NEURONS/ BRAIN CELLS & Cannabis studies completed




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A neuron is an electrically excitable cell that processes and transmits information through electrical and chemical signals

1990 - Study ~ Cannabinoid Receptor Localization in Brain

1994 - Letter ~ Formation and inactivation of endogenous cannabinoid anandamide in central neurons.

1995 - Study ~ Anandamide amidohydrolase activity in rat brain microsomes. Identification and partial characterization.

1995 - Study ~ The CB1 cannabinoid receptor antagonist SR 141716A affects A9 dopamine neuronal activity in the rat.

1996 - Study ~ Genetic differences in delta 9-tetrahydrocannabinol-induced facilitation of brain stimulation reward as measured by a rate-frequency curve-shift electrical brain stimulation paradigm in three different rat strains.

1998 - Study ~ Cannabinoid Receptor Agonists Protect Cultured Rat Hippocampal Neurons from Excitotoxicity

1998 - Study ~ Potent Effects of a Selective Cannabinoid Receptor Agonist on Some Guinea Pig Medial Vestibular Nucleus Neurons.

1998 - Study ~ Loss of Cannabinoid Receptor Binding and Messenger Rna Levels and Cannabinoid Agonist-stimulated [35s]guanylyl-5'o-(Thio)-triphosphate Binding in the Basal Ganglia of Aged Rats.

1999- Study ~ Expression of the cannabinoid receptor CB1 in distinct neuronal subpopulations in the adult mouse forebrain.

2000 - Study ~ Neuroprotective Antioxidants from Marijuana

2000 - Study ~ Endocannabinoids in the central nervous system--an overview.

2003 - Study ~ Neurons on cannabinoids: dead or alive?

2003 - Study ~ Role of Endogenous Cannabinoids in Synaptic Signaling

2003 - Study ~ Cannabis and the brain.

2003 - Study ~ Cannabinoid receptor type 1 modulates excitatory and inhibitory neurotransmission in mouse colon

2003 - Study ~ Post-ischemic Treatment with Cannabidiol Prevents Electroencephalographic Flattening, Hyperlocomotion and Neuronal Injury in Gerbils.

2003 - Study ~ Cannabinoid Modulation of Peripheral Autonomic and Sensory Neurotransmission.

2004 - Study ~ Cannabinoids and neuroinflammation

2004 - Study ~ Defective adult neurogenesis in CB1 cannabinoid receptor knockout mice.

2004 - News ~ Marijuana-Like Chemicals in the Brain Calm Neurons

2005 - Study ~ Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects

2005 - Study ~ Identification and functional characterization of brainstem cannabinoid CB2 receptors.

2005 - Study ~ The endocannabinoid system drives neural progenitor proliferation.

2005 - Study ~ Sex differences in the cannabinoid modulation of an A-type K+ current in neurons of the mammalian hypothalamus.

2005 - News ~ High-dose cannabis stimulates growth of brain cells in rats

2005 - News ~ Marijuana Promotes Neuron Growth

2005 - News Forum ~ Marijuana May Spur New Brain Cells

2005 - News ~ Good News For The Medical Marijuana Movement: Pot Proliferates Brain Cells And Boosts Mood

2005 - News ~ Marijuana May Grow Neurons in the Brain

2006 - Study ~ Non-psychoactive CB2 cannabinoid agonists stimulate neural progenitor proliferation

2006 - Study ~ Differential effect of cannabinoid agonists and endocannabinoids on histamine release from distinct regions of the rat brain.

2006 - Study ~ Differential effects of cannabis extracts and pure plant cannabinoids on hippocampal neurones and glia.

2006 - Study ~ Neuromodulatory functions of the endocannabinoid system.

2007 - Study ~ The synthetic cannabinoid HU210 induces spatial memory deficits and suppresses hippocampal firing rate in rats

2007 - Study ~ CB2 cannabinoid receptors promote mouse neural stem cell proliferation.

2007 - Study ~ The endocannabinoid system and neurogenesis in health and disease.

2008 - Study ~ The CB2 Cannabinoid Receptor Controls Myeloid Progenitor Trafficking:
INVOLVEMENT IN THE PATHOGENESIS OF AN ANIMAL MODEL OF MULTIPLE SCLEROSIS

2008 - Study ~ Design Logic of a Cannabinoid Receptor Signaling Network That Triggers Neurite Outgrowth

2008 - News ~ New brain cells implicated in machinery of cannabinoid signaling

2009 - Study ~ Delta 9-tetrahydrocannabinol induces dopamine release in the human striatum.

2009 - Study ~ Cannabinoid agonist WIN-55,212-2 partially restores neurogenesis in the aged rat brain

2009- Study ~ Endocannabinoid-mediated control of synaptic transmission.

2009 - Study ~ Cannabinoids attenuate the effects of aging upon neuroinflammation and neurogenesis

2009 - Study ~ Endocannabinoid signaling in neurotoxicity and neuroprotection.

2009 - Study ~ Effects of cannabidiol on amphetamine-induced oxidative stress generation in an animal model of mania

2009 - Study ~ Oleoylethanolamide exerts partial and dose-dependent neuroprotection of substantia nigra dopamine neurons.

2009 - Study ~ Cannabinoid receptors in brain: pharmacogenetics, neuropharmacology, neurotoxicology, and potential therapeutic applications.

2010- Study ~ Cyclooxygenase-2 Mediates Anandamide Metabolism in the Mouse Brain

2010 - Study ~ Cannabinoids Excite Circadian Clock Neurons

2010 - Study ~ Cannabinoid receptor CB1 mediates baseline and activity-induced survival of new neurons in adult hippocampal neurogenesis

2010 - Study ~ AAV vector-mediated overexpression of CB1 cannabinoid receptor in pyramidal neurons of the hippocampus protects against seizure-induced excitoxicity.

2010 - Study ~ Sex difference in cell proliferation in developing rat amygdala mediated by endocannabinoids has implications for social behavior.

2010 - Study ~ CB1 cannabinoid receptors increase neuronal precursor proliferation through AKT/glycogen synthase kinase-3beta/beta-catenin signaling.

2010- Study ~ Cannabidiol protects retinal neurons by preserving glutamine synthetase activity in diabetes.

2010 - Study ~ Regulatory Role of Cannabinoid Receptor 1 in Stress-Induced Excitotoxicity and Neuroinflammation

2010 - Study ~ Palmitoylethanolamide and other anandamide congeners. Proposed role in the diseased brain.

2010 - Study ~ Endocannabinoids Prevent β-Amyloid-mediated Lysosomal Destabilization in Cultured Neurons

2010 - Study ~ PP-014 Control of receptor expression in vagal afferent neurons by activation of cannabinoid 1 receptors

2010 - Study ~ Protective effects of the synthetic cannabinoids CP55,940 and JWH-015 on rat brain mitochondria upon paraquat exposure.

2010 - Study ~ Delta9-tetrahydrocannabinol is a full agonist at CB1 receptors on GABA neuron axon terminals in the hippocampus.

2010 - News ~ Chronic Low Doses of a Cannabinoid Causes New Brain Cell Formation

2011 - Study ~ Cannabidiol Reduces Aβ-Induced Neuroinflammation and Promotes Hippocampal Neurogenesis through PPARγ Involvement

2011 - Study ~ Sex difference in cell proliferation in developing rat amygdala mediated by endocannabinoids has implications for social behavior

2011 - Study ~ Dual inhibition of alpha/beta hydrolase domain 6 and fatty acid amide hydrolase increases endocannabinoid levels in neurons.

2011 - Study ~ Cannabinoid receptor agonist protects cultured dopaminergic neurons from the death by the proteasomal dysfunction

2011 - Study ~ Endocannabinoid signaling in the amygdala: anatomy, synaptic signaling, behavior, and adaptations to stress.

2011 - Study ~ The Dopamine and Cannabinoid Interaction in the Modulation of Emotions and Cognition: Assessing the Role of Cannabinoid CB1 Receptor in Neurons Expressing Dopamine D1 Receptors.

2011 - Study ~ History of cannabis use is not associated with alterations in striatal dopamine D2/D3 receptor availability.

2011- Study ~ The G protein-coupled cannabinoid-1 (CB(1)) receptor of mammalian brain: Inhibition by phthalate esters in vitro.

2011 - Study ~ α-Tocopherol and α-tocopheryl phosphate interact with the cannabinoid system in the rodent hippocampus.

2011 - Study ~ Effects of synthetic cannabinoids on electroencephalogram power spectra in rats.

2011 - Study ~ Pharmacological activation/inhibition of the cannabinoid system affects alcohol withdrawal-induced neuronal hypersensitivity to excitotoxic insults.

2011 - Study ~ CB2 Cannabinoid Receptors Promote Neural Progenitor Cell Proliferation via mTORC1 Signaling

2011 - Study ~ Nutritional omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions

2011 - Study ~ Δ(9)-THC and WIN55,212-2 affect brain tissue levels of excitatory amino acids in a phenotype-, compound-, dose-, and region-specific manner

2011 - Study ~ Cannabinoid Receptor Type 1 Protects Nigrostriatal Dopaminergic Neurons against MPTP Neurotoxicity by Inhibiting Microglial Activation

2011 - Study ~ Activation of Cannabinoid Type 2 Receptors Inhibits HIV-1 Envelope Glycoprotein gp120-Induced Synapse Loss

2011- News ~ A Brain Wrought Without Omega-3

2012 - Study ~ Role of CB1 cannabinoid receptors on GABAergic neurons in brain aging

2012 - Study ~ Type-1 Cannabinoid Receptor Signaling in Neuronal Development.

2012- Study ~ Endocannabinoids and the processing of value-related signals.

2012 - Study ~ Palmitoylethanolamide exerts neuroprotective effects in mixed neuroglial cultures and organotypic hippocampal slices via peroxisome proliferator-activated receptor-α.

2012- Study ~ Mitochondrial CB(1) receptors regulate neuronal energy metabolism.

2012 - Study ~ Effects of cannabinoids Δ(9)-tetrahydrocannabinol, Δ(9)-tetrahydrocannabinolic acid and cannabidiol in MPP(+) affected murine mesencephalic cultures.

2012 - Study ~ Cannabinoid modulation of midbrain urocortin 1 neurones during acute and chronic stress.

2012 - Study ~ Long-lasting potentiation of hippocampal synaptic transmission by direct cortical input is mediated via endocannabinoids

2012 - Study ~ Excitability of prefrontal cortical pyramidal neurons is modulated by activation of 98 intracellular type-2 cannabinoid receptors.