrocannabinol.

1973 - Study ~ Effect of Biogenic Amines and Cannabinoids on Bacterial Chemotaxis.

1974 - Study ~ Acute effects of smoked marijuana and oral delta9-tetrahydrocannabinol on specific airway conductance in asthmatic subjects.

1974 - Study ~ A pilot study of orally administered Δ1-trans-tetrahydrocannabinol in the management of patients undergoing radiotherapy for carcinoma of the bronchus.

1974 - Study ~ Effects of marihuana in laboratory animals and in man.

1974 - Study ~ Smoked marijuana and oral delta-9-THC on specific airway conductance in asthmatic subjects.

1975 - Study ~ Absence of interaction between delta9-tetrahydrocannabinol (delta-THC) and cannabidiol (CBD) in aggression, muscle control and body temperature experiments in mice.

1975 - Study ~ Analgesic effect of delta-9-tetrahydrocannabinol.

1975 - Study ~ Antiepileptic and prophylactic effects of tetrahydrocannabinols in amygdaloid kindled cats.

1975 - Study ~ Effects of smoked marijuana in experimentally induced asthma.

1975 - Study ~ Interactions in man of delta-9-tetrahydrocannabinol. II. Cannabinol and cannabidiol.

1975 - Study ~ Intravenous delta9-Tetrahydrocannabinol: Effects of ventilatory control and cardiovascular dynamics.

1975 - Study ~ The analgesic properties of delta-9-tetrahydrocannabinol and codeine.

1975 - Study ~ The influence of delta9-tetrahydrocannabinol, cannabinol and cannabidiol on tissue oxygen consumption.

1976 - Study ~ Antibacterial activity of delta9-tetrahydrocannabinol and cannabidiol.

1976 - Study ~ Anticonvulsant activity of delta9-tetrahydrocannabinol compared with three other drugs.

1976 - Study ~ Bronchodilator effect of delta1-tetrahydrocannabinol administered by aerosol of asthmatic patients.

1977 - Study ~ Bronchial effects of aerosolized delta 9-tetrahydrocannabinol in healthy and asthmatic subjects.

1977 - Study ~ In vivo effects of cannabinoids on macromolecular biosynthesis in Lewis lung carcinomas.

1979 - Study ~ Delta-9-Tetrahydrocannibinol as an Antiemetic in Cancer Patients Receiving High-Dose Methotrexate.

1980 - Study ~ Marihuana as a therapeutic agent for muscle spasm or spasticity.

1980 - Study ~ Plasma delta-9-tetrahydrocannabinol concentrations and clinical effects after oral and intravenous administration and smoking.

1981 - Study ~ Activity of cannabis in relation to its delta'-trans-tetrahydro-cannabinol content.

1981 - Study ~ Sedative activity of cannabis in relation to its delta'-trans-tetrahydrocannabinol and cannabidiol content.

1981 - Study ~ The cardiovascular and autonomic effects of repeated administration of delta-9-tetrahydrocannabinol to rhesus monkeys.

1981 - Study ~ The seed and the soil: effect of dosage, personality and starting state on the response to delta 9 tetrahydrocannabinol in man.

1982 - Study ~ Comparison of effects of marihuana cigarettes of three different potencies.

1982 - Study ~ Ocular Effects of Topical Administration of {Delta}9-Tetrahydrocannabinol in Man.

1983 - Study ~ Allergenic properties of naturally occurring cannabinoids.

1983 - Study ~ Multiple-Drop Study of Topically Applied 1% {Delta}9-Tetrahydrocannabinol in Human Eyes.

1983 - Study ~ Neurobehavioral actions of cannabichromene and interactions with delta 9-tetrahydrocannabinol.

1983 - Study ~ Respiratory and cardiovascular depressant effects of nabilone, N-methyllevonantradol and delta 9-tetrahydrocannabinol in anesthetized cats.

1984 - Study ~ Acute Effects of Natural and Synthetic Cannabis Compounds on Prolactin Levels in Human Males.

1984- Study ~ Inhibition of neuroblastoma adenylate cyclase by cannabinoid and nantradol compounds.

1984 - Study ~ Intraocular pressure, ocular toxicity and neurotoxicity after administration of delta 9-tetrahydrocannabinol or cannabichromene.

1984 - Study ~ Ocular hypotension, ocular toxicity, and neurotoxicity in response to marihuana extract and cannabidiol.

1985- Study ~ Antiemetic efficacy of levonantradol compared to delta-9-tetrahydrocannabinol for chemotherapy-induced nausea and vomiting.

1985- Study ~ The quasi-morphine withdrawal syndrome: effect of cannabinol, cannabidiol and tetrahydrocannabinol.

1986- Study ~ The effect of delta-9-THC on human spasticity.

1987- Study ~ UV-B RADIATION EFFECTS ON PHOTOSYNTHESIS, GROWTH and CANNABINOID PRODUCTION OF TWO Cannabis sativa CHEMOTYPES.

1988- Study ~ Oral vs. Inhaled Cannabinoids for Nausea/Vomiting from Cancer Chemotherapy.

1989- Study ~ The inhibitory effects of cannabinoids, the active constituents of Cannabis sativa L. on human and rabbit platelet aggregation.

1990- Study ~ A comparison of the ocular and central effects of delta 9-tetrahydrocannabinol and cannabigerol.

1990- Study ~ Delta-9-tetrahydrocannabinol shows antispastic and analgesic effects in a single case double-blind trial.

1990- Study ~ Marijuana Smoking: Factors That Influence the Bioavailability of Tetrahydrocannabinol.

1991- Study ~ Chronic Exposure to Delta 9-tetrahydrocannabinol Fails to Irreversibly Alter Brain Cannabinoid Receptors.

1992- Study ~ Cannabinoid receptor agonists inhibit Ca current in NG108-15 neuroblastoma cells via a pertussis toxin-sensitive mechanism.

1993- Study ~ Cross-tolerance between delta-9-tetrahydrocannabinol and the cannabimimetic agents, CP 55,940, WIN 55,212-2 and anandamide.

1994- Study ~ Effects of delta 9-THC on marijuana smoking, dose choice, and verbal report of drug liking.

1994- Study ~ Interactions between delta 9-tetrahydrocannabinol and kappa opioids in mice.

1995- Study ~ Anandamide and delta 9-THC dilation of cerebral arterioles is blocked by indomethacin.

1995- Study ~ Cannabinoid precipitated withdrawal by the selective cannabinoid receptor antagonist, SR 141716A.

1996 - Study ~ Genetic differences in delta 9-tetrahydrocannabinol-induced facilitation of brain stimulation reward as measured by a rate-frequency curve-shift electrical brain stimulation paradigm in three different rat strains.

1996- Study ~ NTP Technical Report on the Toxicology and Carcinogenesis Studies of 1-Trans-Delta9-Tetrahyrdocannabinol (CAS No. 1972-08-3) in F344/N Rats and B6C3F1 Mice (Gavage Studies).

1996 - Study ~ The effect of orally and rectally administered delta-9-tetrahydrocannabinol on spasticity : a pilot study with 2 patients.

1996 - Study ~ Toxicity and Carcinogenicity of {Delta}9-Tetrahydrocannabinol in Fischer Rats and B6C3F1 Mice.

1997 - Study ~ Immunochemical localization of tetrahydrocannabinol (THC) in cryofixed glandular trichomes of Cannabis (Cannabaceae).

1997 - Study ~ The perceived effects of smoked cannabis on patients with multiple sclerosis.

1997 - News ~ Study: THC Not Cancer-Causing.

1998 - Study ~ Cannabidiol and (−)Δ9-tetrahydrocannabinol are neuroprotective antioxidants.

1998 - Study ~ Cerebellar activity and disturbed time sense after THC.

1999 - Study ~ Cannabis and cannabinoids: pharmacology and rationale for clinical use.

1999 - Study ~ Cannabis: Discrimination of "Internal Bliss"?

1999 - Letter ~ Treatment of Tourette's Syndrome With Delta-9-Tetrahydrocannabinol.

2000 - Study ~ Advantages of polypharmaceutical herbal cannabis compared to single ingredient, synthetic tetrahydrocannabinol.

2000 - Study ~ Anti-tumoral action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation.

2000 - Study ~ Cannabinoids in clinical practice.

2000 - Study ~ Cannabinoids might reduce spasticity in multiple sclerosis.

2000 - Study ~ Endogenous cannabinoids and appetite.

2000 - Study ~ GC-MS analysis of the total delta9-THC content of both drug- and fiber-type cannabis seeds.

2000 - Study ~ Variations of D9-THC content in single plants of hemp varieties.

2001 - Study ~ Clinical investigation of delta-9-tetrahydrocannabinol (THC) as an alternative therapy for overactive bladders in spinal cord injury (SCI) patients.

2001 - Study ~ Delta(9)-tetrahydrocannabinol and synthetic cannabinoids prevent emesis produced by the cannabinoid CB(1) receptor antagonist/inverse agonist SR 141716A.

2001 - Study ~ Neuroprotection by Delta 9-Tetrahydrocannabinol, the Main Active Compound in Marijuana, against Ouabain-Induced In Vivo Excitotoxicity.

2001 - Study ~ Tetrahydrocannabinol for treatment of chronic pain.

2002 - Study ~ Cannabinoids and multiple sclerosis.

2002 - Study ~ Cannabinoids in the treatment of pain and spasticity in multiple sclerosis.

2002 - Study ~ Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease.

2002 - Study ~ The potent emetogenic effects of the endocannabinoid, 2-AG (2-arachidonoylglycerol) are blocked by delta(9)-tetrahydrocannabinol and other cannnabinoids.

2003 - Study ~ Cannabinoid CB2 receptor activation reduces mouse myocardial ischemia-reperfusion injury: involvement of cytokine/chemokines and PMN.

2003 - Study ~ Cannabinoid influences on palatability: microstructural analysis of sucrose drinking after delta(9)-tetrahydrocannabinol, anandamide, 2-arachidonoyl glycerol and SR141716.

2003 - Study ~ Cannabinoids: Potential Anticancer Agents.

2003 - Study ~ Cannabis and the brain.

2003 - News ~ Cannabis can help MS sufferers.

2003 - Study ~ Cannabis use for chronic non-cancer pain: results of a prospective survey.

2003 - Study ~ Delta 9-tetrahydrocannabinol (THC) is effective in the treatment of tics in Tourette syndrome: a 6-week randomized trial.

2003 - Study ~ Effects of THC on Behavioral Measures of Impulsivity in Humans.

2003 - Study ~ Inhibition of tumor angiogenesis by cannabinoids.

2003 - Study ~ The Endogenous Cannabinoid System Regulates Seizure Frequency and Duration in a Model of Temporal Lobe Epilepsy.

2003 - Study ~ The treatment of spasticity with D9-THC) in patients with spinal cord injury.

2003 - Study ~ Treatment of Tourette Syndrome with Delta-9-Tetrahydrocannabinol (Delta9-THC): No Influence on Neuropsychological Performance.

2004 - Study ~ [123I] AM281 single-photon emission computed tomography imaging of central cannabinoid CB1 receptors before and after Delta9-tetrahydrocannabinol therapy and whole-body scanning for assessment of radiation dose in tourette patients.

2004 - Study ~ Cannabinoids: Defending the Epileptic Brain.

2004 - Study ~ Differential Effects of THC or CBD-rich Cannabis Extracts on Working Memory in Rats.

2004 - Study ~ Effect of Delta-9-tetrahydrocannabinol and cannabidiol on nocturnal sleep and early-morning behavior in young adults.

2004 - Study ~ Initial experiences with medicinal extracts of cannabis for chronic pain: Results from 34 ‘N of 1’ studies.

2004 - Study ~ The good and the bad effects of (−) trans-delta-9-tetrahydrocannabinol (Δ9-THC) on humans.

2004 - Study ~ Very low doses of delta 8-THC increase food consumption and alter neurotransmitter levels following weight loss.

2004 - News ~ THC in marijuana may block the spread of forms of cancer causing herpes viruses.

2004 - News ~ Cannabis truly helps multiple sclerosis sufferers. (may need registration)

2004 - News ~ Marijuana-like compounds may aid array of debiliating conditions ranging from Parkinson's to pain.

2005 - Study ~ Low dose oral cannabinoid therapy reduces progression of atherosclerosis in mice.

2005 - Study ~ Protective effects of Δ9-tetrahydrocannabinol against N-methyl-D-aspartate-induced AF5 cell death.

2005 - Study ~ Synergistic Interactions between Cannabinoids and Environmental Stress in the Activation of the Central Amygdala.

2005 - Study ~ The effects of Δ9-tetrahydrocannabinol in rat mesenteric vasculature, and its interactions with the endocannabinoid anandamide.

2005 - News ~ Cannabis may help keep arteries clear.

2005 - News ~ Cannabis Spray for Bipolar.

2005 - News ~ Chemicals in Cannabis may help mentally ill.

2005 - News ~ Medical marijuana: study shows that THC slows atherosclerosis.

2005 - News ~ New Synthetic Delta-9-THC Inhaler Offers Safe, Rapid Delivery , Phase I Study.

2005 - News ~ Science: THC slows development of atherosclerosis in animal study.

2005 - News ~ THC effective in appetite and weight loss in severe lung disease (COPD).

2006 - Study ~ Δ9-Tetrahydrocannabinol-Induced Apoptosis in Jurkat Leukemia T Cells Is Regulated by Translocation of Bad to Mitochondria.

2006 - Study ~ An Experimental Study of Catechol-O-Methyltransferase Val(158)Met Moderation of Delta-9-Tetrahydrocannabinol-Induced Effects on Psychosis and Cognition.

2006 - Study ~ A pilot clinical study of Delta(9)-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme.

2006 - Study ~ A tale of two cannabinoids:The therapeutic rationale for combining tetrahydrocannabinol and cannabidiol.

2006 - Study ~ Cannabinoids and the Endocannabinoid System.

2006 - Study ~ Comparison of orally administered cannabis extract and delta-9-tetrahydrocannabinol in treating patients with cancer-related anorexia-cachexia syndrome: a multicenter, phase III, randomized, double-blind, placebo-controlled clinical trial from the Cannabis-In-Cachexia-Study-Group.

2006 - Study ~ Delta-9-THC based monotherapy in fibromyalgia patients on experimentally induced pain, axon reflex flare, and pain relief.

2006 - Study ~ Delta}9-Tetrahydrocannabinol Inhibits Cell Cycle Progression in Human Breast Cancer Cells through Cdc2 Regulation.

2006 - Study ~ Delta(9)-Tetrahydrocannabinol protects hippocampal neurons from excitotoxicity.

2006 - Study ~ Differential effects of cannabis extracts and pure plant cannabinoids on hippocampal neurones and glia.

2006 - Study ~ Further Characterization of the Time-Dependent Vascular Effects of Δ9-Tetrahydrocannabinol.

2006 - Study ~ The Cannabinoid Cb1 Receptor Antagonist Rimonabant Attenuates the Hypotensive Effect of Smoked Marijuana in Male Smokers.

2006 - Study ~ Marijuana's Active Ingredient Shown to Inhibit Primary Marker of Alzheimer's Disease.

2006 - Study ~ Methods evaluating cannabinoid and endocannabinoid effects on gastrointestinal functions.

2006 - Study ~ The effects of cannabinoids on P-glycoprotein transport and expression in multidrug resistant cells.

2006 - Study ~ The treatment of spasticity with Delta(9)-tetrahydrocannabinol in persons with spinal cord injury.

2006 - News ~ Cannabis destroys cancer cells.

2006 - News ~ THC and prochlorperazine effective in reducing vomiting in women following breast surgery.

2006 - News ~ THC inhibits primary marker of Alzheimer's disease.

2007 - Study ~ Δ9-Tetrahydrocannabinol (THC) and AM 404 protect against cerebral ischaemia in gerbils through a mechanism involving cannabinoid and opioid receptors.

2007 - Study ~ Anandamide and Delta9-tetrahydrocannabinol directly inhibit cells of the immune system via CB2 receptors.

2007 - Study ~ CB2 receptors in the brain: role in central immune function.

2007 - Study ~ Cross-sensitization and cross-tolerance between exogenous cannabinoid antinociception and endocannabinoid-mediated stress-induced analgesia.

2007 - Study ~ Delta(9)-tetrahydrocannabinol (Delta(9)-THC) prevents cerebral infarction via hypothalamic-independent hypothermia.

2007 - Study ~ Effects of a Selective Cannabinoid Agonist and Antagonist on Body Temperature in Rats.

2007 - Study ~ Low dose combination of morphine and Δ9-tetrahydrocannabinol circumvents antinociceptive tolerance and apparent desensitization of receptors.

2007 - Study ~ Medicinal chemistry endeavors around the phytocannabinoids.
2007 - Study ~ On the pharmacological properties of Delta9-tetrahydrocannabinol.

2007 - Study ~ Opioid Antagonism of Cannabinoid Effects: Differences between Marijuana Smokers and Nonmarijuana Smokers.

2007 - Study ~ Repeated Treatment with Cannabidiol but Not Delta9-tetrahydrocannabinol Has a Neuroprotective Effect Without the Development of Tolerance.

2007 - Study ~ Symptomatic treatment of multiple sclerosis using cannabinoids: recent advances.

2007 - Study ~ Synergy between Delta(9)-tetrahydrocannabinol and morphine in the arthritic rat.

2007 - Study ~ THC improves appetite and reverses weight loss in AIDS patients.

2007 - Study ~ The antinociceptive effect of Delta9-tetrahydrocannabinol in the arthritic rat involves the CB(2) cannabinoid receptor.
2007 - Study ~ The cannabinoid delta(9)-tetrahydrocannabinol inhibits RAS-MAPK and PI3K-AKT survival signalling and induces BAD-mediated apoptosis in colorectal cancer cells.

 2007 - Study ~ The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin.

 2007 - Study ~ The psychoactive plant cannabinoid, Delta9-tetrahydrocannabinol, is antagonized by Delta8- and Delta9-tetrahydrocannabivarin in mice in vivo.

2007 - News ~ Cannabis can reduce Allergic Skin Reactions, latest research shows.

2007 - News ~ Pot's Active Ingredient Halts Lung Cancer Growth, Study Says.

2008 - Study ~ Δ9-Tetrahydrocannabinol Content of Commercially Available Hemp Products.

2008 - Study ~ Antibacterial cannabinoids from Cannabis sativa: a structure-activity study.

2008 - Study ~ Attenuation of Experimental Autoimmune Hepatitis by Exogenous and Endogenous Cannabinoids: Involvement of Regulatory T Cells.

2008 - Study ~ Cannabinoids in the management of difficult to treat pain.

2008 - Study ~ Cannabinoid receptors in acute and chronic complications of atherosclerosis.

2008 - Study ~ Delta-9-tetrahydrocannabinol pharmacokinetics.

2008 - Study ~ Divergent effects of cannabidiol on the discriminative stimulus and place conditioning effects of Δ9-tetrahydrocannabinol.

2008 - Study ~ Effect of intrapulmonary tetrahydrocannabinol administration in humans.

2008 - Study ~ High concentrations of cannabinoids activate apoptosis in human U373MG glioma cells.

2008 - Study ~ The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin.

2008 - News ~ CSI: fingerprinting and drug detection in one.

2008 - News ~ Science: THC reduces reflux of acid from the stomach.

2009 - Study ~ Actions of delta-9-tetrahydrocannabinol in cannabis.

2009 - Study ~ Cannabidiol reverses the reduction in social interaction produced by low dose Delta(9)-tetrahydrocannabinol in rats.

2009 - Study ~ Cannabinoids Δ9-Tetrahydrocannabinol and Cannabidiol Differentially Inhibit the Lipopolysaccharide-activated NF-κB and Interferon-β/STAT Proinflammatory Pathways in BV-2 Microglial Cells.

2009 - Study ~ Cannabinoids, Endocannabinoids, and Related Analogs in Inflammation.

2009 - Study ~ Cannabinoid action induces autophagymediated cell death through stimulation of ER stress in human glioma cells.

2009 - Study ~ Cannabinoid Receptor 1 Binding Activity and Quantitative Analysis of Cannabis sativa L. Smoke and Vapor.

2009 - Study ~ Cannabinoid receptor 1 is a potential drug target for treatment of translocation-positive rhabdomyosarcoma.

2009 - Study ~ Delta 9-tetrahydrocannabinol induces dopamine release in the human striatum.

2009 - Study ~ Evaluation of Prevalent Phytocannabinoids in the Acetic Acid Model of Visceral Nociception.

2009 - Study ~ Hydroxylation and Further Oxidation of Δ9-Tetrahydrocannabinol by Alkane-Degrading Bacteria.

2009 - Study ~ Modulation of effective connectivity during emotional processing by Delta9-tetrahydrocannabinol and cannabidiol.

2009 - Study ~ Neurocognitive performance during acute THC intoxication in heavy and occasional cannabis users.

2009 - Study ~ Opposite Effects of Delta-9-Tetrahydrocannabinol and Cannabidiol on Human Brain Function and Psychopathology.

2009 - Study ~ Tetrahydrocannabinol (Delta 9-THC) Treatment in Chronic Central Neuropathic Pain and Fibromyalgia Patients: Results of a Multicenter Survey.

2009 - Study ~ Synthetic and plant-derived cannabinoid receptor antagonists show hypophagic properties in fasted and non-fasted mice.

2009 - Study ~ TRB3 links ER stress to autophagy in cannabinoid anti-tumoral action.

2009 - News ~ Active cannabis chemicals halt prostate cancer cell growth.

2009 - News ~ Active Component Of Marijuana Has Anti-Cancer Effects, Study Suggests.

2009 - News ~ Marijuana Chemicals Ease MS Symptoms, Review Confirms.

2009 - News ~ THC initiates brain cancer cells to destroy themselves.

2010 - Study ~ A behavioural comparison of acute and chronic Delta9-tetrahydrocannabinol and cannabidiol in C57BL/6JArc mice.

2010 - Study ~ Antidepressant-like effect of Delta(9)-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L.

2010 - Study ~ Antitumorigenic Effects of Cannabinoids beyond Apoptosis.

2010 - Study ~ Cannabinoid receptor CB1 mediates baseline and activity-induced survival of new neurons in adult hippocampal neurogenesis.

2010 - Study ~ Cannabinoids Inhibit Cellular Respiration of Human Oral Cancer Cells.

2010 - Study ~ Chronic cannabinoid administration lowers viral replication in lymph nodes of SIV infected Rhesus macaques.

2010 - Study ~ Delta9-tetrahydrocannabinol is a full agonist at CB1 receptors on GABA neuron axon terminals in the hippocampus.

2010 - Study ~ Disposition of Cannabichromene, Cannabidiol, and Δ9-Tetrahydrocannabinol and its Metabolites in Mouse Brain following Marijuana Inhalation Determined by High-Performance Liquid Chromatography-Tandem Mass Spectrometry.

2010 - Study ~ Effect of (-)-Delta(9)-tetrahydrocannabinoid on the hepatic redox state of mice.

2010 - Study ~ Exposure to a high-fat diet decreases sensitivity to Δ9-tetrahydrocannabinol-induced motor effects in female rats.

2010 - Study ~ Impact of cannabidiol on the acute memory and psychotomimetic effects of smoked cannabis: naturalistic study.

2010 - Study ~ The effects of Delta-tetrahydrocannabinol and cannabidiol alone and in combination on damage, inflammation and in vitro motility disturbances in rat colitis.

2010 - Study ~ Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain.

2010 - Study ~ Opposite Effects of Δ-9-Tetrahydrocannabinol and Cannabidiol on Human Brain Function and Psychopathology.

2010 - Study ~ Oral Delta 9-tetrahydrocannabinol improved refractory Gilles de la Tourette syndrome in an adolescent by increasing intracortical inhibition: a case report.

2010 - Study ~ Pharmacological evaluation of the natural constituent of Cannabis sativa, cannabichromene and its modulation by Δ9-tetrahydrocannabinol.

2010 - Study ~ Regulation of nausea and vomiting by cannabinoids.

2010 - Study ~ Smoked cannabis for chronic neuropathic pain: a randomized controlled trial.

2010 - Study ~ THC Prevents MDMA Neurotoxicity in Mice.

2010 - Study ~ The dual effects of delta(9)-tetrahydrocannabinol on cholangiocarcinoma cells: anti-invasion activity at low concentration and apoptosis induction at high concentration.

2010 - Study ~ Therapeutical use of the cannabinoids in psychiatry.

2010 - Study ~ Tocolytic Effect of Δ9-Tetrahydrocannabinol in Mice Model of Lipopolysaccharide—Induced Preterm Delivery: Role of Nitric Oxide.

2010 - Patent ~ Anti-tumoural effects of cannabinoid combinations - Patent TW201002315 (A) ― 2010-01-16.

2010 - News ~ Key ingredient staves off marijuana memory loss.

2010 - News ~ Marijuana May Extend Life Expectancy Of Lou Gehrig's Disease Patients, Study Says.

2010 - News ~ Science: Cannabidiol enhances the anti-cancer effects of THC on human brain cancer cells.

2010 - News ~ Science: Cannabis effective in the treatment of TOURETTE Syndrome and attention deficit hyperactivity disorder (ADHD).

2010 - News ~ THC Keeps Monkeys Alive in AIDS Research Model.

2011 - Study ~ Δ(9)-THC and WIN55,212-2 affect brain tissue levels of excitatory amino acids in a phenotype-, compound-, dose-, and region-specific manner.

2011 - Study ~ Cannabidiol potentiates Δ(9)-tetrahydrocannabinol (THC) behavioural effects and alters THC pharmacokinetics during acute and chronic treatment in adolescent rats.

2011 - Study ~ Cannabinoid Neuroimmune Modulation of SIV Disease.

2011 - Study ~ Combined effects of THC and caffeine on working memory in rats.

2011 - Study ~ Delta-9-tetrahydrocannabinol may palliate altered chemosensory perception in cancer patients: results of a randomized, double-blind, placebo-controlled pilot trial.

2011 - Study ~ Differential transcriptional profiles mediated by exposure to the cannabinoids cannabidiol and Δ(9) -tetrahydrocannabinol in BV-2 microglial cells.

2011 - Study ~ Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes.

2011 - Study ~ Effects of synthetic cannabinoids on electroencephalogram power spectra in rats.

2011 - Study ~ Evaluation of the Cyclooxygenase Inhibiting Effects of Six Major Cannabinoids Isolated from Cannabis sativa.

2011 - Study ~ Heterogeneity in the composition of marijuana seized in California.

2011 - Study Influence of agroclimatic conditions on content of main cannabinoids in industrial hemp (Cannabis sativa L.).

2011 - Study ~ Modulation of Auditory and Visual Processing by Delta-9-Tetrahydrocannabinol and Cannabidiol: an fMRI Study.

2011 - Study ~ Plasma cannabinoid pharmacokinetics following controlled oral delta9-tetrahydrocannabinol and oromucosal cannabis extract administration.

2011 - Study ~ Pharmacokinetics of a combination of Δ9-tetrahydro-cannabinol and celecoxib in a porcine model of hemorrhagic shock.

2011 - Study Pre- and post-conditioning treatment with an ultra-low dose of Δ9-tetrahydrocannabinol (THC) protects against pentylenetetrazole (PTZ)-induced cognitive damage.

2011 - Study ~ Prospects for cannabinoid therapies in basal ganglia disorders.

2011 - Study ~ Sex Differences in Cannabinoid 1 vs. Cannabinoid 2 Receptor-Selective Antagonism of Antinociception Produced by Δ9-Tetrahydrocannabinol and CP55,940 in the Rat.

2011 - Study ~ Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects.

2011 - Study Targeting cannabinoid receptors as a novel approach in the treatment of graft-versus-host disease: Evidence from an experimental murine model.

2011 - Study ~ THC and CBD oromucosal spray (Sativex®) in the management of spasticity associated with multiple sclerosis.

2011 - Study ~ The fatty acid amide hydrolase inhibitor URB 597: interactions with anandamide in rhesus monkeys.

2011 - Study ~ Tolerance to chronic delta-9-tetrahydrocannabinol (Δ⁹-THC) in rhesus macaques infected with simian immunodeficiency virus.

2011 - Patent ~ US Patent Application 20110257256 - CANNABINOIDS FOR USE IN TREATING OR PREVENTING COGNITIVE IMPAIRMENT AND DEMENTIA.

2011 - News ~ Another Study Confirms Anti-Cancer Effects of THC and CBD.

2011 - News ~ Ingredient in cannabis restores taste for cancer patients.

2011 - News Marijuana Compound Treats Multiple Health Issues.

2012 - Study ~ Δ(9) -THC exerts a direct neuroprotective effect in a human cell culture model of Parkinson's disease.

2012 - Study ~ A critical review of the antipsychotic effects of Cannabidiol: 30 years of a translational investigation.

2012 - Study ~ Acute effects of a single, oral dose of d9-tetrahydrocannabinol (THC) and cannabidiol (CBD) administration in healthy volunteers.

2012 - Study ~ Bimodal Control of Fear-Coping Strategies by CB1 Cannabinoid Receptors.

2012 - Study ~ Cannabidiol and clozapine reverse MK-801-induced deficits in social interaction and hyperactivity in Sprague-Dawley rats.

2012 - Study ~ Cannabinoid facilitation of fear extinction memory recall in humans.

2012 -Study ~ Cannabidiol for the treatment of cannabis withdrawal syndrome: a case report

2012 - Study ~ Cannabinoid Receptor Activity In The Tumour Necrosis Factor (tnf)−α-Induced Increased Contractility Of The Guinea-Pig Isolated Trachea.

2012 - Study ~ Cannabis derivatives therapy for a seronegative stiff-person syndrome: a case report.

2012 - Study ~ Effects of cannabinoids Δ(9)-tetrahydrocannabinol, Δ(9)-tetrahydrocannabinolic acid and cannabidiol in MPP(+) affected murine mesencephalic cultures.

2012 - Study ~ Effect of delta-9-tetrahydrocannabinol on behavioral despair and on presynaptic and postsynaptic serotonergic transmission.

2012 - Study ~ Effect of ion pairing on in vitro transcorneal permeability of a Δ(9) -tetrahydrocannabinol prodrug: potential in glaucoma therapy.

2012 - Study ~ Heat Exposure of Cannabis sativa Extracts Affects the Pharmacokinetic and Metabolic Profile in Healthy Male Subjects.

2012 - Study ~ Multiple Sclerosis and Extract of Cannabis: results of the MUSEC trial.

2012 - Study ~ Rimonabant eliminates responsiveness to workload changes in a time-constrained food-reinforced progressive ratio procedure in rats.

2012 - Study ~ Sex Differences in Cannabinoid 1 vs. Cannabinoid 2 Receptor-Selective Antagonism of Antinociception Produced by Δ9-Tetrahydrocannabinol and CP55,940 in the Rat.

2012 - Study ~ Single-dose Pharmacokinetics and Tolerability of Oral Delta-9-Tetrahydrocannabinol in Patients with Amyotrophic Lateral Sclerosis.

2012 - Study The cannabinoid receptor agonist THC attenuates weight loss in a rodent model of activity-based anorexia.

2012 - Patent ~ NANOENCAPSULATED DELTA-9-TETRAHYDROCANNABINOL - Patent US2012052119 (A1) ― 2012-03-01

2012 - News ~ Researchers study neuroprotective properties in cannabis.

2012 - News ~ Simple Method: Isolating & Extracting INDIVIDUAL Cannabinoids... from BadKittySmiles.

 2013 - Study ~ A new multiple sclerosis spasticity treatment option: effect in everyday clinical practice and cost-effectiveness in Germany.

2013 - Study ~ Cannabidiol as potential anticancer drug

2013 - Study ~ Cannabidiol enhances consolidation of explicit fear extinction in humans.

2013 - Study ~ COX-2 and PPAR-γ Confer Cannabidiol-Induced Apoptosis of Human Lung Cancer Cells.

2013 - Study ~ Effects of acute systemic administration of cannabidiol on sleep-wake cycle in rats.

2013 - Study ~ Endocannabinoid system modulator use in everyday clinical practice in the UK and Spain.

2013 - Study ~ Is the cardiovascular system a therapeutic target for cannabidiol?

2013 - Study ~ Local delivery of cannabinoid-loaded microparticles inhibits tumor growth in a murine xenograft model of glioblastoma multiforme.

2013 - Study ~ Non-THC cannabinoids inhibit prostate carcinoma growth in vitro and in vivo: pro-apoptotic effects and underlying mechanisms.

2013 - Study ~ The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system.
2013 - Study ~ Towards the use of non-psychoactive cannabinoids for prostate cancer

THC/ TETRAHYDROCANNABINOL HARDCOVER BOOKS

THC (Tetrahydrocannabinol) Molecular Model KitModulation of hippocampal endocannabinoid plasticity by homer proteins and delta(9)-tetrahydrocannabinol.Interpretation of Delta9-tetrahydrocannabinol (THC), 11-hydroxy-THC (11-OH-THC) & 11-nor-9-carboxy-THC (THCCOOH) concentrations in blood and urine of frequent cannabis users.Tétrahydrocannabinol (French Edition)The  Psychopharmacology of Herbal Medicine: Plant Drugs That Alter Mind, Brain, and BehaviorCorrelation of @D^9-tetrahydrocannabinol concentrations determined by LC-MS-MS in oral fluid and plasma from impaired drivers and evaluation of the ... article from: Forensic Science International

 

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