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DEPRESSION & Cannabis studies completed

Depression is a tough thing. There are more than 350 million people wVisit Seedsman Now!orldwide that suffer from depression. One of the saddest things to me about depression is the lack of effective medications that a person can take. Doctors almost always prescribe pharmaceuticals for depression, many of which have harmful side effects. Whenever you see a commercial on TV for a depression medication, the list of potential side effects is usually longer than the segment of the commercial dedicated to how well it works. I have seen many pharmaceutical commercials list ‘thoughts of suicide’ as one of the main potential side effects.

A study was recently released which found that marijuana can be an effective treatment for depression. Marijuana of course doesn’t cause the side effects that pharmaceuticals do. Per the Huffington Post:

2000 - Study ~ Anxiety with Depression Research Review.

2001 - Study ~ Therapeutic Aspects of Cannabis and Cannabinoids.

2004 - Study ~ Association between cannabis use and depression may not be causal, study says.

2005 - Study ~ Cannabinoids promote hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects.

2005 - Study ~ Antidepressant-like activity by blockade of anandamide hydrolysis.

2005 - Study ~ Depression in Parkinson's disease is related to a genetic polymorphism of the cannabinoid receptor gene (CNR1).

2005 - Study ~ Antidepressant-like Activity and Modulation of Brain Monoaminergic Transmission by Blockade of Anandamide Hydrolysis.

2005 - Study ~ Decreased Depression in Marijuana Users.

2005 - News ~ Depression: URB597 increases endocannabinoids in brain.

2005 - News ~ New Antidepressant Drug Increases 'Brain's Own Cannabis'.

2005 - News ~ Cannabis' Acts as Antidepressant.

2005 - News ~ Cannabis And Depression Research.

2005 - News ~ High-dose cannabis stimulates growth of brain cells in rats.

2005 - News ~ Good News For The Medical Marijuana Movement: Pot Proliferates Brain Cells And Boosts Mood.

2005 - News ~ Marijuana might cause new cell growth in the brain.

2005 - News ~ Surprising Brain Effects From Pot-Like Drug.

2006 - Study ~ Decreased depression in marijuana users.

2006 - Study ~ The synthetic cannabinoid nabilone improves pain and symptom management in cancer patients.

2006 - Study ~ Marijuana use and depression among adults: Testing for causal associations.

2006 - Study ~ Do patients use marijuana as an antidepressant?

2006 - Study ~ A possible role for the endocannabinoid system in the neurobiology of depression.

2007 - Study ~ Chronologically overlapping occurrences of nicotine-induced anxiety- and depression-related behavioral symptoms: effects of anxiolytic and cannabinoid drugs.

2007 - Study ~ Cannabinoids elicit antidepressant-like behavior and activate serotonergic neurons through the medial prefrontal cortex.

2007 - Study ~ Antidepressant-like activity of the fatty acid amide hydrolase inhibitor URB597 in a rat model of chronic mild stress.

2007 - Study ~ Dronabinol and marijuana in HIV-positive marijuana smokers: caloric intake, mood, and sleep.

2007 - News ~ Marijuana-Like Brain Chemicals Work As Antidepressant.

2007 - News ~ Marijuana chemical may treat depression.

2007 - News ~ Cannabis: Potent Anti-Depressant In Low Doses, Worsens Depression At High Doses.

2007 - News ~ Synthetic form of THC is an effective anti-depressant at low doses.

2007 - News ~ Rimonabant: safety issues.

2008 - Study ~ Treating depression with cannabinoids.

2008 - Study ~ Nicotine (NC)-induced "depressive" behavioral symptoms and effects of antidepressants including cannabinoids (CBs).

2008 - Study ~ Animal research highlights a therapeutic potential of cannabinoids for the treatment of depression.

2009 - Study ~ Circulating endocannabinoids and N-acyl ethanolamines are differentially regulated in major depression and following exposure to social stress.

2009 - Study ~ Impairments in Endocannabinoid Signaling and Depressive Illness.

2009 - Study ~ Protracted cannabinoid administration elicits antidepressant behavioral responses in rats: role of gender and noradrenergic transmission.

2009 - Study ~ Cannabis and suicide: longitudinal study.

2009 - News ~ Medical Marijuana and Major Depression.

2010 - Study ~ Antidepressant-like effect of delta9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L.

2010 - Study ~ Brain CB2 Receptors: Implications for Neuropsychiatric Disorders.

2010 - Study ~ Uni-Morbid and Co-Occurring Marijuana and Tobacco Use: Examination of Concurrent Associations with Negative Mood States.

2010 - Study ~ Genes differentially expressed in CB1 knockout mice: involvement in the depressive-like phenotype.

2010 - Study ~ Deficiency in Endocannabinoid Signaling in the Nucleus Accumbens Induced by Chronic Unpredictable Stress.

2010 - Study ~ Pharmacological exploitation of the endocannabinoid system: new perspectives for the treatment of depression and anxiety disorders?

2011 - Study ~ Gadolinium-HU-308-incorporated micelles.

2011 - Study ~ Nutritional omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions.

2011 - Study ~ Endocannabinoid system dysfunction in mood and related disorders.

2011 - Study ~ Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress.

2011 - Study ~ Cannabinoids and emotionality: a neuroanatomical perspective.

2011 - Study ~ Testing bidirectional effects between cannabis use and depressive symptoms: moderation by the serotonin transporter gene.

2011 - News ~ Deficiency of Dietary Omega-3 May Explain Depressive Behaviors.

2011 - News ~ A Brain Wrought Without Omega-3.

2011 - News ~ Omega-3 deficiency disrupts cannibinoid receptor function in brain.

2011 - News ~ Natural Herbs That Increase Serotonin.

2011 - News ~ Research provides new clues to understand link between deficits of AGPO-3, depression.

2012 - Study ~ High on Life? Medical Marijuana Laws and Suicide.

2012 - Study ~ Serum contents of endocannabinoids are correlated with blood pressure in depressed women.

2012 - Study ~ Cannabinoid Receptor Genotype Moderation of the Effects of Childhood Physical Abuse on Anhedonia and Depression.

2012 - Study ~ Effect of delta-9-tetrahydrocannabinol on behavioral despair and on presynaptic and postsynaptic serotonergic transmission.

2012 - Study ~ Nature Against Depression.

2012 - Study ~ Lower levels of cannabinoid 1 receptor mRNA in female eating disorder patients: Association with wrist cutting as impulsive self-injurious behavior.

2012 - Study ~ Expression pattern of the cannabinoid receptor genes in the frontal cortex of mood disorder patients and mice selectively bred for high and low fear.

2012 - Study ~ The combined effects of parental divorce and parental history of depression on cannabis use in young adults in France.

2012 - Study ~ Genetic variability in the endocannabinoid system and 12-week clinical response to citalopram treatment: the role of the CNR1, CNR2 and FAAH genes

2012 - Study ~ Opposing local effects of endocannabinoids on the activity of noradrenergic neurons and release of noradrenaline: relevance for their role in depression and in the actions of CB(1) receptor antagonists.

2012 - Study ~ Essential fatty acids and lipid mediators. Endocannabinoids

2012 - Study ~ Endocannabinoid system and mood disorders: Priming a target for new therapies.

2012 - News ~ Smoking Cannabis Increases Risk of Depression in the Case of Genetic Vulnerability, 

2013 - Study ~ Effect of dietary fat type on anxiety-like and depression-like behavior in mice

2013 - Study ~ Translational evidence for the involvement of the endocannabinoid system in stress-related psychiatric illnesses

2013 - Study ~ Screening genetic variability at the CNR1 gene in both major depression etiology and clinical response to citalopram treatment.

2013 - Study ~ Additive effect of rimonabant and citalopram on extracellular serotonin levels monitored with in vivo microdialysis in rat brain.

2013 - Study ~ Entopeduncular nucleus endocannabinoid system modulates sleep-waking cycle and mood in rats.

2013 - Study ~ Can Marijuana Reduce Social Pain?

2013 - Study ~ Sleep Quality Moderates the Relation between Depression Symptoms and Problematic Cannabis Use among Medical Cannabis Users

2013 - Study ~ The effects of anandamide signaling enhanced by the FAAH inhibitor URB597 on coping styles in rats.

2013 - Study ~ Cannabinoids, Neurogenesis and Antidepressant Drugs: Is there a Link?

2013 - Study ~ The endocannabinoid system and emotional processing: A pharmacological fMRI study with ∆9-tetrahydrocannabino

2013 - Study ~ Cannabinoid Receptor Activation Prevents the Effects of Chronic Mild Stress on
Emotional Learning and LTP in a Rat Model of Depression.

2013 - Study ~ Endocannabinoid Signaling in the Etiology and Treatment of Major Depressive Illness.

2013 - Study ~ The endocannabinoid system and its possible role in neurobiology of psychiatric
disorders

2013 - Study ~ Low frequency stimulation evokes serotonin release in the nucleus accumbens and induces long-term depression via production of endocannabinoid.

2013 - Study ~ Testing bidirectional effects between cannabis use and depressive symptoms: moderation by the serotonin transporter gene

2013 - News ~ THC Increases Brain Activity In Response To Positive Stimuli

2013 - News ~ This bud’s for you: Marijuana identified as a buffer against loneliness, study suggests

2013 - News ~ 5 Health Benefits Of Cannabichromene (CBC)

2014 - Study ~ Monoacylglycerol Lipase Inhibition Blocks Chronic Stress-Induced Depressive-Like Behaviors via Activation of mTOR Signaling

2014 - Study ~ Anti-depressive mechanism of repetitive transcranial magnetic stimulation in rat: The role of the endocannabinoid system.

 

Depression Hardcover Books

Overcoming Depression One Step at a Time: The New Behavioral Activation Approach to Getting Your Life BackAnxiety and Depression For Dummies, Pocket EditionThe Noonday Demon: An Atlas of Depression Undoing Depression: What Therapy Doesn't Teach You and Medication Can't Give YouSelf-Coaching: The Powerful Program to Beat Anxiety and Depression, 2nd Edition, Completely Revised and UpdatedTake Control Of Your Life: Self Help For Depression, Anxiety Disorders, Confidence, Success & More

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